Results 251 to 260 of about 67,636 (336)

Do drugs approved via expedited approval pathways have therapeutic advantages? A systematic review and meta‐analysis

British Journal of Clinical Pharmacology, EarlyView.
Regulators use expedited approval pathways to speed market approval and patient access to promising new drugs. However, there is uncertainty about whether these pathways are successful in approving drugs with significant therapeutic advantages. This systematic review aims to examine the safety, effectiveness and cost‐effectiveness of drugs approved via
Ashleigh Hooimeyer, Eliza J. McEwin, Zhicheng Wang, Joel Lexchin, Barbara Mintzes   +4 more
wiley   +1 more source

The Physics, Information, and Computation of Perennial Learning: Kolmogorov Complexity, Information Distance, and Port-Hamiltonian Thermodynamics. [PDF]

Entropy (Basel)
Bajaj C.
europepmc   +1 more source

Precision medicine in paediatrics: Progress and priorities

British Journal of Clinical Pharmacology, EarlyView.
Precision medicine is revolutionizing personalized healthcare, advancing both diagnostics and therapeutics at an unprecedented pace. Reviewing the paediatric applications of pharmacometrics, pharmacogenomics and advanced therapy medicinal products highlights not only the relevance of these exciting innovations to frontline care but also the significant
Nicola Husain, Claire Booth, Joseph F. Standing, Charlotte I. S. Barker   +3 more
wiley   +1 more source

Stabilizing updates in differentially private stochastic gradient descent with buffered rejection. [PDF]

Sci Rep
Deng S, Zhang K, Zhang W, Jiang H, Tsai PW.   +4 more
europepmc   +1 more source

Young children's right to be heard on the quality of their education: Addressing potential misunderstandings in the context of early childhood education

British Educational Research Journal, EarlyView.
Abstract In early childhood education many researchers and professionals across the world have embraced the United Nations Convention on the Rights of the Child's requirement to include young children in decision‐making. In the context of ongoing discussion about young children's capacity to share their views and opinions about matters affecting them ...
Laura Lundy, Colette Murray, Kylie Smith, Carmel Ward   +3 more
wiley   +1 more source

Bi-objective location-allocation model of interventions in high drug consumption areas incorporating X topic modeling. [PDF]

Health Care Manag Sci
Palomino K, Berdugo C, Acuña J, Zayas-Castro JL.   +3 more
europepmc   +1 more source

Balancing Reproduction and Survival: Seasonal Body Mass Dynamics in a High-Altitude Primate (<i>Rhinopithecus bieti</i>). [PDF]

Animals (Basel)
Li YP, Huang ZP, Grueter CC, He XB, Pan RL, He XM, Yang GW, Wu H, Cui LW, Xiao W.   +9 more
europepmc   +1 more source

Fitness Distance Balanced Starfish Optimization for Benchmark and Engineering Design Problems. [PDF]

Biomimetics (Basel)
Yağbasan T, Akyazı Ö, Türe H, Dizdaroğlu B.   +3 more
europepmc   +1 more source

Optimizing Budget Allocation for Digital Health Investments Using Metaheuristic Algorithms: A Cost-Impact Analysis for Public Health Systems. [PDF]

Healthcare (Basel)
Dayi F, Erdogdu A, Esmer Y, Yildiz F, Ganji F.   +4 more
europepmc   +1 more source