Results 111 to 120 of about 190,629 (301)

Targeting the CMKLR1‐Mediated Signaling Rebalances Immunometabolism State in Middle‐Age Testicular Macrophages

open access: yesAdvanced Science, EarlyView.
In middle age, testicular CMKLR1⁺ macrophages exhibited a pro‐inflammatory immunometabolic profile, mediated by adipose signals associated with high BMI. However, inhibition of CMKLR1 signaling, either through Cmklr1 genetic ablation or treatment with a CMKLR1 antagonist peptide, can reverse this phenotype.
Zhendong Zhu   +10 more
wiley   +1 more source

Evaluation of innovative potential of health care institutions on the example of children's city clinical hospital in megalopolis

open access: yesRUDN Journal of Medicine, 2015
This article is devoted to the definition and evaluation of innovative potential of the organization of the health system. For assessment of innovative potential of budgetary organization it is necessary to carry out a complex assessment of the following
A V Bullikh   +3 more
doaj  

Finance Ministry of Defense and Serbian Army own revenues [PDF]

open access: yesOditor, 2017
By October 2012, funds its activities or the sale of goods and provision of services realized entities in the Ministry of Defense and the Serbian Army had its own treatment of revenue and accounted for as a separate source of funding, of which the ...
Stoilkov Velibor, Ivanova Biljana
doaj  

Limits of Conditionality in Poverty Reduction Programs [PDF]

open access: yes
When donors and recipients have different preferences over budgetary allocations, conditionality helps the implementation of donor-financed poverty reduction programs.
Giovanni Dell'Aricca, Tito Cordella
core  

From Natural Discovery to AI‐Guided Design: A Curated Collection of Compact Enhancers for Crop Engineering

open access: yesAdvanced Science, EarlyView.
ABSTRACT Precise transgene‐free gene upregulation remains a challenge in crop biotechnology, as conventional enhancers often exceed CRISPR‐mediated knock‐in size constraints and face regulatory hurdles. Here we establish a foundational cross‐species resource of compact transcriptional enhancers developed via STEM‐seq, a high‐throughput screening ...
Qi Yao   +14 more
wiley   +1 more source

New Budget, New Regulations, New Strategies : the 2006 Reform of EU Cohesion Policy [PDF]

open access: yes, 2007
Examines the reform of EU cohesion policy in ...
Bachtler, John   +2 more
core  

Durable Thin‐Film Porous Transport Electrodes for High Current Density PEM Water Electrolysis

open access: yesAdvanced Science, EarlyView.
Water electrolysis using porous transport electrodes with sputter‐deposited, ionomer‐free thin films of rutile IrO2 catalyst suppresses Ir dissolution by >10x over other forms of IrOx. The rutile IrO2 catalyst prepared by this readily scalable electrode synthesis method provides stable cell operation at 3 A cm−2 while using low Ir loading (0.4 mg Ir cm−
James L. Young   +18 more
wiley   +1 more source

AI‐Based D‐Amino Acid Substitution for Optimizing Antimicrobial Peptides to Treat Multidrug‐Resistant Bacterial Infection

open access: yesAdvanced Science, EarlyView.
This study constructed the first D‐amino acid antimicrobial peptide dataset and developed an AI model for efficient screening of substitution sites, with 80% of candidate peptides showing enhanced activity. The lead peptide dR2‐1 demonstrated potent antimicrobial activity in vitro and in vivo, high stability, and low toxicity.
Yinuo Zhao   +14 more
wiley   +1 more source

The governance of domestic fiscal stability in the Eurozone prior to the financial crises (2000-2007): What lessons for implementation of the TSCG? [PDF]

open access: yes, 2012
After its first thorough revision in 2005, the Stability & Growth Pact (SGP) has recently been transformed into a Fiscal Stability Treaty, which in all likelihood will become operational as from January 1, 2013.
Donnelly, S., Groenendijk, N.S.
core   +2 more sources

Home - About - Disclaimer - Privacy