Results 161 to 170 of about 18,176,359 (256)

Residential Greenspace and Domestic Gardens, Genetic Predisposition, and Incident Glaucoma: A Prospective Cohort Study. [PDF]

Geohealth
Zhang X, Han C, Liu X, Lu T, Zhang Z, Zhu X, Huang Y, Li C, Xu X, Sun Y, Zhao S, Zheng Z.   +11 more
europepmc   +1 more source

Treatment with KCL‐286, a first‐in‐class retinoic acid receptor‐β (RARβ) agonist, ameliorates neuronal DNA damage and inflammation in a mouse model of Alzheimer's disease

FEBS Open Bio, EarlyView.
Repair of neuronal DNA damage in Alzheimer's disease by KCL‐286. (A) Amyloid‐β oligomers and plaques impair neuronal DNA repair pathways, leading to DNA double‐strand breaks and glial activation. (B) KCL‐286 activates RARβ/RXR signalling via retinoic acid response elements (RAREs), associated with increased BRCA1 expression, enhanced DNA repair and ...
Natasha Hill, Hassan Yousef Othman AlMuallim, Elouisa Maddock, Carl Hobbs, Earl Clarke, Maria B. Goncalves, Jonathan P. T. Corcoran   +6 more
wiley   +1 more source

Protocol for high-resolution multiplexed sequencing of single-cell full-length transcriptome with CBTi-seq. [PDF]

STAR Protoc
He L, Zhang W, Qi P, Jiao Z, Zhang D, Zhao X.   +5 more
europepmc   +1 more source

Yeast Gcn2 retains activity following humanization of its auto‐phosphorylation region

FEBS Open Bio, EarlyView.
Using Saccharomyces cerevisiae as a model to study Gcn2 activation and regulation is limited by the lack of antibodies detecting phosphorylated Gcn2. To overcome this, we engineered Gcn2‐HsC, a yeast Gcn2 variant recognizable by commercial anti‐human phospho‐GCN2 antibodies.
Reuben A. Anderson, Anja H. Schiemann, Evelyn Sattlegger   +2 more
wiley   +1 more source

Comparative review of glycated albumin detection from conventional colorimetric assays to Raman spectroscopy, surface-enhanced Raman scattering, and surface plasmon resonance. [PDF]

RSC Adv
Jayasekara LASP, Senadeera SPNN, Samarathunga LM, Priyashantha PRTD, Kottahachchi DU, Ranaweera CB.   +5 more
europepmc   +1 more source

Effect of terahertz irradiation on DNA damage repair in living cells

FEBS Open Bio, EarlyView.
We investigated the effect of terahertz (THz) wave irradiation on DNA double‐strand break (DSB) repair in living cells. We found that THz irradiation enhanced DSB repair at specific frequencies, whereas heat treatment inhibited it, indicating that this effect is nonthermal and frequency‐specific.
Yuya Ueno, Shota Yamazaki, Hiromichi Hoshina, Masahiko Harata   +3 more
wiley   +1 more source

Methodology for preventing Botulinum toxin-A eyelid ptosis: Risk index derivation, safety rules, and evidence-graded management algorithm. [PDF]

World J Methodol
Diab N, Bou Farah E, Berjawi A, Ghorayeb T, Beydoun K, Ghanem S, Hamou A, Tarchichi A, Tlaiss Y.   +8 more
europepmc   +1 more source

Importin 7 mediates the nuclear import of HIV‐1 integrase via a specific interacting interface

FEBS Open Bio, EarlyView.
HIV‐1 integrase enables viral DNA integration into the host genome. By binding to the core domain of the host protein Importin 7 via its C‐terminal domain, the integrase is transported across the nuclear membrane into the nucleus, where integration of the viral genome into host DNA takes place. This translocation is a critical step for subsequent viral
Juana Bana, Avigail Yariv, Tal Oppenheim, Hadar Amartely, Dana Reichmann, Oded Livnah   +5 more
wiley   +1 more source

Development of a network buffer for a Quantum Random Number Generator

openQuesta tesi presenta lo sviluppo di un buffer di rete generalizzato per la distribuzione in tempo reale degli eventi generati da un QRNG (Quantum Random Number Generator) e acquisiti tramite tre timetagger diversi (fake, quTAG, Swabian). Inizialmente
GOBBO, LORENZO KAROL
core  

Periodontal Disease Diagnosis by a Chemically Etched Single-Mode Fiber-Optic Biosensor for Label-Free Detection of Matrix Metalloproteinase-8 (MMP-8). [PDF]

Biosensors (Basel)
Tovar R, Sozkes S, Sypabekova M.
europepmc   +1 more source