Results 31 to 40 of about 10,484 (264)
Structure‐forward targeting of claudins with synthetic binders
Claudins form the paracellular barriers between epithelial and endothelial tissues at tight junctions and are targets for molecular binders with the goal of modulating barrier permeability. Claudin‐binding molecules are relevant in drug delivery or in altering claudin interactions with disease‐causing proteins.
Alex J. Vecchio
wiley +1 more source
A Depolarizing Leak in Sodium Bicarbonate Cotransporter NBCe1 Causes Brain Edema
ABSTRACT Objectives SLC4A4 encodes electrogenic sodium bicarbonate cotransporter NBCe1, prominently expressed in kidney and brain. Recessive loss‐of‐function variants in SLC4A4 cause proximal renal tubular acidosis, no brain edema. In the brain, NBCe1 is expressed by astrocytes, where it regulates pH and mediates astrocyte volume changes.
Quinty Bisseling +16 more
wiley +1 more source
This study was designed to deduce the inter-relationship between external genitalia measurement, antral follicular count (AFC) and body weight (BW) and evaluate estrus induction rate following the administration of clomiphene citrate in pre-pubertal ...
JEROME A +4 more
doaj +1 more source
Functional genome profiling of Murrah buffaloes (Bubalus bubalis) was performed for milk-production trait by whole blood transcriptome analysis comparing RNA-seq data assembled from high and low milk producing multiparous (5 -6 parity) animals.
Poonam Sikka +9 more
doaj +1 more source
ABSTRACT Introduction/Objective Acute intracranial stenting during endovascular thrombectomy (EVT) for ischemic stroke requires intraprocedural antiplatelet therapy (APT) to maintain patency. However, the hemorrhagic risk of combining APT with intravenous thrombolysis (IVT) remains uncertain.
Aaron Rodriguez‐Calienes +75 more
wiley +1 more source
Selection of high producing dairy animals is important for dairy profitability and future breeding stock. The farmers have relied on physical characters for identification of milk producing ability in animals.
Sunesh Balhara +5 more
doaj +1 more source
Atomic layer deposition is used to conformally surface engineer polymeric membranes to fabricate inorganic–organic hybrid membranes. These membranes have exceptionally strong attraction toward water even in high oil containing emulsions, which leads to an extremely strong hydration layer at the interface.
Bratin Sengupta +8 more
wiley +1 more source
AMH had no correlation with AFC and BW, but AFC was correlated with BW in high antral follicular group heifers. Furthermore, this study shows that AMH exhibited a trend with AFC in peri-pubertal buffalo heifers.
K M KAVYA +4 more
doaj +1 more source
A controlled layer‐by‐layer growth process integrates conjugated metal‐organic framework thin films onto a hierarchical 3D laser‐induced graphene scaffold. When incorporated into an extended‐gate field‐effect transistor configuration, this synergistic hybrid platform achieves robust aptamer immobilization, driving highly selective, picomolar‐level ...
Khanh T. M. Le +2 more
wiley +1 more source
To investigate the effect of pre-partum heifer management on udder and teat development, temperament score, milking traits, milk yield and composition, 12 primiparous Nili-Ravi buffaloes from ICAR-CIRB, Nabha Buffalo Farm were enrolled. All experimental
KALYAN SUNDAR DAS +2 more
doaj +1 more source

