Results 271 to 280 of about 168,700 (356)

Decreased femoral fracture load after cephalomedullary nail removal : a biomechanical ex vivo study. [PDF]

Bone Joint Res
Schwarz GM, Synek A, Huber S, Hofstaetter JG, Pahr D, Reisinger A, Nürnberger S, Hirtler L.   +7 more
europepmc   +1 more source

Enhanced Activities of OCT4 and SOX2 Promote Epigenetic Reprogramming by Shortening G1 Phase

Advanced Science, EarlyView.
Fusing the VP16 domain to OCT4 and SOX2 (OvSvK) enhances iPSC generation by activating downstream targets, including those regulating the cell cycle. This accelerates reprogramming by shortening the G1 phase and reducing H3K27me3 levels. Modulating Ccnd1, Cdkn2a, and Ccne1 improves efficiency, linking cell cycle to epigenetic remodeling.
Lin Guo, Jiechun Lin, Qiwen Ren, Hao Sun, Yanhua Wu, Haofei Ge, Xiaolan Wu, Lihui Lin, Lining Liang, Changpeng Li, He Liu, Yuangbang Mai, Shilong Chu, Jiadong Liu, Jing Liu, Jiekai Chen, Duanqing Pei, Hui Zheng   +17 more
wiley   +1 more source

Internal 40-gauge microneedle drainage for the management of subretinal fluid in rhegmatogenous retinal detachment surgery. [PDF]

Int J Retina Vitreous
Reiter GS, Krivit J, Ye RZ, Iezzi R.
europepmc   +1 more source

Buckling of a Cylindrical Shell Stiffened by Spiral Stiffeners under External Pressure

, 1969
Yoshiyuki YAMAMOTO, Katsuhiko WATANABE, Tokio NAKAMURA   +2 more
openalex   +2 more sources

Aging and the Spectral Properties of Brain Hemodynamics

Advanced Science, EarlyView.
As the brain ages, its metabolic demands decline—but not uniformly. Here, spectral slope flattening of resting‐state fMRI signals is proposed as a potential biomarker of pathologic brain aging. A subset of older adults diverges from youthful spectral and metabolic patterns, with changes linked to frontal white matter pathology and regional loss of ...
Ki Yun Park, Abraham Z. Snyder, Manu S. Goyal, Timothy O. Laumann, John J. Lee, Babatunde Adeyemo, Nicholas Metcalf, Andrei G. Vlassenko, Joshua S. Shimony, Eric C. Leuthardt   +9 more
wiley   +1 more source

Choroidal and Retinal OCTA Parameters after Scleral Buckling. [PDF]

J Ophthalmic Vis Res
Moradian S, Dehghan M, Seifi MB, Dastmardi M, Suri F.   +4 more
europepmc   +1 more source

Attenuated Nuclear Tension Regulates Progerin‐Induced Mechanosensitive Nuclear Wrinkling and Chromatin Remodeling

Advanced Science, EarlyView.
The premature aging‐related progerin leads to defective nuclear morphology and is associated with disrupted molecular coupling between the extranuclear cytoskeleton and lamin‐associated nuclear envelope. It is discovered that progerin expression reduces nuclear tension, forms nuclear wrinkling, and enhances chromatin dynamics, thereby regulating ...
Ji‐Eun Park, Juhyeon Jo, Kun Xu, Sun‐Ah Lee, Seong‐Beom Han, YigJi Lee, Won‐Ki Cho, Bo Li, Soo Hyun Kim, Dong‐Hwee Kim   +9 more
wiley   +1 more source

Investigating orbital foreign device-associated malignancies: a scoping review. [PDF]

BMC Cancer
Ha JH, Arora JS, Sayadi JJ, Khattab NR, Francis SD, Johnstone TM, Jang Y, Lee GK.   +7 more
europepmc   +1 more source

A Myelin Debris Cleaner for Spinal Cord Injury Recovery: Polycaprolactone / Cell Membrane Assembled Scaffolds

Advanced Science, EarlyView.
pMM‐PCL, made up of pretreated macrophage menbrane and polycaprolactone, boasts the adsorption of harmful myelin debris in the microenvironment of spinal cord injury. Abstract After spinal cord injury (SCI), a mass of myelin debris derived from injured myelin sheath will be consistently generated and induce macrophages to be foam cells.
Yuchen Zhou, Tao Xu, Yiyan Zhou, Nuo Chen, Zhengchao Wu, Zongze Yang, Changwei Yang, Xiaoqing Chen   +7 more
wiley   +1 more source

Internal drainage of subretinal fluid during scleral buckling with 27-Gauge wide angle viewing system and flute needle for rhegmatogenous retinal detachment. [PDF]

Int Ophthalmol
Xie L, Qiao G, Zhang X, Tang Z, Zou Q, He C, Cao K, Dong W, Liao W, Chen D.   +9 more
europepmc   +1 more source