Results 91 to 100 of about 4,351,429 (251)

Lysis-buffer-treated versus intact plaques.

, 2019
H&E staining of s- and v-plaques on shows elimination of plaque surface cells (arrows) after lysis-buffer treatment.
Zhanna K. Nazarkina (6883388), Ivan S. Murashov (6883400), Evgeny A. Pokushalov (3234756), Olga A. Novikova (6883385), Petr P. Laktionov (6883394), Andrey A. Karpenko (6883406), Boris P. Chelobanov (6883397), Pavel P. Laktionov (2565487), Anna V. Cherepanova (6883391), Roman V. Deev (6883403)   +9 more
core   +1 more source

Circular RNA expression landscapes in myelodysplastic neoplasms: Associations with mutational signatures and disease progression

Molecular Oncology, EarlyView.
In this explorative study, the abundance of circular RNA molecules in bone marrow stem cells was found to be elevated in patients with high‐risk myelodysplastic neoplasms, and to be associated with an increased risk of progression to acute myeloid leukemia.
Eileen Wedge, Morten Tulstrup, Gabriele Todisco, Pedro Moura, Christophe Côme, Jakob Werner Hansen, Jakob Schmidt Jespersen, Balthasar Schlotmann, Maria Creignou, Mette Dahl, Claudia Schöllkopf, Klas Raaschou‐Jensen, Krister Wennerberg, Bo Porse, Joachim Weischenfeldt, Eva Hellström‐Lindberg, Lasse Sommer Kristensen, Kirsten Grønbæk   +17 more
wiley   +1 more source

Calculation of the transmission peak at the band gap of one-dimensional photonic crystal with an active layer

Учёные записки Казанского университета: Серия Физико-математические науки, 2018
Tamm plasmons (TP) attract interest due to their applications in a new type of lasers and high sensitivity sensors. Hybrid plasmonic-photonic crystals allow direct excitation of TP without prisms and gratings.
A.V. Koryukin
doaj  

The riparian zone quality index: a tool for monitoring environmental regulations and raising awareness

VertigO
In Quebec, due to climate change, the provincial government established a Policy for the Protection of Shorelines, Littoral Zones, and Floodplains in 1987.
Richard Massicotte
doaj   +1 more source

IMPDH inhibition enhances cytarabine efficacy in SAMHD1‐expressing leukaemia cells via guanine nucleotide depletion

Molecular Oncology, EarlyView.
Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla, Christopher Dirks, Caroline Eiden, Sonja K. Fesenmayer, Femke M. Hormann, Yolande Klootsema, Ingrid Lilienthal, Si Min Zhang, Nikolas Herold, Sean G. Rudd   +9 more
wiley   +1 more source

Stimulator of interferon genes agonist augmented antitumor immunity of osimertinib in Egfr‐mutated lung cancer

Molecular Oncology, EarlyView.
Combining osimertinib with the STING agonist ADU‐S100 activates innate and adaptive immunity to overcome the non‐inflamed microenvironment of Egfr‐mutant lung cancer. This combination increases NK and CD8+ T‐cell infiltration, associated with activation of the STING‐IRF3 pathway and local immunogenic cell death.
Jun Nishimura, Tadahiro Kuribayashi, Johannes Brägelmann, Sachi Okawa, Masataka Taoka, Shunta Mori, Tomoka Nishimura, Takaaki Tanaka, Go Makimoto, Kiichiro Ninomiya, Kammei Rai, Eiki Ichihara, Ryohei Katayama, Katsuyuki Hotta, Masahiro Tabata, Yosuke Togashi, Yoshinobu Maeda, Martin L. Sos, Katsuyuki Kiura, Kadoaki Ohashi   +19 more
wiley   +1 more source

Buffer-compositions for HP1542 low spin down assay.

, 2019
Buffer-compositions for HP1542 low spin down assay.
Barbara Waidner (256992), Frank Noll (2540209), Sven Holtrup (6871598), Thomas Heimerl (211423), Florian Altegoer (460663), Uwe Linne (711487)   +5 more
core   +1 more source

Loss of IGF‐1R impairs DNA‐PKcs recruitment to chromatin leading to defective end‐joining

Molecular Oncology, EarlyView.
IGF‐1R promotes radioresistance by facilitating DNA‐PKcs recruitment to chromatin, enabling non‐homologous end‐joining (NHEJ) repair of double‐strand breaks. Inhibition or loss of IGF‐1R disrupts this recruitment to damage sites, driving compensatory reliance on microhomology‐mediated end‐joining (MMEJ) repair.
Matthew O. Ellis, Jack V. Mills, Wojciech Niedzwiedz, Valentine M. Macaulay   +3 more
wiley   +1 more source

Buffer Block Planning for Interconnect-Driven Floorplanning

, 2008
This paper studies buffer block planning for interconnect-driven floorplanning in deep submicron designs. We first introduce the concept of feasible region (FR) for buffer insertion, and derive closed-form formula for FR.
Jason Cong Tianming, Planning Interconnect-driven Floorplanning, Buffer Block   +2 more
core  

Spatial mapping of optical constants and thickness variations in ITO films and SiO2 buffer layers

Optical Materials: X
In this work, we present detailed spectroscopic ellipsometry (SE) measurements across thirty indium tin oxide In2O3–SnO2 (ITO) substrates, providing insights into variations in the complex refractive index N˜ for the same commercial ITO material.
I. Aulika, P. Paulsone, E. Laizane, J. Butikova, A. Vembris   +4 more
doaj   +1 more source