Results 151 to 160 of about 71,959 (226)

Distinct Proteomic and Glycosylation Signatures Differentiate A549 Tumor and BEAS-2B Nontumor Cell Line-Derived Small Extracellular Vesicles. [PDF]

Mol Cell Proteomics
Balbisi M, Langó T, Horváth VN, Pál D, Schlosser G, Kecskeméti G, Szabó Z, Ilyés K, Nagy N, Tóth O, Zheng J, Lageveen-Kammeijer GSM, Visnovitz T, Varga Z, G Vértessy B, Turiák L.   +15 more
europepmc   +1 more source

Novel approaches for drug development against chronic primary pain: A systematic review

British Journal of Pharmacology, EarlyView.
Abstract Chronic primary pain (CPP) persisting for more than 3 months, associated with significant emotional distress without any known underlying cause, is an unmet medical need. Traditional or adjuvant analgesics do not provide satisfactory pain relief for a great proportion of these patients.
Valéria Tékus, Éva Borbély, Andreas Goebel, Ralf Baron, Zsófia Hajna, Zsuzsanna Helyes   +5 more
wiley   +1 more source

Anti-Inflammatory Effects of Flavonoids in an LPS-Induced In Vitro Model of Canine Chronic Enteropathy. [PDF]

Animals (Basel)
Móritz AV, Horváth NL, Márton RA, Szilasi A, Jerzsele Á, Psáder R, Farkas O.   +6 more
europepmc   +1 more source

Novel drugs approved by the EMA, the FDA and the MHRA in 2025: A year in review

British Journal of Pharmacology, EarlyView.
Abstract In the 2025 novel drug mini‐review, one can take a full measure of the ingenuity that underlies current drug design and development, despite the year's smaller harvest (46 novel drugs) compared to 2024 (53) and 2023 (70). 54% of the novel drugs are first‐in‐class (FIC).
Andreas Papapetropoulos, Stavros Topouzis, Steve P. H. Alexander, Miriam M. Cortese‐Krott, Zsuzsanna Helyes, Kirill Martemyanov, Claudio Mauro, Nithyanandan Nagercoil, Reynold A. Panettieri Jr, Hemal H. Patel, Rainer Schulz, Barbara Stefanska, Gary J. Stephens, Nathalie Vergnolle, Xin Wang, Stephen Ward, Péter Ferdinandy   +16 more
wiley   +1 more source

Reimagining o-Carborane-Based Fluorophores: Charge-Transfer from Boron Substituents Triggers Aggregation- and Crystallization-Induced Emission. [PDF]

Angew Chem Int Ed Engl
Szathmári B, Gao Y, Buzsáki D, Zámbó D, Holczbauer T, Udvardy A, Szabó P, Kertész J, Hessz D, Kelemen Z.   +9 more
europepmc   +1 more source

TNMplot: An enhanced platform for pharmacological target identification through cross‐stage and pan‐cancer gene expression analysis

British Journal of Pharmacology, EarlyView.
TNMplot.com, a web‐based platform integrating RNA‐Seq and gene‐chip data from 56,938 samples, enables differential gene expression analysis across normal, primary tumour and metastatic tissues, facilitating large‐scale transcriptomic profiling across 22 tumour types.
Áron Bartha, Balázs Győrffy
wiley   +1 more source

Genomic characterization of non-O1, non-O139 Vibrio cholerae causing rare clinical manifestation. [PDF]

BMC Infect Dis
Henczkó J, Vargha M, Kállai A, Kristóf K, Tóth Á, Tóth S, Pályi B, Khayer B, Róka E, Novák B, Mag T, Mezei E, Molnár Z, Kis Z.   +13 more
europepmc   +1 more source

Algorithms in Allergy: Hereditary Angioedema

Allergy, EarlyView.
Konrad Bork, Markus Magerl, Emel Aygören‐Pürsün, Henriette Farkas   +3 more
wiley   +1 more source

NetMetaEasy: enabling rapid and user‐friendly network meta‐analysis (NMA) for comparative effectiveness research

British Journal of Pharmacology, EarlyView.
Background and Purpose Network meta‐analysis (NMA) enables the simultaneous comparison of multiple treatments by combining direct and indirect evidence across a network of studies. While its application is rapidly expanding in pharmacological research and clinical guideline development, performing NMA typically requires advanced statistical knowledge ...
János Tibor Fekete, András Komócsi, Balázs Győrffy   +2 more
wiley   +1 more source

Differences in Continuous Glucose Monitoring Metrics Between Prediabetes and Normoglycemia: A Systematic Review and Meta-Analysis. [PDF]

J Diabetes Sci Technol
Rákóczi G, Nagy J, Jozaee S, Jozaee S, Szentes BL, Lee J, Rancz A, Hegyi P, Agócs G, Sipter E.   +9 more
europepmc   +1 more source