Results 171 to 180 of about 75,284 (250)

Upregulated GLUT1 expression correlates with type I interferon activity and disease severity in cutaneous lupus erythematosus. [PDF]

J Transl Autoimmun
Bokor LA, Szabolcs BL, Király Z, Mohos A, Szepesi Á, Varga V, Sebestyén A, Kemény LV, Holló P, Hidvégi B.   +9 more
europepmc   +1 more source

Comparison of computed tomographic, radiographic and anatomical dorsal hoof wall measurements

Equine Veterinary Education, EarlyView.
Summary Background No comparison of radiographic and computed tomographic (CT) dorsal hoof wall (DHW) thickness and DHW to the palmar length of the distal phalanx (DHWDP) ratio has been published. Radiographic measurements obtained with and without radiodense markers on the DHW have not been compared.
S.‐M. Obitayo, D. Pollard, L. Szabó, A. Nagy   +3 more
wiley   +1 more source

Clinical practice patterns in the pre-endoscopic management of individuals presenting with acute upper gastrointestinal bleeding: results of an international survey. [PDF]

Ther Adv Gastroenterol
Obeidat M, Floria DE, Teutsch B, Abonyi-Tóth Z, Laursen SB, Camus M, Verdonk F, Vincze Á, Bognár Z, Drug V, Siau K, Gralnek IM, Hegyi P, Erőss B.   +13 more
europepmc   +1 more source

Quantitative analysis of DNA‐GATA1 binding alterations linked to hematopoietic disorders

The FEBS Journal, EarlyView.
Native holdup allows the quantitative determination of affinities between full‐length transcription factors and DNA. Mutations in either the protein or the DNA can modulate binding strength, which can be precisely quantified using this approach. Applied to GATA1, it revealed mutations that alter DNA binding.
Boglarka Zambo, Bastien Morlet, Luc Negroni, Orsolya Mózner, Balázs Sarkadi, Gilles Travé, Gergo Gogl   +6 more
wiley   +1 more source

The sorting nexin Snx21 promotes flotillin‐mediated endocytosis

The FEBS Journal, EarlyView.
In this study, we describe a novel function of the previously uncharacterized Snx21 protein as a specific positive regulator of flotillin‐mediated endocytic trafficking. Snx21 is recruited to endosomal membranes via binding to PI(3)P, and it colocalizes with flotillins on the surface of late endosomes.
Tamás Maruzs, Enikő Lakatos, Dalma Feil‐Börcsök, Gábor Juhász, Regina Mező, Asha Kiran Maddali, András Blastyák, Aladár Pettkó‐Szandtner, Hajnalka Laczkó‐Dobos, Gábor Juhász   +9 more
wiley   +1 more source

Mapping Functionally Relevant Tractable Lysines of Challenging Protein Targets by Covalent Fragment Screening. [PDF]

Chembiochem
Csorba N, Ábrányi-Balogh P, Orgován Z, Szalai TV, Ferenczy GG, Kollár L, Péczka N, Imre T, Simon J, Szabó P, Schlosser G, Hrast M, Gobec S, Ivanova V, Galdeano C, Kopranovic A, Neumann M, Meyer-Almes FJ, Keserű GM.   +18 more
europepmc   +1 more source

TOP1MT rs2293925 is an enhancer‐active regulatory SNP that shapes mitochondrial R‐loop dynamics

The FEBS Journal, EarlyView.
This study shows how a common genetic variant of mitochondrial topoisomerase 1 (TOP1MT rs2293925) can influence mitochondrial gene regulation, DNA topology, and formation of noncanonical nucleic acid structures such as R‐loops. By linking this enhancer‐active variant to mitochondrial nucleic acid stress in cellular contexts relevant to amyotrophic ...
Dóra Varga, Zsolt Ráduly, Beáta Boros‐Oláh, Éva Nagy, Zsolt Karányi, László Halász, Bálint László Bálint, György Vámosi, Emese Tóth, Péter Bai, Serena Santangelo, Patrizia Bossolasco, Antonia Ratti, Vincent Géli, Yves Pommier, Lóránt Székvölgyi   +15 more
wiley   +1 more source