Results 51 to 60 of about 382,121 (363)
FEBS Letters, EarlyView.Spinal muscular atrophy (SMA) is a genetic disease affecting motor neurons. Individuals with SMA experience mitochondrial dysfunction and oxidative stress. The aim of the study was to investigate the effect of an antioxidant and neuroprotective substance, ergothioneine (ERGO), on an SMNΔ7 mouse model of SMA.
Francesca Cadile +8 more
wiley +1 more source
Comparative analysis of protocols for decellularization of corneal lenticular tissue
Вестник трансплантологии и искусственных органов, 2021 Shortage of donor corneas is a burning issue in ophthalmology. That is why there is a search for new alternative ways for treating corneal diseases. Decellularization technologies make it possible to create corneal tissue-engineered constructs that can ...
S. A. Borzenok +6 more
doaj +1 more source
Astronomical Telescopes + Instrumentation, 2018 The Gemini High-Resolution Optical SpecTrograph (GHOST) is the newest instrument being developed for the Gemini telescopes, in a collaboration between the Australian Astronomical Observatory (AAO), the Herzberg Institute for Astrophysics, National ...
V. Churilov +9 more
semanticscholar +1 more source
Molecular Oncology, EarlyView.Carcinoma‐associated fibroblasts (CAFs) in tumors influence cancer progression. We identified endoglin (ENG) as a key factor in TGF‐β signaling in myofibroblastic CAFs (myCAFs), linked to poor breast cancer outcomes. Inhibiting ENG on myCAFs suppressed the TGF‐β‐Smad2/3 pathway, reducing primary tumor growth and metastasis.
Shoki Okubo +11 more
wiley +1 more source
Journal of Applied Oral Science, 2022 Quantification of collagen degradation is an important parameter to evaluate dentin caries for preventive aid. Objectives: Evaluate preventive methods against root collagen degradation by the hydroxyproline assay (HYP) and microradiography technique ...
Andrea Maselli +6 more
doaj +1 more source
, 2013 We developed an apparatus to couple a 50-micrometer diameter whispering-gallery silica microtoroidal resonator in a helium-4 cryostat using a straight optical tapered-fiber at 1550nm wavelength.
Arcizet, O. +3 more
core +1 more source
FEBS Open Bio, EarlyView.In this research, a rat model of asthma was created using OVA, and polydatin served as an intervention. By inhibiting ferroautophagy mediated by NCOA4 and averting ferroptosis, polydatin has been demonstrated to reduce asthma. This work presents new ideas for investigating the mechanism of polydatin's ability to alleviate asthma, in addition to ...
Wei Li +5 more
wiley +1 more source
Concept level evaluation of the optical voltage and current sensors and an arrayed waveguide grating for aero-electrical system applications [PDF]
, 2007 In this paper we present, for the first time, the hybrid fiber-optic voltage and current sensors interrogated using an arrayed waveguide grating (AWG) device.
Fusiek, G., McDonald, J.R., Niewczas, P.
core +1 more source
Repeat Expansions in PLIN4 Cause Autosomal Dominant Vacuolar Myopathy With Sarcolemmal Features
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective We aim to describe and characterize two unrelated Spanish families suffering from an autosomal dominant autophagic vacuolar myopathy caused by repeat expansions in PLIN4. Methods We evaluated the clinical phenotype and muscle imaging, and performed a genetic workup that included exome sequencing, muscle RNAseq, and long‐read genome ...
Laura Llansó +17 more
wiley +1 more source
PhotonicsWe demonstrate a low latency delay of a radio frequency (RF)–linear frequency-modulated (LFM) pulse by modulating it onto optical carriers from a Kerr comb and sending the signal through a concatenation of off-the-shelf linearly chirped fiber Bragg ...
Ahmed Almaiman +4 more
doaj +1 more source