Results 321 to 330 of about 2,104,096 (377)
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Development of Mucoadhesive Patches for Buccal Administration of Carvedilol
Current Drug Delivery, 2007A buccal patch for systemic administration of carvedilol in the oral cavity has been developed using two different mucoadhesive polymers. The formulations were tested for in vitro drug permeation studies, buccal absorption test, in vitro release studies, moisture absorption studies and in vitro bioadhesion studies.
K. Chandrasekhar +3 more
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Oral Biodisposition Study of Ritodrine after Its Buccal Administration in Rats.
Current Drug Delivery, 2017BACKGROUND In the previous study, buccal absorption of ritodrine (RD) hydrochloride was reported in vivo. As a result, buccal dosing of RD solution was found to be useful for the maintenance of effective plasma concentration.
H. Onishi, Kei Yumoto, O. Sakata
semanticscholar +1 more source
Veterinary Anaesthesia and Analgesia, 2016
OBJECTIVE To determine the effects of morphine, methadone, hydromorphone or oxymorphone on the thermal threshold in cats, following buccal and intravenous (IV) administration. STUDY DESIGN Randomized crossover study.
B. Pypendop +2 more
semanticscholar +1 more source
OBJECTIVE To determine the effects of morphine, methadone, hydromorphone or oxymorphone on the thermal threshold in cats, following buccal and intravenous (IV) administration. STUDY DESIGN Randomized crossover study.
B. Pypendop +2 more
semanticscholar +1 more source
Development of an Insulin Nano-delivery System through Buccal Administration
Current Drug Delivery, 2022Aim: The aim of the study was to develop a new nano-delivery system for buccal administration of insulin. Background: Biodegradable polymeric nanoparticles (PNPs) had undergone countless breakthroughs in drug delivery systems. The main objective of PNPs application in delivering and carrying different promising drugs is to make sure that the drugs ...
Ayat Bozeya +2 more
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Journal of Veterinary Pharmacology and Therapeutics, 2014
This study reports the pharmacokinetics of buprenorphine, following i.v. and buccal administration, and the relationship between buprenorphine concentration and its effect on thermal threshold.
A. Hedges +4 more
semanticscholar +1 more source
This study reports the pharmacokinetics of buprenorphine, following i.v. and buccal administration, and the relationship between buprenorphine concentration and its effect on thermal threshold.
A. Hedges +4 more
semanticscholar +1 more source
Systemic uptake of buprenorphine after buccal administration in cats
Veterinary Anaesthesia and Analgesia, 2002Administration of drugs to cats can be challenging and simple but effective techniques would be attractive to the owners. The purpose of this study was to compare the pharmacokinetics of buprenorphine (B) after buccal administration, and compare these to data previously collected from the same colony of cats after IV and IM injection.
Sheilah A. Robertson +3 more
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Journal of Veterinary Pharmacology and Therapeutics, 2014
Buccal administration of buprenorphine is commonly used to treat pain in cats. It has been argued that absorption of buprenorphine through the buccal mucosa is high, in part due to its pKa of 8.24. Morphine, methadone, hydromorphone, and oxymorphone have
B. Pypendop +2 more
semanticscholar +1 more source
Buccal administration of buprenorphine is commonly used to treat pain in cats. It has been argued that absorption of buprenorphine through the buccal mucosa is high, in part due to its pKa of 8.24. Morphine, methadone, hydromorphone, and oxymorphone have
B. Pypendop +2 more
semanticscholar +1 more source
Buccal versus intravaginal misoprostol administration for cervical ripening
American Journal of Obstetrics and Gynecology, 2002The purpose of this study was to compare the efficacy of misoprostol that is administered in the buccal pouch with the intravaginal route of administration.One hundred fifty-seven pregnant women with a singleton live gestation, Bishop score of
Stephen J. Carlan +2 more
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Development of chitosan sponges for buccal administration of insulin
Carbohydrate Polymers, 2007Abstract This paper describes the development of a new highly porous, flexible device for buccal peptide administration by a very simple and mild casting/freeze-drying procedure. It consists of a mucoadhesive chitosan layer containing the peptide drug and an impermeable protective layer made of ethylcellulose.
María J. Alonso +3 more
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Absorption behavior of etilefrine after buccal administration in rats
International Journal of Pharmaceutics, 2018Etilefrine hydrochloride (ET-HCl) is used in the treatment of hypotension. Dosage forms of orally administered tablets and parenteral injections are clinically available, but exhibit unfavorable characteristics, including cardiac toxicity, headaches, and damage at the injection site for the parenteral dosage form, and initially high plasma levels, fast
Osamu Sakata, Hiraku Onishi
openaire +3 more sources