Results 41 to 50 of about 2,104,096 (377)
Treatment of Porphyromonas gulae infection and downstream pathology in the aged dog by lysine-gingipain inhibitor COR388. [PDF]
, 2020 COR388, a small-molecule lysine-gingipain inhibitor, is currently being investigated in a Phase 2/3 clinical trial for Alzheimer's disease (AD) with exploratory endpoints in periodontal disease.
Arastu-Kapur, Shirin +10 more
core +1 more source
Evidence of emerging BBB changes in mid‐age apolipoprotein E epsilon‐4 carriers
Brain and Behavior, Volume 12, Issue 12, December 2022., 2022 This study demonstrated a tendency towards BBB permeability in APOEε4 participants emerging from mid‐age, with quantitative differences observable on a number of the measures. Results from this study may help identify at‐risk populations at an early stage which will be crucial in facilitating the development of early interventions to change the ...
Nourah M. Alruwais +3 more
wiley +1 more source
The Potential of Films as Transmucosal Drug Delivery Systems
Pharmaceutics, 2023 Pharmaceutical films are polymeric formulations used as a delivery platform for administration of small and macromolecular drugs for local or systemic action.
Ana Clara Wada de Carvalho +6 more
doaj +1 more source
Application of biologics for ridge preservation/reconstruction after implant removal
Clinical Advances in Periodontics, Volume 12, Issue 4, Page 270-276, December 2022., 2022 Abstract Background The purpose of this review was aimed at providing the rationale supported with a series of cases to apply biologics to enhance orchestrating the healing process at implant removal sites. Summary Implant removal is commonly applied on a daily basis, in particular, in cases that exhibit esthetic failures linked to inadequate implant ...
Alberto Monje +1 more
wiley +1 more source
Drug Delivery, 2020 Deformable nanovesicles (DNVs) have been used in the buccal delivery of biomacromolecules due to their ability to enhance drug penetration. However, no breakthroughs have been made until now due to limited understanding of the factors affecting in vivo ...
Yuqi Yang +6 more
doaj +1 more source
Development of Mucoadhesive Buccal Film for Rizatriptan: In Vitro and In Vivo Evaluation
Pharmaceutics, 2021 The reduced therapeutic efficacy of rizatriptan in migraine treatment is primarily due to low oral bioavailability and extensive first pass metabolism. The purpose of this investigation was to optimize the thin mucoadhesive buccal film of rizatriptan and
Anroop B. Nair +6 more
doaj +1 more source
Use of the Buccal Route for the Administration of an Antiemetic
Anesthesia & Analgesia, 1992 K. W. Patterson, Padraic W. Keane
openalex +3 more sources
High-fidelity intensity diffraction tomography with a non-paraxial multiple-scattering model [PDF]
Opt. Express 30, 32808-32821 (2022), 2022 We propose a novel intensity diffraction tomography (IDT) reconstruction algorithm based on the split-step non-paraxial (SSNP) model for recovering the 3D refractive index (RI) distribution of multiple-scattering biological samples. High-quality IDT reconstruction requires high-angle illumination to encode both low- and high- spatial frequency ...
arxiv +1 more source
Survey of Provider Preferences Regarding the Route of Misoprostol for Induction of Labor at Term
American Journal of Perinatology Reports, 2017 Objective To survey obstetrical provider preferences regarding use of misoprostol for induction of labor (IOL). Methods An anonymous 25-question survey was distributed at an American College of Obstetricians and Gynecologists (ACOG) joint ...
Rachel Towns +3 more
doaj +1 more source
Advances in oral transmucosal drug delivery [PDF]
, 2011 Original article can be found at : http://sciencedirect.com/ Copyright ElsevierThe successful delivery of drugs across the oral mucosa represents a continuing challenge, as well as a great opportunity.
Brown, Marc +2 more
core +1 more source