Circulating microRNA profiles distinguish nonmalignant Lynch syndrome from cancer‐associated Lynch syndrome, sporadic colorectal cancer, and healthy controls. Age‐stratified analysis reveals disease‐specific regulatory states, and a six‐miRNA panel shows concordant separation in an independent colorectal tissue cohort.
Ramadhani Salum Chambuso +5 more
wiley +1 more source
Design Determinants of Building Envelope for Sustainable Built Environment: A Review
Building envelope separates indoor environment form outside environment as well as provides a comfortable indoor environment through an appropriate balance of passive and active technologies.
Gireendra Kumar, Gaurav Raheja
doaj +1 more source
Impact of building envelope design on Auckland public library energy consumption [PDF]
This study investigated impact of building envelope design on energy consumption of Auckland public libraries under local climatic conditions. Energy consumption data and library building envelope design data of the 30 libraries (55% of local library ...
Su, Bin
core
USP7 inhibits FOXO1 activity in chronic lymphocytic leukaemia cells enhancing cell survival
CLL cells rely on BCR‐mediated signalling for survival and proliferation in part through suppression of FOXO1. FOXO1 activity is regulated by a plethora of post‐translational modifications including phosphorylation and ubiquitination. We demonstrated that dual inhibition of BCR signalling and the deubiquitinase USP7 activates FOXO1, modulating its ...
Hassan N.B. Almuhanna +8 more
wiley +1 more source
Evaluation of the Performance of a Building Envelope Constructed with Phase-Change Materials in Relation to Orientation in Different Climatic Regions [PDF]
Minimizing the effect of climatic conditions and energy consumption in buildings are important issues to be considered in the building design process. Due to the changes in climatic conditions, there is an increase not only in the consumption of heating ...
Köse Eda, Manioğlu Gülten
doaj +1 more source
Evaluating the involvement of autolysosomes in the nuclear translocation of fluorescent proteins
Endogenously expressed fluorescent proteins can be degraded by autophagy and transported to cell nuclei via the nuclear pore complex. But in some cell lines, for example, HeLa cells which are positive for immunoreactivity of a receptor ligand, such as UCN I, in cell nuclei, fusion of autolysosome with the nuclear envelope is involved in the nuclear ...
Keiichi Ikeda
wiley +1 more source
Method of thermotechnical uniformity coefficient evaluation by analyzing thermograms [PDF]
One of the primary problems solved for increasing energy efficiency of a building is increasing of the insulating properties of the building envelope.
G.P. Vasilyev +3 more
doaj +1 more source
Loss of AMBRA1 activates MAPK and angiogenesis signaling pathways in melanoma cells
Loss of AMBRA1 in melanoma cells activates multiple oncogenic pathways associated with tumor progression. Transcriptomic and protein network analyses revealed that AMBRA1 depletion enhances MAPK/ERK signaling, angiogenesis, TGF‐β/EMT signaling, and Wnt/axon guidance pathways.
Milad Ibrahim +4 more
wiley +1 more source
Envelope Building materials play an important role in architecture by providing protection necessities, comfort, and technical performance while promoting an architectural language and an image.
Khaled Mansouri, Leila Sriti
doaj +1 more source
Construction Aspects of Hybrid Water-Filled Building Envelopes
Water-filled building envelopes are hybrid constructions with a solid and a fluid component, typically a glass or steel shell filled with water.
Matyas Gutai +5 more
doaj +1 more source

