Results 41 to 50 of about 1,606,799 (302)
Leucine‐rich glioma inactivated 1 (LGI1) is a ganglioside‐binding protein
FEBS Letters, EarlyView.Neuronal hyperexcitability associated with a decrease/absence of the extracellular protein LGI1 has been suggested to be primarily due to the downregulation of Kv1 channel expression. The molecular mechanisms underlying this decrease have not yet been elucidated.
Kévin Debreux +7 more
wiley +1 more source
Molecular Oncology, EarlyView.The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka +9 more
wiley +1 more source
FUUAST Journal of Biology, 2012 The growth of Albizia lebbeck (L.) Benth., were studied in soils collected from Khan Towel, Tanveer Garment, One Tech Rubber and One Tech Ply Board factories in the vicinity of Korangi and Landhi industrial sites under natural environmental conditions ...
SYED ATIQ-UR-RAHMAN +1 more
doaj
Investigation of the Effect of Soil Moisture in the Sub-root Zone Layer on Water Uptake Amount in Three Different Soil Textures [PDF]
رویکردهای نوین در مهندسی آب و محیط زیستChanging in precipitation pattern and incidence drought stress shows the necessity of optimal use of water resources and saving in consumption is emerged more than before.
Masoud Soltani +2 more
doaj +1 more source
Molecular Oncology, EarlyView.Matched spatial transcriptomics and single‐nuclei RNA‐seq were generated for anaplastic and BRAFV600E papillary thyroid cancers revealing generic and tumor‐specific states occurring in cancer cells and in the tumor microenvironment. In this context, cancer dedifferentiation mirrored organoid maturation through ordered thyroid marker gain/loss ...
Adrien Tourneur +11 more
wiley +1 more source
Environmental and Sustainability IndicatorsSolid success in conserving the protected areas would obviously require the participation and cooperation from local people particularly in developing countries where the locals bear most of the expense of Human wildlife co-existence.
Dipesh Raj Pant +4 more
doaj +1 more source
Molecular Oncology, EarlyView.We established the avian chorioallantoic membrane (CAM) assay as a scalable in vivo model for studying circulating tumor cells (CTCs). Human gastrointestinal tumors spontaneously released genetically validated CTCs that were detected across multiple platforms, demonstrating that the CAM model provides an accessible tool for investigating early cancer ...
Dennis Roth +17 more
wiley +1 more source
Functional zoning of China's protected area needs to be optimized for protecting giant panda
Global Ecology and Conservation, 2021 Management zone designations are important to improving the core function of biodiversity conservation in any protected area. However, land managers of most protected areas can barely identify whether the zones they manage are ideally designated due to ...
Hongfei Zhuang +7 more
doaj +1 more source
ATZ‐1 promotes DNA replication efficiency to maintain normal meiotic function
FEBS Open Bio, EarlyView.Absence of ATZ‐1 interferes with meiotic DNA replication and cell cycle function via CHK‐1. This causes downstream defects associated with DNA damage and genomic integrity. Taken together, this study suggests that ATZ‐1 influences DNA replication efficiency and cell cycle function to maintain normal meiotic function.
Taylin E. Gourley +5 more
wiley +1 more source
Buffer zone use by mammals in a Cerrado protected area [PDF]
, 2016 Habitat loss and degradation is threatening mammals worldwide. Therefore, Protected Areas (PA) are of utmost importance to preserve biodiversity. Their effectiveness, however, depends on some management strategies such as buffer zones, which prevent ...
Pasqualotto, Nielson +12 more
core +1 more source