Results 121 to 130 of about 336,292 (314)

UiO‐66 metal–organic frameworks in biomedicine: From structural tunability to bioimaging, photodiagnostics, and photodynamic cancer therapy

open access: yesFEBS Open Bio, EarlyView.
UiO‐66(Zr) metal–organic frameworks are chemically stable, biocompatible, and highly tunable nanomaterials. Their modular structure enables controlled drug delivery, multimodal bioimaging, and light‐activated photodynamic therapy, supporting integrated diagnostic and therapeutic (theranostic) applications in cancer and biomedical research.
Veronika Huntošová   +2 more
wiley   +1 more source

Research on Predictive Analysis Method of Building Energy Consumption Based on TCN-BiGru-Attention

open access: yesApplied Sciences
Building energy consumption prediction has always played a significant role in assessing building energy efficiency, building commissioning, and detecting and diagnosing building system faults.
Sijia Fu, Rui Zhu, Feiyang Yu
doaj   +1 more source

Directed evolution of enzymes at the crossroads of tradition and innovation

open access: yesFEBS Open Bio, EarlyView.
An iterative cycle of data‐driven enzyme optimization comprising four stages: genetic diversification of a template enzyme, expression of protein variants, high‐throughput evaluation, and machine‐learning‐guided redesign of the next variant library.
Maria Tomkova   +2 more
wiley   +1 more source

Simulation model for assessing building energy-conservation policies [PDF]

open access: yes, 1980
A multiple-region simulation model for estimating economic, environmental, and energy-related impacts of building energy-conservation policies is presented.
Kleeman, P T
core  

A hybrid deep learning and clonal selection algorithm-based model for commercial building energy consumption prediction

open access: yesScience Progress
In contemporary society, commercial buildings, as a crucial component of urban development, face increasingly prominent energy consumption issues, posing significant challenges to the environment and sustainable development. Traditional energy management
Jichao Wang
doaj   +1 more source

Guiding AlphaFold to predict how Munc13‐1 opens Syntaxin‐1

open access: yesFEBS Open Bio, EarlyView.
The syntaxin‐1 Habc‐domain (orange), linker (pink) and SNARE motif (yellow) form a closed conformation that binds to Munc18‐1 (violet) and is opened by the Munc13‐1 MUN domain (cyan) to form the SNARE complex that triggers neurotransmitter release.
Madhurima Chattopadhyay   +2 more
wiley   +1 more source

Building Energy Modeling in Airport Architecture Design

open access: yes, 2018
Energy efficiency and Building Energy Modeling are two successful approaches to architecture, engineering, construction and operation (AECO) programs. In recent year several education initiatives focusing on buildings energy management have been carried out to provide professional profiles with specific skills in technology, architecture, engineering ...
Maria Antonietta Esposito   +1 more
openaire   +2 more sources

Molecular characterization of covRS mutations in M1UK Streptococcus pyogenes

open access: yesFEBS Open Bio, EarlyView.
Group A Streptococcus (GAS) acquires covRS mutations driving a hypervirulent bacterial state, frequently associated with invasive disease‐like necrotizing fasciitis. We demonstrate that the newly emerged M1UK GAS lineage can also acquire these mutations.
Jarrad Pritchard   +12 more
wiley   +1 more source

Agile, continuous building energy modeling and simulation

open access: yesSIMULATION
Digital twins have emerged as highly valuable tools for model-based planning, simulation and optimization over the last couple of years, thereby demonstrating considerable potential for application within the construction industry. The introduction of building information modeling (BIM) has effectively established a standardized approach to ...
Philipp Zech   +4 more
openaire   +1 more source

Aging Is a Key Driver for Adult Acute Myeloid Leukemia

open access: yesAging and Cancer, EarlyView.
Acute myeloid leukemia (AML) is a classical age‐related hematologic malignancy, and a key driver of AML is aging, which profoundly regulates intrinsic factors such as genomic instability, epigenetic reprogramming, and metabolic dysregulation, and alters bone marrow microenvironment.
Rong Yin, Haojian Zhang
wiley   +1 more source

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