Results 91 to 100 of about 39,495 (291)

Reinforcing Doses of Diphtheria Toxoid Absorbed Through the Buccal Mucosa [PDF]

, 1961
W. C. Cockburn, C. M. Patricia Bradstreet, M E Bailey, J. Ungar   +3 more
openalex   +1 more source

Impact of WPOI‐5 on Risk of Regional Recurrence in Early Oral Cancer With pN0 Neck

The Laryngoscope, EarlyView.
In the present retrospective study, worst pattern of invasion category 5 (WPOI‐5) was found to be significantly associated with regional recurrence (RR) among patients with early oral cancer and pathologically negative necks after elective neck dissection. Isolated RR was seen only among patients not receiving postoperative radiotherapy (PORT), however,
Justin Hintze, Nadia van den Berg, Deirdre Callanan, Shima Mohamed, Linda Feeley, Patrick Sheahan   +5 more
wiley   +1 more source

Malignant Transformation Rate of Oral Premalignant Disorders: A Large Database Analysis

The Laryngoscope, EarlyView.
ABSTRACT Objectives Oral leukoplakia (OL), oral lichen planus (OLP), and oral submucous fibrosis (OSF) are precancerous lesions known to progress to oral squamous cell carcinoma (OSCC). The transformation rates to OSCC are controversial and have been based on small, heterogeneous, single‐institution studies. We present the largest study to date looking
Andrew Meci, Neerav Goyal, David Goldenberg   +2 more
wiley   +1 more source

Recent Advances in Injectable Hydrogel Biotherapeutics for Regenerative Dental Medicine

Macromolecular Bioscience, EarlyView.
This review analyses multifunctional injectable hydrogels, natural or synthetic, physically or chemically crosslinked, that deliver exosomes, stem cells, and other bioactive cues to inflamed or damaged oral tissues. We discuss their immunomodulatory, antimicrobial, angiogenic, and osteogenic capacities, highlighting advances that enable regenerative ...
Renan Dal‐Fabbro, Arwa Daghrery, Caroline Anselmi, Igor Paulino M. Soares, Alexandre Henrique dos Reis‐Prado, Pedro Henrique Chaves de Oliveira, Marco C. Bottino   +6 more
wiley   +1 more source

Innate immune signaling in hearts and buccal mucosa cells of patients with arrhythmogenic cardiomyopathy

Heart Rhythm O2, 2023
Background: Nuclear factor κB (NF-κB) signaling in cardiac myocytes causes disease in a mouse model of arrhythmogenic cardiomyopathy (ACM) by mobilizing CCR2-expressing macrophages that promote myocardial injury and arrhythmias.
Carlos Bueno-Beti, PhD, Alessandro Tafuni, MD, Stephen P. Chelko, PhD, FHRS, Mary N. Sheppard, MD, Ella Field, MSc, Jennifer Tollit, MSc, Imogen K. Heenan, BSc, Annabelle Barnes, BSc, Matthew R. Taylor, MD, PhD, Luisa Mestroni, MD, Juan Pablo Kaski, MD, Jeffrey E. Saffitz, MD, PhD, FHRS, Angeliki Asimaki, PhD   +12 more
doaj  

Predictive Factors of Free Flap Volume Evolution in Head and Neck Reconstruction

Otolaryngology–Head and Neck Surgery, EarlyView.
Abstract Objective The aim of our study was to determine the factors influencing the evolution of the total volume and bone volume of free flaps commonly used in head and neck surgery, with a 30‐month prospective study, to establish volume change predictions and thus propose a degree of overcorrection to be expected before reconstruction.
Quentin Hennocq, Jean‐Baptiste Caruhel, Mourad Benassarou, Jebrane Bouaoud, André Chaine, Angélique Girod, Nicolas Graillon, Sylvie Testelin, Mélika Amor‐Sahli, Jean‐Philippe Foy, Chloé Bertolus   +10 more
wiley   +1 more source

Management and Outcomes of Postoperative Airway Obstruction in Patients After Tissue‐Augmentation Palatoplasty

Otolaryngology–Head and Neck Surgery, EarlyView.
Abstract Objective To characterize postoperative airway obstruction and evaluate management strategies in pediatric patients with cleft palate following tissue‐augmentation palatoplasty (TAP). Study Design Retrospective case series. Setting Single academic center. Methods Patients with obstruction within 1 year of primary TAP between 2017 and 2023 were
Pooja D. Reddy, Soukaina Eljamri, Amber D. Shaffer, Matthew Ford, Rachel Whelan, Allison Tobey, Noel Jabbour   +6 more
wiley   +1 more source

New insights into the genetic progression of cancer through longitudinal analysis of oral lesions

The Journal of Pathology, EarlyView.
Abstract Genetic progression models of cancer continue to determine the roadmap of carcinogenesis, although the sequence of genetic events is inferred rather than empirically determined through longitudinal analyses. Here, we present a unique longitudinal study of oral leukoplakia lesions that transformed into carcinoma.
Leon J Wils, Jos B Poell, Arjen Brink, Laura AN Peferoen, Ilkay Evren, Elisabeth R Brouns, Jan GAM de Visscher, Erik H van der Meij, Elisabeth Bloemena, Ruud H Brakenhoff   +9 more
wiley   +1 more source

Genetic Diagnosis and Clinical Features of Fetuses With Congenital Diaphragmatic Hernia

Prenatal Diagnosis, EarlyView.
ABSTRACT Objective Congenital diaphragmatic hernia (CDH) is a rare abnormality with highly heterogeneous genetic causes. This study investigated chromosomal and monogenic abnormalities in fetal CDH patients and evaluated the efficacy of chromosomal microarray analysis (CMA) and whole‐exome sequencing (WES) for genetic diagnosis.
Yan Lü, Yi Yu, Jiazhen Chang, Mengmeng Li, Xueting Yang, Xiya Zhou, Na Hao, Hua Meng, Zhenghong Li, Lishuang Ma, Hui You, Shan Jian, Ying Wang, Shengjie Li, Yiqing Yu, Kaili Yin, Mingming Wang, Yulin Jiang, Qingwei Qi   +18 more
wiley   +1 more source

Intranasal diamorphine population pharmacokinetics modeling and simulation in pediatric breakthrough pain

CPT: Pharmacometrics &Systems Pharmacology, Volume 14, Issue 3, Page 435-447, March 2025.
Abstract Intranasal diamorphine (IND), approved for managing breakthrough pain in the UK, has been identified as an acceptable alternative offering effective, expedient, and less traumatic analgesia for children. However, the current dose regimen in pediatric populations relies on clinical expertise while the pharmacokinetics properties are poorly ...
Lianjin Cai, Jingchen Zhai, Beihong Ji, Fengyang Han, Taoyu Niu, Luxuan Wang, Junmei Wang   +6 more
wiley   +1 more source