Results 11 to 20 of about 153 (97)

Harnessing the Natural Toxic Metabolites in COVID-19. [PDF]

open access: yesEvid Based Complement Alternat Med, 2022
SARS‐CoV‐2 is a novel coronavirus and the cause of the recent pandemic; it is an enveloped β‐coronavirus. SARS‐CoV‐2 appear in the Wuhan City of China for the first time and outspread worldwide quickly. Due to its person‐to‐person fast transmission, COVID‐19 is becoming a global problem.
Bahrami A   +9 more
europepmc   +2 more sources

The clinical pharmacology and potential therapeutic applications of 5-methoxy-N,N-dimethyltryptamine (5-MeO-DMT). [PDF]

open access: yesJ Neurochem, 2022
5‐methoxy‐N,N‐dimethyltryptamine (5‐MeO‐DMT) is a naturally occurring tryptamine that primarily acts as an agonist at the 5‐HT1A and 5‐HT2A receptors, whereby affinity for the 5‐HT1A subtype is highest. Studies have suggested that single exposure to 5‐MeO‐DMT can cause rapid and sustained reductions in symptoms of depression, anxiety, and stress. 5‐MeO‐
Reckweg JT   +6 more
europepmc   +2 more sources

Investigating the Multitarget Mechanism of Traditional Chinese Medicine Prescription for Cancer-Related Pain by Using Network Pharmacology and Molecular Docking Approach. [PDF]

open access: yesEvid Based Complement Alternat Med, 2020
Gu‐tong formula (GTF) has achieved good curative effects in the treatment of cancer‐related pain. However, its potential mechanisms have not been explored. We used network pharmacology and molecular docking to investigate the molecular mechanism and the effective compounds of the prescription.
Chang J   +5 more
europepmc   +2 more sources

The dark web trades wildlife, but mostly for use as drugs

open access: yesPeople and Nature, Volume 5, Issue 3, Page 999-1009, June 2023., 2023
Abstract Contemporary wildlife trade is massively facilitated by the Internet. By design, the dark web is one layer of the Internet that is difficult to monitor and continues to lack thorough investigation. Here, we accessed a comprehensive database of dark web marketplaces to search across c. 2 million dark web advertisements over 5 years using c. 7 k
Oliver C. Stringham   +14 more
wiley   +1 more source

A retrospective study of cane toad (Rhinella marina) toxicity in 190 domestic cats in Southeastern Queensland: Clinical presentations, treatments, and outcomes

open access: yesAustralian Veterinary Journal, Volume 101, Issue 6, Page 219-224, June 2023., 2023
Objective To report the clinical presentations, treatments and outcomes of toad toxicity in domestic cats in Southeastern Queensland, Australia. Methods This report describes a retrospective study of 190 cases of cane toad (Rhinella marina) toxicity in cats in south‐eastern Queensland, Australia.
OS Leong   +3 more
wiley   +1 more source

Add-On Therapy with Traditional Chinese Medicine Improves Outcomes and Reduces Adverse Events in Hepatocellular Carcinoma: A Meta-Analysis of Randomized Controlled Trials. [PDF]

open access: yesEvid Based Complement Alternat Med, 2017
Background and Aims. Traditional Chinese medicine (TCM) therapy for hepatocellular carcinoma remains controversial. This study aimed to evaluate the efficacy and safety of TCM regimens in HCC treatment. Methods. Randomized controlled trials (RCTs) up to June 1, 2016, of the TCM treatment for hepatocellular carcinoma were systematically identified in ...
Yang Z   +6 more
europepmc   +2 more sources

Impact of the Aversive Effects of Drugs on Their Use and Abuse

open access: yesBehavioural Neurology, Volume 2022, Issue 1, 2022., 2022
Drug use and abuse are complex issues in that the basis of each may involve different determinants and consequences, and the transition from one to the other may be equally multifaceted. A recent model of the addiction cycle (as proposed by Koob and his colleagues) illustrates how drug‐taking patterns transition from impulsive (acute use) to compulsive
Anthony L. Riley   +3 more
wiley   +1 more source

Trophic structure of a pond community dominated by an invasive alien species: Insights from stomach content and stable isotope analyses

open access: yesAquatic Conservation: Marine and Freshwater Ecosystems, Volume 31, Issue 4, Page 948-963, April 2021., 2021
Abstract Invaders affect native species across multiple trophic levels, influencing the structure and stability of freshwater communities. Based on the ‘trophic position hypothesis’, invaders at the top of the food web are more harmful to native species via direct and indirect effects than trophically analogous native predators are. However, introduced
Alessandra Maria Bissattini   +10 more
wiley   +1 more source

Sex and weaponry: The distribution of toxin-storage glands on the bodies of male and female cane toads (Rhinella marina). [PDF]

open access: yesEcol Evol, 2017
Male and female cane toads differ in the distribution of toxin‐containing glands in different areas of the body. That divergence may reflect ecological and behavioral differences that have acted as selective forces on toxin‐gland location. Abstract The parotoid macroglands of bufonid anurans store (and can expel) large volumes of toxic secretions and ...
Chen W, Hudson CM, DeVore JL, Shine R.
europepmc   +2 more sources

Toad poisoning in three dogs: case reports

open access: yesJournal of Venomous Animals and Toxins including Tropical Diseases, 2009
Toad poisoning is frequent in dogs, but has been infrequently addressed in published case reports and review articles. Dogs can be poisoned when they bite a toad or otherwise ingest the venom. The venom effects manifest soon after the accident, since the
CM Barbosa   +4 more
doaj   +1 more source

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