A multiscale Bayesian optimization framework for process and material codesign
Abstract The simultaneous design of processes and enabling materials such as solvents, catalysts, and adsorbents is challenging because molecular‐ and process‐level decisions are strongly interdependent. Sequential approaches often yield suboptimal results since improvements in material properties may not translate into superior process performance. We
Michael Baldea
wiley +1 more source
Implementing home telehealth monitoring in patients with a chronic disease: a budget impact analysis
Gemma Shields, Ann-Marie Chapman
doaj
Accuracy of Budget Impact Projections in Bulgarian Health Technology Assessment: A Five-Year Validation Study (2020-2025). [PDF]
Kostadinov K +5 more
europepmc +1 more source
Trust‐region filter algorithms utilizing Hessian information for gray‐box optimization
Abstract Optimizing industrial processes often involves gray‐box models that couple algebraic glass‐box equations with black‐box components lacking analytic derivatives. Such systems challenge derivative‐based solvers. The classical trust‐region filter (TRF) algorithm provides a robust framework but requires extensive parameter tuning and numerous ...
Gul Hameed +4 more
wiley +1 more source
Balancing innovation and affordability in relapsing-remitting multiple sclerosis: a budget impact analysis from Saudi Arabia. [PDF]
Al-Jedai A +10 more
europepmc +1 more source
A trust‐region funnel algorithm for gray‐box optimization
Abstract Gray‐box optimization, where parts of optimization problems are represented by algebraic models while others are treated as black‐box models lacking analytic derivatives, remains a challenge. Trust‐region (TR) methods provide a robust framework for gray‐box problems through local reduced models (RMs) for black‐box components, but they are ...
Gul Hameed +4 more
wiley +1 more source
Availability, cost, and budget impact of lifesaving postpartum hemorrhage interventions in public hospitals in Zambia: A cross-sectional survey. [PDF]
Kapesa H +5 more
europepmc +1 more source
Abstract Bayesian estimation enables uncertainty quantification, but analytical implementation is often intractable. As an approximate approach, the Markov Chain Monte Carlo (MCMC) method is widely used, though it entails a high computational cost due to frequent evaluations of the likelihood function.
Tatsuki Maruchi +2 more
wiley +1 more source
Budget Impact Analysis of Lebrikizumab for Treating Severe Atopic Dermatitis. [PDF]
Antonazzo IC +6 more
europepmc +1 more source
Graph‐based imitation and reinforcement learning for efficient Benders decomposition
Abstract This work introduces an end‐to‐end graph‐based agent for accelerating the computational efficiency of Benders Decomposition. The agent's policy is parameterized by a graph neural network, which takes as input a bipartite graph representation of the master problem and proposes a candidate solution.
Bernard T. Agyeman +3 more
wiley +1 more source

