Results 331 to 340 of about 2,104,096 (377)
Some of the next articles are maybe not open access.
Journal of Pharmacy and Science, 2014
Antimicrobial approaches are valuable in controlling the development of buccal diseases, but some antibacterial agents have a short duration of activity. Therefore, the development of prolonged delivery systems would be advantageous.
Carla Souza +4 more
semanticscholar +1 more source
Antimicrobial approaches are valuable in controlling the development of buccal diseases, but some antibacterial agents have a short duration of activity. Therefore, the development of prolonged delivery systems would be advantageous.
Carla Souza +4 more
semanticscholar +1 more source
Bioavailability of morphine after administration of a new bioadhesive buccal tablet
Biopharmaceutics & Drug Disposition, 1998A new bioadhesive buccal morphine tablet was developed for controlled release delivery of drug and improved bioavailability compared with oral controlled release tablet. In order to characterize the pharmacokinetic properties of this bioadhesive buccal formulation, a bioavailability study was performed in 12 healthy volunteers who received: a 30 mg ...
J.-M. Aiache +5 more
openaire +3 more sources
Comparison of misoprostol plasma concentrations following buccal and sublingual administration
Contraception, 2005New indications for misoprostol include medical abortion, cervical softening, induction of labor and treatment of postpartum hemorrhage. Various routes of misoprostol administration under study include oral, vaginal, buccal, sublingual and rectal.This was an open-label, randomized, cross-over study of the pharmacokinetic differences of buccal vs ...
Eric A. Schaff +2 more
openaire +3 more sources
Comparison of Oxycodone Pharmacokinetics after Buccal and Sublingual Administration in Children
Clinical Pharmacokinetics, 2006We evaluated and compared the pharmacokinetics of two oral administration routes of oxycodone parenteral liquid (10 mg/mL)--single buccal and sublingual administration--in 30 generally healthy awake children, aged 6-91 months.Two groups of children undergoing inpatient surgery were enrolled.
Merja Lasalmi +6 more
openaire +3 more sources
Sublingual and buccal drug administration in medical emergencies
Medicina Clínica (English Edition)Drug administration is crucial to achieve effective therapeutic drug outcomes. In medical emergencies, it is particularly convenient to use drugs that could be administered as an alternative to traditional routes (as oral or intravenous routes), that are not always suitable in these situations. Thus, sublingual and buccal routes offer an alternative to
Joan Ramon, Roma +2 more
openaire +2 more sources
Mucoadhesive gels for buccal administration of chloexidine digluconate
2005Chlorhexidine (CHX) is a bis-bis-guanide widely used to treat skin and mucosa infections, efficient against a wide range of microbial species. The aim of this work was to design and evaluate gels containing CHX associated to mucoadhesive and swelling agents, such as CMC, HPMC, HPC and Poloxamer, to control both the residence time in the oral cavity and
G. C. Ceschel +5 more
openaire +4 more sources
Journal of Veterinary Pharmacology and Therapeutics, 2019
This study aimed to define the pharmacokinetic profiles of dexmedetomidine and methadone administered simultaneously in dogs by either an oral transmucosal route or intramuscular route and to determine the bioavailability of the oral transmucosal ...
Federica Di Cesare +7 more
semanticscholar +1 more source
This study aimed to define the pharmacokinetic profiles of dexmedetomidine and methadone administered simultaneously in dogs by either an oral transmucosal route or intramuscular route and to determine the bioavailability of the oral transmucosal ...
Federica Di Cesare +7 more
semanticscholar +1 more source
Clinical Pharmacokinetics, 2004
To evaluate the pharmacokinetics of four administration routes of oxycodone parenteral liquid (10 mg/mL), single intravenous and intramuscular injections and buccal and gastric administration, in children.Forty generally healthy children, aged 6-93 months, undergoing inpatient surgery.After induction of anaesthesia, children received a single dose of ...
Kari Vanamo +5 more
openaire +3 more sources
To evaluate the pharmacokinetics of four administration routes of oxycodone parenteral liquid (10 mg/mL), single intravenous and intramuscular injections and buccal and gastric administration, in children.Forty generally healthy children, aged 6-93 months, undergoing inpatient surgery.After induction of anaesthesia, children received a single dose of ...
Kari Vanamo +5 more
openaire +3 more sources
Effectiveness of the Buccal Mucosa Route for Methadone Administration at the End of Life
Journal of Palliative Medicine, 2014Methadone is a useful analgesic for neuropathic and nociceptive pain. However, there is little information about the use of methadone in the final days of life when a patient cannot swallow, discouraging its use by many palliative care physicians.The purpose of this study was to investigate the effectiveness of switching patients on oral methadone at ...
openaire +3 more sources
Pethidine is Unsuitable for Buccal Administration
Pharmacology & Toxicology, 1990Christrup, Lona Louring +4 more
openaire +4 more sources