Results 151 to 160 of about 12,543,129 (302)
Circulating microRNAs as biomarkers of cachexia and sex‐specific cancer in senior dogs. In 25 client‐owned dogs, four circulating miRNAs (miR‐15a, miR‐15b, miR‐16, miR‐140) were downregulated in cachexia, with miR‐16 the strongest individual biomarker (AUC = 0.899).
Soon‐Seok Park +6 more
wiley +1 more source
Green Building Design in Public Building Design
openaire +1 more source
PANoptosis in the pathogenesis of myelodysplastic syndromes
PANoptosis, a combination of three types of programmed cell death, is mediated by a large protein complex called a PANoptosome. In healthy bone marrow hematopoietic cells, PANoptosis is restricted by inhibitory signaling. In MDS, bone marrow cells become sensitive to the PANoptotic stimuli due to the aberrant inactivation of inhibitory signaling or ...
Rohit Thalla +4 more
wiley +1 more source
Energy simulation in building design
Design decision support related to building energy consumption and / or indoor climate, should be based on an integral approach of environment, building, heating, ventilating and airconditioning (HVAC) system and occupants.
Hensen, J.L.M., Hensen, JLM Jan
core
Tumour heterogeneity and clonal evolution of metastatic salivary gland cancer were evaluated in two patients with adenoid carcinoma and one patient with myoepithelial carcinoma. Radiology‐guided autopsy enabled multi‐region sampling (total samples n = 149), followed by whole‐genome sequencing and phylogenetic reconstruction (17 tumour samples, 4–7 per ...
Gerben Lassche +10 more
wiley +1 more source
How AI Shapes the Future Landscape of Sustainable Building Design With Climate Change Challenges? [PDF]
Shen P +5 more
europepmc +1 more source
This study identifies somatostatin receptor 4 (Sstr4) as a critical tumor suppressor against skin and head/neck cancers (HNSCC, cSCC, and BCC). The loss of Sstr4 removes a check on cell growth, causing hyperactivation of the MAPK‐ERK signaling pathway (↑).
Ali Taqvi +6 more
wiley +1 more source
Multi-Scalar Design: Material Matters
Presented on January 15, 2019 from 12:00 p.m.-1:00 p.m. in the Caddell Building, Flex Space, Georgia Tech.Trained as an architect, Martin Bechthold is the Kumagai Professor of Architectural Technology at the Harvard Graduate School of Design, and ...
Bechthold, Martin
core +1 more source
Democratizing environmental impact assessment: An AI-augmented framework for sustainable building design. [PDF]
Nouri A, Hu M.
europepmc +1 more source
Partial inhibition of focal adhesion kinase (FAK) can paradoxically promote tumor growth, rather than simply producing a weaker antitumor effect than that observed with strong FAK suppression. In breast cancer and melanoma models, targeting p110δ PI3K, particularly in macrophages, counteracted these tumor‐promoting effects, highlighting the importance ...
Lydia Xenou +4 more
wiley +1 more source

