Results 221 to 230 of about 18,176,359 (256)

Stability of Medicinal Nanoemulsions to Spaceflight: Insights From the StarMed Experiment. [PDF]

Adv Healthc Mater
Adebowale M, Long NVD, Williams PM, Hauslage J, Hessel V.   +4 more
europepmc   +1 more source

Genetic dissection of human ABCE1 in yeast reveals separable requirements for ribosome recycling and suppression of aberrant reinitiation

FEBS Open Bio, EarlyView.
Human ABCE1 cannot functionally replace its yeast ortholog. Yeast–human chimera analysis identified NBD1 as a major interspecies barrier. Genetic screening yielded hABCE1 revertants that rescue yeast viability but fail to suppress aberrant translation reinitiation in the 3′ UTR.
Eriko Nakata, Yuxin Li, Kei Endo, Koichi Ito   +3 more
wiley   +1 more source

Near-Real Time Monitoring of Active Volcanoes from Space Using SLSTR (Sea and Land Surface Temperature Radiometer) SWIR (Shortwave Infrared) Observations. [PDF]

Sensors (Basel)
Filizzola C, Mazzeo G, Genzano N, Pietrapertosa C, Marchese F.   +4 more
europepmc   +1 more source

MARK4 enhances stress granule formation under oxidative stress and increases tau accumulation

FEBS Open Bio, EarlyView.
MARK4 (red dots) localizes to stress granules (orange dots) and promotes their formation under oxidative stress by modulating TIA1 (blue dots). MARK4 and TIA1 synergistically increase tau (purple) accumulation, and the reduction of the TIA1 ortholog suppresses neurodegeneration in a fly model.
Sho Nakajima, Kotone Watanabe, Grigorii Sultanakhmetov, Aoi Fukuchi, Keiya Ito, Sawako Shimizu, Taro Saito, Akiko Asada, Kanae Ando   +8 more
wiley   +1 more source

Infection and α-ketoglutarate/oxygen inhibition converge to CDC20 to promote cancer cell aneuploidy. [PDF]

Signal Transduct Target Ther
Zhou YN, Xu FJ, Yao CF, Li Y, He YS, Ma ZZ, Yang SY, Tong X, Lin Y, Yuan YY, Zhao JY, Lin PC, Mao YZ, Kang Y, Zhao SM, Xu W.   +15 more
europepmc   +1 more source

IGF2 knockout reduces but does not abolish osteosarcoma growth in vitro and in vivo

FEBS Open Bio, EarlyView.
To test whether endogenous IGF2 promotes osteosarcoma growth, IGF2 was knocked out in Saos2 cells via CRISPR‐Cas9. KO cells showed reduced proliferation in vitro, and knockout xenografts in mice reached only ~25% of wild‐type tumor volume. Insulin‐like growth factor 2 (IGF2) is implicated in osteosarcoma, but direct functional evidence of its role is ...
Shun Yao, Marco Archetti
wiley   +1 more source

Association between residential greenness and preeclampsia in Japan. [PDF]

Environ Epidemiol
Ohseto H, Uematsu A, Ishikuro M, Xian Z, Takahashi Y, Orui M, Murakami K, Noda A, Shinoda G, Chen G, Iwama N, Kikuya M, Metoki H, Hozawa A, Obara T, Nakaya T, Kuriyama S.   +16 more
europepmc   +1 more source

Type I interferons modulate autophagy to shape gemcitabine response in pancreatic cancer cells

FEBS Open Bio, EarlyView.
Type I interferons differentially modulate autophagy and the response of pancreatic cancer cells to gemcitabine. IFNα2b stimulates autophagic flux and protects cells from gemcitabine‐induced cell death, contributing to chemoresistance. In contrast, IFNβ1a inhibits autophagosome formation and enhances gemcitabine‐induced cell death, resulting in ...
Lucy E. Bonilla, Martín M. Ledesma, Santiago A. Behr, Matías A. Pibuel, María L. Palanek, Daniel H. Grasso, Maria N. Garcia, Juan Garona, Silvina L. Lompardía, Elida Álvarez, Daniela L. Papademetrio   +10 more
wiley   +1 more source

ACSCull: visibility-aware triangle elimination for skinned characters under an admissible Camera Set. [PDF]

MethodsX
Tarigan JT.
europepmc   +1 more source