Results 201 to 210 of about 28,472 (266)

Intrinsically Mitochondria‐Targeting Nanozyme via Coordination‐Assembly of Natural Quercetin for Cascade Antioxidant Therapy of Cerebral Ischemia‐Reperfusion Injury

Advanced Science, EarlyView.
This study uncovers that quercetin naturally targets mitochondria. By coordinating quercetin with Fe3+, we engineer an ultrasmall cascade nanozyme (MCN) with superoxide dismutase‐catalase activities. MCN crosses the damaged blood–brain barrier, scavenges mitochondrial ROS, prevents mitochondrial DNA leakage, and blocks the cGAS‐STING pathway, thereby ...
Wenxuan Zheng, Zhicheng Wang, Xin Zhou, Shuya Wang, Xiaojing Shi, Tingli Xiong, Ruishi Li, Yuting Lin, Zhen Chen, Jiawen Wei, Fei Li, Jinwen Ge, Kelong Ai, Chong Liu, Guiming Deng   +14 more
wiley   +1 more source

Evaluating LLM Integration in Pharmacometrics Through a Software Development Perspective. [PDF]

J Pediatr Pharmacol Ther
Barrett K, Callisto SP.
europepmc   +1 more source

Pharmacological Inhibition of FKBP51 Mitigates Early Life Adversity‐Induced Social Deficits in Male Mice

Advanced Science, EarlyView.
Early life adversity triggers persistent social subordination and brain‐wide molecular dysregulation. Pharmacological inhibition of the stress‐mediator FKBP51 during the adversity period prevents these long‐term deficits and restores normative social hierarchy.
Joeri Bordes, Xiuqi Ji, Serena Gasperoni, Choham Sudre‐Chinsky, Amirali Kalbasi, Daniela Harbich, Cornelia Flachskamm, Paula Fontanet, Sowmya Narayan, Manfred Uhr, Christian Namendorf, Camilla Bellone, Alon Chen, Felix Hausch, Juan Pablo Lopez, Mathias V. Schmidt   +15 more
wiley   +1 more source

Potential of Beauveria bassiana in the control of Euschistus crenator (Hemiptera: Pentatomidae) and selectivity to the parasitoid Telenomus podisi (Hymenoptera: Scelionidae). [PDF]

Pest Manag Sci
da Silva PHM, Carneiro GA, Polanczyk RA.
europepmc   +1 more source

Knowledge about Chagas disease among Primary Health Care professionals in a municipality located in northeastern Brazil. [PDF]

PLoS Negl Trop Dis
Almeida MC, Souza Soares JF, Santos RS, Ribeiro G, Reis RB, Bastos Araújo JM, Barbosa LM, Silva TO, Souza CN, Alves KKAF, Lanza FC, Guimarães do Nascimento PC, Carvalho Bastos CJ, Júnior RA, Britto Guimarães IC, Silva LK, de Freitas BS, Neto JLM, Reis MG.   +18 more
europepmc   +1 more source

Feasibility of a Green Breast Surgery Protocol to Reduce Carbon Footprint of Care: BuGS Trial Interim Results. [PDF]

J Clin Med
Vanni G, Materazzo M, Pellicciaro M, Caspi J, Di Mauro G, Tacconi F, Eskiu D, Longo B, Cervelli V, Berretta M, Buonomo OC, On Behalf Of BuGS Study Group.   +11 more
europepmc   +1 more source

Stink bug species composition and risk of economic damage in the southeastern soybean cropping systems. [PDF]

Environ Entomol
Panta S, Kennedy GG, Reisig DD, Vann RA, Aigner BL, Bekelja KM, Malone S, Doughty HB, Bryant TB, Kuhar TP, Huseth AS.   +10 more
europepmc   +1 more source