Results 1 to 10 of about 8,448,017 (179)
Affordability of oncology drugs: accuracy of budget impact estimations
Background: In many countries, Budget Impact (BI) informs reimbursement decisions. Evidence has shown that decision-makers have restricted access based on high BI estimates but studies show that BI estimates are often inaccurate. Objective: To assess the
Joost W. Geenen +4 more
doaj +2 more sources
Cost-effectiveness and budget impact of Luspatercept in Thai adults with transfusion-dependent beta-thalassaemia: a multi-state Markov model based on national claims data [PDF]
Background Luspatercept is a first-in-class erythroid maturation agent that reduces transfusion burden in adults with transfusion-dependent beta-thalassaemia (TDT). However, its cost-effectiveness has not been evaluated in middle-income settings.
Khachen Kongpakwattana +4 more
doaj +2 more sources
Economic Evaluation of Pneumococcal Vaccination in Egypt: Cost-Effectiveness, Budget Impact, and Domestic Manufacturing Potential [PDF]
Background/Objectives: Streptococcus pneumoniae remains a major cause of morbidity and mortality in Egypt, yet pneumococcal conjugate vaccines (PCVs) are not included in the national immunization program.
Chrissy Bishop +8 more
doaj +2 more sources
The Energy Budgets of Giant Impacts [PDF]
AbstractGiant impacts dominate the final stages of terrestrial planet formation and set the configuration and compositions of the final system of planets. A giant impact is believed to be responsible for the formation of Earth's Moon, but the specific impact parameters are under debate.
Carter, Philip +2 more
openaire +4 more sources
Budget based bonus, budget emphasis, budget gaming, and the impact on budget value [PDF]
The issue of budget value has received attention and criticism from many researchers, especially that the budget value is not aligned with the sacrifices made in the budgeting process. The purpose of the study is to examine the effect of budget-based bonus and budget emphasis towards budget gaming and its implications on budget value.
Rhaisya Setiawati Rachmat, SeTin SeTin
openaire +2 more sources
Emicizumab prophylaxis for people with hemophilia A: Waste estimation and the Brazilian perspective
Costs of hemophilia A treatment are increasing. Waste of clotting products should be avoided. To estimate the first-year waste of emicizumab prophylaxis for people with hemophilia A and inhibitors (PwHAi) who failed immune tolerance induction (ITI), in ...
Ricardo Mesquita Camelo +7 more
doaj +1 more source
Legislations incentivising orphan drug development and scientific advances have made orphan drugs pharma’s high-end favourite for the past two decades. Currently, around 50% of new marketing authorizations are for orphan drugs. For third-party healthcare
Hans-Georg Eichler +3 more
doaj +1 more source
Pharmacoeconomic aspects of macitentan in the therapy of pulmonary arterial hypertension [PDF]
Aim. To provide a pharmacoeconomic estimate of macitentan versus bosentan in therapy for pulmonary arterial hypertension (PAH). Subject and methods. An analysis was carried out on the basis of a social perspective for patients, whose mean age was 50 ...
O M Moisseeva, A V Rudakova
doaj +1 more source
Objectives. To assess the incremental budget impact (BI) of using of utilizing perampanel to treat partial-onset seizures (POS) and primary generalized tonic-clonic seizures (PGTCS) in patients who are 12 years of age and older in Russia.Methods.
V. R. Mkrtchyan +3 more
doaj +1 more source
Aim: to evaluate the pharmacoeconomic efficacy of the application of the atesolizumab (PD-L1 inhibitor) preparation compared with other control point inhibitors (PD-1 inhibitors) in patients with advanced non-small cell lung cancer (NSCLC) after chemothe
S. K. Zyryanov, I. N. Diyakov
doaj +1 more source

