Results 1 to 10 of about 244,091 (217)
Building MLP networks by construction
We introduce two new models which are obtained through the modification of the well known methods MLP and cascade correlation. These two methods differ fundamentally as they employ learning techniques and produce network architectures that are not directly comparable.
M. HAGENBUCHNER +2 more
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Building Materials and Construction: Constructing a Quality of Life [PDF]
Catastrophes and new societal ambitions energized the huge construction effort undertaken between 1910 and 1970. The floods of 1917 and 1953 led to enormous investments in coastal defences. The government also undertook major investments in the construction of roadways and other infrastructural works.
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The ecological footprint of building construction [PDF]
This paper evaluates the environmental pressure that is generated by the construction of two types of building, through the application of ecological footprint analysis. The appraisal of the impact of human settlement on the environment is of great concern and environmentally-friendly buildings are actually required.
BASTIANONI, S. +3 more
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ABSTRACT Background 131I‐metaiodobenzylguanidine (131I‐MIBG) radiotherapy is a key treatment for relapsed and refractory (R/R) neuroblastoma (NB). Patients with R/R disease treated in the modern era are increasingly exposed to anti‐GD2 immunotherapy, which exerts selective pressure and may modify both tumor cell state and microenvironment.
Benjamin J. Lerman +7 more
wiley +1 more source
ABSTRACT Claudin‐6 has emerged as a promising immunotherapeutic target, yet protein‐level data in atypical teratoid/rhabdoid tumors (AT/RTs) have been inconsistent. We analyzed 36 well‐characterized AT/RT samples and found membranous claudin‐6 protein expression in 58% of cases, with striking enrichment in the molecular subgroup AT/RT‐TYR (100%) and ...
Victoria E. Fincke +4 more
wiley +1 more source
ABSTRACT Background Therapeutic apheresis (TA) is an established treatment modality for hematologic, neurologic, and immunologic disorders, yet access remains severely limited in sub‐Saharan Africa. Donor apheresis, including platelet apheresis collection from healthy donors, represents an important complementary modality supporting blood product ...
Nosa Bazuaye +33 more
wiley +1 more source
ABSTRACT Introduction Patients requiring long‐term continuous renal replacement therapy (CRRT) generally have poor prognoses. This study evaluated whether adding continuous intravenous sodium infusion (cIVNa) is associated with improved hemodynamics and outcomes in patients undergoing long‐term CRRT for ≥ 7 days.
Akinori Yamaguchi +6 more
wiley +1 more source
Enteropathogenic E. coli (EPEC) infects the human intestinal epithelium, resulting in severe illness and diarrhoea. In this study, we compared the infection of cancer‐derived cell lines with human organoid‐derived models of the small intestine. We observed a delayed in attachment, inflammation and cell death on primary cells, indicating that host ...
Mastura Neyazi +5 more
wiley +1 more source
Organoids in pediatric cancer research
Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley +1 more source
Building Materials and Construction: The Four Building Challenges
The chapter analyses the radical changes in the supply chain of building materials and construction between 1850 and 1910. It investigates the consequences for the four building challenges in this period: public hygiene, public housing, the struggle against water and the development of road infrastructure.
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