Results 111 to 120 of about 2,266,067 (293)
Development and Characterization of Mucoadhesive Film of Nitrendipine for Buccal Administration
Mucoadhesive buccal patches containing nitrendipine were prepared using the solvent casting method. Chitosan was used as bio-adhesive polymer and different ratios of chitosan to PVP K-30 were used. The pre-formulation study using DSC revealed the compatibility of drug and polymer.
Chauhan N, Mittal A , U.K.Bajaj
openaire +2 more sources
Abstract With the development of dental microwear texture analysis (DMTA), there has been an increasing application of DMTA for dietary estimation in extant and fossil reptiles, including dinosaurs. While numerous feeding experiments exist for herbivorous mammals, knowledge remains limited for carnivorous reptiles. This study aimed to qualitatively and
K. Usami, M. O. Kubo
wiley +1 more source
High-speed in vitro intensity diffraction tomography [PDF]
We demonstrate a label-free, scan-free {\it intensity} diffraction tomography technique utilizing annular illumination (aIDT) to rapidly characterize large-volume 3D refractive index distributions in vitro. By optimally matching the illumination geometry to the microscope pupil, our technique reduces the data requirement by 60$\times$ to achieve high ...
arxiv +1 more source
Optimasi Konsentrasi Hidroksipropil Selulosa dan Polivinilpirolidon dalam Sediaan Buccal Film Simvastatin (Optimization Of Hydroxypropyl Cellulose and Polyvynylpyrolidone Concentration in Simvastatin Buccal Film) [PDF]
Simvastatin, an antihyperlipidemia drug belongs to HMG-CoA reductase inhibitor, has extend first-pass metabolism and low bioavailability (5%) with 95-98% protein bond and short half-life (2 hours).
Ameliana, Lidya+2 more
core +2 more sources
Buccal films: Design and in vitro characterization
The oral cavity is an attractive site for the delivery of drugs owing to the ease with which it can be administered. It is now possible to administer drug through mucosal (local effect) and transmucosal (systemic effect) route. In the first case, the aim is to achieve a site-specific release of the drug on the mucosa, whereas the second case involves ...
Udichi Kataria, Chandraprakash Jain
openaire +2 more sources
“FORMULATION AND EVALUATION OF BUCCAL FILMS OF SAXAGLIPTIN”
Objective: Saxagliptin is an orally anti-diabetic drug. It has an oral bioavailability of 50% due to first pass hepatic metabolism. To achieve sustained action of drug, reduce dosing frequency, bypass the hepatic first pass effect and improve bioavailability, buccal films formulation was planned. Methods: Compatibility of the drug with the ...
Vipul Pandit, Vijay Patel
openaire +3 more sources
ABSTRACT Background Adenoid cystic carcinoma (ACC) is the second most common and treatment‐resistant salivary gland carcinoma (SGC). Although platinum‐based therapies are effective, the efficacy of eribulin, a microtubule inhibitor with an 18% response rate in a Phase II trial involving recurrent/metastatic SGC, in patients with advanced ACC after ...
Tomomi Sanomachi+16 more
wiley +1 more source
The prevalence of impacted permanent maxillary canines in Maltese school children : a pilot study [PDF]
The aetiology of ectopic canines is not clear. A number of causes have been put forward such as the long path of eruption of the maxillary canine, lack of guidance by the lateral incisor root, narrow arches, cystic enlargement of the dental follicle ...
Camilleri, Simon
core
Formulation and Optimization of Oral Mucoadhesive Patches of Myrtus Communis by Box Behnken Design [PDF]
Purpose: Recurrent aphthous stomatitis (RAS) is the most common painful ulcerative disease of oral mucosa happening in ~20% of people. Aimed to develop Myrtus communis L.
Fanaei, Hamed+6 more
core +3 more sources
Objective: Saliva maintains vital mouth functions and acts as a barrier to dental health. Xerostomia, which is characterised as a feeling of dry mouth, adversely affects the patient’s quality of life.
Özlem Akbal Dağıstan+3 more
doaj +1 more source