Results 31 to 40 of about 2,479 (287)
Hydrostatic pressure activates HIF‐1α via β‐catenin to promote stemness in breast cancer cells
FEBS Open Bio, EarlyView.To mimic the elevated intestinal fluid pressure in breast cancers, we loaded human breast cancer cells (MCF‐7, MDA‐MB‐453, and BT‐474) to 50 mmHg hydrostatic pressure. Hydrostatic pressure exposure upregulated HIF‐1α and induced stemness in MCF‐7 and BT‐474 cells.
Da Zhai +8 more
wiley +1 more source
The date of the bucolic poet Martius Valerius [PDF]
, 2017 The collection of four Latin bucolics ascribed to one Martius Valerius was only published in the twentieth century; they have been widely considered as twelfth-century compositions.
Justin A. Stover, Stover, Justin
core +1 more source
Ionomycin suppresses cancer cell growth by disrupting mitochondrial transcription
FEBS Open Bio, EarlyView.In this study, we identify a new function for the selective Ca2+ ionophore, ionomycin, as an inhibitor of mitochondrial transcription. Both total and nascent RNA analyses revealed that ionomycin treatment reduces the transcription of mitochondrial genes.
Lishen Wang +10 more
wiley +1 more source
FEBS Open Bio, EarlyView.TGF‐β1 stimulation downregulates lysosomal channel TRPML1 in pulmonary fibroblasts. The TRPML1 agonist ML‐SA5 suppressed fibroblast‐to‐myofibroblast activation and collagen production. Mechanistically, ML‐SA5 inhibited mTOR phosphorylation, restored autophagic flux, and its effects were enhanced by rapamycin (mTOR inhibitor) and reversed by MHY1485 ...
Jiatong Yao +10 more
wiley +1 more source
Lycoris Galli/Volumnia Cytheris: a Greek Courtesan in Rome
Eugesta, 2011 This article analyzes the strategic representation of an elegiac mistress (puella), Gallus’ Lycoris, and her putative inspiration, the freedwoman and mime‑actress Volumnia Cytheris, across a number of Latin literary genres, both verse (elegy ...
Alison Keith
doaj +1 more source
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective Stereoelectroencephalography‐guided radiofrequency thermocoagulation (SEEG‐RFTC) has emerged as a safe and effective minimally invasive treatment for children with drug‐resistant focal epilepsy. Although evidence from real‐world studies remains limited, numerous pediatric cases have demonstrated promising outcomes. This retrospective
Weitao Chen +7 more
wiley +1 more source
Colluthus' Pastoral Traditions: Narrative Strategies and Bucolic Criticism in the Abduction of Helen
, 2008 It is nowadays a commonplace to state that every literary genre is a highly selective segment of a broader world of potential representations, and presents itself to the reader as a complete, self-contained model of interpretable mimesis of that ...
Lucia Prauscello
core +1 more source
La "sampogna" e la "musette". Sannazaro e Jean Lemaire [PDF]
Parole Rubate, 2016 Printed in Paris in early 1504, Le Temple d’Honneur et de Vertus by Jean Lemaire de Belges is one of the most representative examples of the bucolic genre in Renaissance France. Besides its ancient and modern sources, its textual filigree reveals a close
Carlo Vecce
doaj
Cykl poetycki do Hyelli ze zbioru Lusus Andrei Navagera – wstęp, przekład, komentarz
Terminus, 2023 A poetic cycle on Hyella from Andrea Navagero’s Lusus: introduction, translation, commentary The paper presents the first Polish translation of a mini-series of six short poems about Hyella by ...
Elżbieta Górka
doaj +1 more source
Choroid Plexus Enlargement and USPIO‐Based Inflammatory Feature in Cerebral Small Vessel Disease
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective The choroid plexus (CP) is a key component of the blood–cerebrospinal fluid barrier (BCSFB), but its mechanism of action in cerebral small vessel disease (CSVD) remains unclear. This study investigated CP volume (CPV) alterations and their association with conventional imaging markers in CSVD and explored the underlying role of ...
Yongqiang Qu +11 more
wiley +1 more source