Advanced Science, EarlyView.ABSTRACT Astrocyte reactivity critically shapes neuroinflammatory outcomes after ischemic stroke, yet the upstream regulators governing astrocyte state transitions remain incompletely defined. Here, we identify the immunoproteasome subunit low molecular weight protein 2 (LMP2) as an important modulator of astrocyte functional remodeling following ...
Yanguang Mao +7 more
wiley +1 more source
Growth-Pathway-Controlled van der Waals Epitaxy of Phase-Selective Tin Sulfides. [PDF]
Adv Sci (Weinh)Lee J, Kim J, Lee GH.
europepmc +1 more source
Engineering of Crystal and Domain Structures in Epitaxial Y:HfO2 Thin Films by YSZ Substrate Miscut
Advanced Science, EarlyView.We investigate how YSZ substrate miscut influences crystal structure and domain formation in epitaxial Y‐doped HfO2 thin films. Using magnetron sputtering, high‐resolution X‐ray diffraction, atomic‐resolution scanning transmission electron microscopy, and first‐principles calculations, we systematically examine the characteristics of thickness‐ and ...
Jun Young Lee +12 more
wiley +1 more source
On-Demand Viscosity Gradients Turn Nanoliter Droplets into Programmable Sources of Enriched Picoliter Droplets. [PDF]
J Am Chem SocEdirisinghe SJ, Anand RK.
europepmc +1 more source
Friend, Not Foe: Lowered Tissue Reactivity to Long‐Term Polyimide Implants
Advanced Science, EarlyView.The choice of optimal neural probe designs remains a major challenge in the field of neurotechnology. This study investigated the biocompatibility of several probe variations, including material, thickness, width, and implantation strategy. It highlights the clear advantage of soft polyimide probes over stiff silicon probes for better device ...
Corinne Orlemann +11 more
wiley +1 more source
Modular reconfiguration and actuation of microrobotic assemblies. [PDF]
iScienceSharma PK, Lu TY, Chen CY.
europepmc +1 more source
Harnessing Phase Separation for the Development of High‐Performance Hydrogels
Advanced Science, EarlyView.ABSTRACT Hydrogels are indispensable for the development of next‐generation bioelectronics, soft robotics, and biomedical devices, where their mechanical properties determine performance and reliability. Among strategies to enhance hydrogel mechanics, phase separation enables controlled heterogeneity resulting in gel networks that are reinforced by ...
Yue Shao +3 more
wiley +1 more source
Proteomic dynamics in endochondral ossification: insights from antler tip analysis. [PDF]
PeerJXi X +8 more
europepmc +1 more source
Advanced Science, EarlyView.We demonstrate a novel therapy for traumatic brain injury TBI using a LIPUS‐responsive Piezoelectric fibrous membrane. It targets microglial mitochondria via in situ electrical signals, restoring homeostasis and reducing oxidative stress to promote an anti‐inflammatory M2 phenotype.
Wei Li +9 more
wiley +1 more source
A Modified Slide-Embedded Scanning Electron Microscopy Preparation Method to Visualize Antagonistic Interactions Between <i>Trichoderma viride</i> and <i>Fusarium</i> sp. [PDF]
Bio ProtocTomichen S, Panchal S.
europepmc +1 more source