Results 111 to 120 of about 2,266,067 (293)

Development and Characterization of Mucoadhesive Film of Nitrendipine for Buccal Administration

open access: yesInternational Journal of Nano Studies & Technology, 2013
Mucoadhesive buccal patches containing nitrendipine were prepared using the solvent casting method. Chitosan was used as bio-adhesive polymer and different ratios of chitosan to PVP K-30 were used. The pre-formulation study using DSC revealed the compatibility of drug and polymer.
Chauhan N, Mittal A , U.K.Bajaj
openaire   +2 more sources

In‐vitro puncture experiment using alligator teeth tracks the formation of dental microwear and its association with hardness of the diet

open access: yesThe Anatomical Record, EarlyView.
Abstract With the development of dental microwear texture analysis (DMTA), there has been an increasing application of DMTA for dietary estimation in extant and fossil reptiles, including dinosaurs. While numerous feeding experiments exist for herbivorous mammals, knowledge remains limited for carnivorous reptiles. This study aimed to qualitatively and
K. Usami, M. O. Kubo
wiley   +1 more source

High-speed in vitro intensity diffraction tomography [PDF]

open access: yes, 2019
We demonstrate a label-free, scan-free {\it intensity} diffraction tomography technique utilizing annular illumination (aIDT) to rapidly characterize large-volume 3D refractive index distributions in vitro. By optimally matching the illumination geometry to the microscope pupil, our technique reduces the data requirement by 60$\times$ to achieve high ...
arxiv   +1 more source

Optimasi Konsentrasi Hidroksipropil Selulosa dan Polivinilpirolidon dalam Sediaan Buccal Film Simvastatin (Optimization Of Hydroxypropyl Cellulose and Polyvynylpyrolidone Concentration in Simvastatin Buccal Film) [PDF]

open access: yes, 2017
Simvastatin, an antihyperlipidemia drug belongs to HMG-CoA reductase inhibitor, has extend first-pass metabolism and low bioavailability (5%) with 95-98% protein bond and short half-life (2 hours).
Ameliana, Lidya   +2 more
core   +2 more sources

Buccal films: Design and in vitro characterization

open access: yes, 2015
The oral cavity is an attractive site for the delivery of drugs owing to the ease with which it can be administered. It is now possible to administer drug through mucosal (local effect) and transmucosal (systemic effect) route. In the first case, the aim is to achieve a site-specific release of the drug on the mucosa, whereas the second case involves ...
Udichi Kataria, Chandraprakash Jain
openaire   +2 more sources

“FORMULATION AND EVALUATION OF BUCCAL FILMS OF SAXAGLIPTIN”

open access: yesInternational Journal of Pharmaceutical and Biological Science Archive, 2019
Objective: Saxagliptin is an orally anti-diabetic drug. It has an oral bioavailability of 50% due to first pass hepatic metabolism. To achieve sustained action of drug, reduce dosing frequency, bypass the hepatic first pass effect and improve bioavailability, buccal films formulation was planned. Methods: Compatibility of the drug with the ...
Vipul Pandit, Vijay Patel
openaire   +3 more sources

Efficacy of Eribulin Monotherapy in Patients With Unresectable and/or Metastatic Adenoid Cystic Carcinoma Receiving Platinum‐Based Therapy

open access: yesHead &Neck, EarlyView.
ABSTRACT Background Adenoid cystic carcinoma (ACC) is the second most common and treatment‐resistant salivary gland carcinoma (SGC). Although platinum‐based therapies are effective, the efficacy of eribulin, a microtubule inhibitor with an 18% response rate in a Phase II trial involving recurrent/metastatic SGC, in patients with advanced ACC after ...
Tomomi Sanomachi   +16 more
wiley   +1 more source

The prevalence of impacted permanent maxillary canines in Maltese school children : a pilot study [PDF]

open access: yes, 1995
The aetiology of ectopic canines is not clear. A number of causes have been put forward such as the long path of eruption of the maxillary canine, lack of guidance by the lateral incisor root, narrow arches, cystic enlargement of the dental follicle ...
Camilleri, Simon
core  

Formulation and Optimization of Oral Mucoadhesive Patches of Myrtus Communis by Box Behnken Design [PDF]

open access: yes, 2017
Purpose: Recurrent aphthous stomatitis (RAS) is the most common painful ulcerative disease of oral mucosa happening in ~20% of people. Aimed to develop Myrtus communis L.
Fanaei, Hamed   +6 more
core   +3 more sources

DEVELOPMENT AND EVALUATION OF BIOADHESIVE MUCOSAL DOSAGE FORMS OF PILOCARPINE HCL FOR XEROSTOMIA THERAPY

open access: yesSabiad
Objective: Saliva maintains vital mouth functions and acts as a barrier to dental health. Xerostomia, which is characterised as a feeling of dry mouth, adversely affects the patient’s quality of life.
Özlem Akbal Dağıstan   +3 more
doaj   +1 more source

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