Results 31 to 40 of about 53,364 (321)

The administration of multipotent stromal cells at precancerous stage precludes tumor growth and epithelial dedifferentiation of oral squamous cell carcinoma [PDF]

open access: yes, 2017
Multipotent stromal cells (MSCs) are envisioned as a powerful therapeutic tool. As they home into tumors, secrete trophic and vasculogenic factors, and suppress immune response their role in carcinogenesis is a matter of controversy.
Arango Rodríguez, Martha   +4 more
core   +1 more source

Factors affecting the buccal delivery of deformable nanovesicles based on insulin–phospholipid complex: an in vivo investigation

open access: yesDrug Delivery, 2020
Deformable nanovesicles (DNVs) have been used in the buccal delivery of biomacromolecules due to their ability to enhance drug penetration. However, no breakthroughs have been made until now due to limited understanding of the factors affecting in vivo ...
Yuqi Yang   +6 more
doaj   +1 more source

Immunopathogenesis of canine chronic ulcerative stomatitis. [PDF]

open access: yes, 2020
Canine Chronic Ulcerative Stomatitis is a spontaneously occurring inflammatory disease of the oral mucosa. An immune-mediated pathogenesis is suspected though not yet proven.
Anderson, JG   +8 more
core   +1 more source

Inhaled Insulin: Intrapulmonary or Intranasal? [PDF]

open access: yes, 2012
Initial attempts delivered the insulin hormone intramuscularly, intravenously, and eventually subcutaneously. Other routes of administration of the drug were explored.
Danish Ahmed   +3 more
core   +2 more sources

The Potential of Films as Transmucosal Drug Delivery Systems

open access: yesPharmaceutics, 2023
Pharmaceutical films are polymeric formulations used as a delivery platform for administration of small and macromolecular drugs for local or systemic action.
Ana Clara Wada de Carvalho   +6 more
doaj   +1 more source

Development of Mucoadhesive Buccal Film for Rizatriptan: In Vitro and In Vivo Evaluation

open access: yesPharmaceutics, 2021
The reduced therapeutic efficacy of rizatriptan in migraine treatment is primarily due to low oral bioavailability and extensive first pass metabolism. The purpose of this investigation was to optimize the thin mucoadhesive buccal film of rizatriptan and
Anroop B. Nair   +6 more
doaj   +1 more source

Microemulsion containing triamcinolone acetonide for buccal administration

open access: yesEuropean Journal of Pharmaceutical Sciences, 2018
The aim of the present work was to investigate the potential of microemulsions for the buccal administration of triamcinolone acetonide. Microemulsions were developed by the construction of pseudoternary phase diagrams, using the aqueous titration method.
C. Padula   +5 more
openaire   +3 more sources

Study of influence of base-vehicle on biological activity of vasopressin in the transbuccal dosage forms

open access: yesAktualʹnì Pitannâ Farmacevtičnoï ì Medičnoï Nauki ta Praktiki, 2019
Understanding of nootropics' lack of strong selectivity is a feature of their study at the modern stage. Speaking about peptides such as vasopressin, influence on the related behavioral forms including linked with a mental and emotional area is also ...
Al Nasir Eiad   +3 more
doaj   +1 more source

Development and evaluation of bioadhesive buccal films based on sodium alginate for allergy therapy

open access: yesHeliyon, 2022
Buccal drug administration is a less explored area, therefore researchers and companies focus on its research because of its innovative potential and opportunities.
Krisztián Pamlényi   +3 more
doaj   +1 more source

Silodosin oral films: Development, physico-mechanical properties and in vitro dissolution studies in simulated saliva [PDF]

open access: yes, 2019
Sublingual film dosage forms for drugs used for fast symptomatic treatment have promise because they allow a rapid onset of action. The aim of this study was to prepare films of silodosin intended for sublingual administration for the symptomatic ...
Adair   +57 more
core   +2 more sources

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