Results 211 to 220 of about 248,720 (268)

TOP1MT rs2293925 is an enhancer‐active regulatory SNP that shapes mitochondrial R‐loop dynamics

open access: yesThe FEBS Journal, EarlyView.
This study shows how a common genetic variant of mitochondrial topoisomerase 1 (TOP1MT rs2293925) can influence mitochondrial gene regulation, DNA topology, and formation of noncanonical nucleic acid structures such as R‐loops. By linking this enhancer‐active variant to mitochondrial nucleic acid stress in cellular contexts relevant to amyotrophic ...
Dóra Varga   +15 more
wiley   +1 more source

CD36‐mediated lipid rewiring in the metabolic adaptation of tumour ecosystems

open access: yesThe FEBS Journal, EarlyView.
Nutrient deprivation drives a lipid‐centric shift in tumour metabolic symbiosis and signalling network. CD36 functions as a bidirectional bridge, transferring fatty acids from stromal donors (adipocytes, CAFs) to the ecosystem tumour‐ and microenvironment‐dependently.
Anna Sebestyén   +11 more
wiley   +1 more source

Diagnostic accuracy of noninvasive optical imaging for basal cell carcinoma: A systematic review and meta-analysis. [PDF]

open access: yesJAAD Int
Kelemen BA   +10 more
europepmc   +1 more source

Stroma AReactive Invasion Front Areas (SARIFA) is a negative prognostic factor for overall survival in non‐intestinal gastric adenocarcinomas

open access: yesHistopathology, EarlyView.
SARIFA – characterized by direct tumour cell‐adipocyte contact – is a novel histological marker that is easily identifiable on standard haematoxylin–eosin‐stained sections and is associated with aggressive tumour behaviour. SARIFA positivity independently predicts poorer survival outcomes in non‐intestinal gastric cancer and may thus contribute to ...
Ákos Jakab   +10 more
wiley   +1 more source

Towards a unified publicly accessible database of avian type specimens

open access: yesIbis, EarlyView.
Type specimens represent the crucial physical reference for any scientific bird name, but type material is scattered widely across the globe, and there is still no one comprehensive source documenting the presence, status and condition of all avian type specimens, as well as associated information on nomenclature and the validity of individual names ...
Guy M. Kirwan   +6 more
wiley   +1 more source

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