Results 41 to 50 of about 3,325,526 (300)

Unique circulating miRNAome signatures captured with distinct molecular states in Lynch syndrome and sporadic colorectal cancer

open access: yesMolecular Oncology, EarlyView.
Circulating microRNA profiles distinguish nonmalignant Lynch syndrome from cancer‐associated Lynch syndrome, sporadic colorectal cancer, and healthy controls. Age‐stratified analysis reveals disease‐specific regulatory states, and a six‐miRNA panel shows concordant separation in an independent colorectal tissue cohort.
Ramadhani Salum Chambuso   +5 more
wiley   +1 more source

Design Determinants of Building Envelope for Sustainable Built Environment: A Review

open access: yesInternational Journal of Built Environment and Sustainability, 2016
Building envelope separates indoor environment form outside environment as well as provides a comfortable indoor environment through an appropriate balance of passive and active technologies.
Gireendra Kumar, Gaurav Raheja
doaj   +1 more source

Impact of building envelope design on Auckland public library energy consumption [PDF]

open access: yes, 2019
This study investigated impact of building envelope design on energy consumption of Auckland public libraries under local climatic conditions. Energy consumption data and library building envelope design data of the 30 libraries (55% of local library ...
Su, Bin
core  

USP7 inhibits FOXO1 activity in chronic lymphocytic leukaemia cells enhancing cell survival

open access: yesMolecular Oncology, EarlyView.
CLL cells rely on BCR‐mediated signalling for survival and proliferation in part through suppression of FOXO1. FOXO1 activity is regulated by a plethora of post‐translational modifications including phosphorylation and ubiquitination. We demonstrated that dual inhibition of BCR signalling and the deubiquitinase USP7 activates FOXO1, modulating its ...
Hassan N.B. Almuhanna   +8 more
wiley   +1 more source

Evaluation of the Performance of a Building Envelope Constructed with Phase-Change Materials in Relation to Orientation in Different Climatic Regions [PDF]

open access: yesE3S Web of Conferences, 2019
Minimizing the effect of climatic conditions and energy consumption in buildings are important issues to be considered in the building design process. Due to the changes in climatic conditions, there is an increase not only in the consumption of heating ...
Köse Eda, Manioğlu Gülten
doaj   +1 more source

Evaluating the involvement of autolysosomes in the nuclear translocation of fluorescent proteins

open access: yesFEBS Open Bio, EarlyView.
Endogenously expressed fluorescent proteins can be degraded by autophagy and transported to cell nuclei via the nuclear pore complex. But in some cell lines, for example, HeLa cells which are positive for immunoreactivity of a receptor ligand, such as UCN I, in cell nuclei, fusion of autolysosome with the nuclear envelope is involved in the nuclear ...
Keiichi Ikeda
wiley   +1 more source

Method of thermotechnical uniformity coefficient evaluation by analyzing thermograms [PDF]

open access: yesИнженерно-строительный журнал, 2016
One of the primary problems solved for increasing energy efficiency of a building is increasing of the insulating properties of the building envelope.
G.P. Vasilyev   +3 more
doaj   +1 more source

Loss of AMBRA1 activates MAPK and angiogenesis signaling pathways in melanoma cells

open access: yesFEBS Open Bio, EarlyView.
Loss of AMBRA1 in melanoma cells activates multiple oncogenic pathways associated with tumor progression. Transcriptomic and protein network analyses revealed that AMBRA1 depletion enhances MAPK/ERK signaling, angiogenesis, TGF‐β/EMT signaling, and Wnt/axon guidance pathways.
Milad Ibrahim   +4 more
wiley   +1 more source

The Effects of Envelope Building Materials on Thermal Comfort and Energy Consumption. Case of Hot and Dry Climate

open access: yesProceedings of the International Conference of Contemporary Affairs in Architecture and Urbanism-ICCAUA, 2019
Envelope Building materials play an important role in architecture by providing protection necessities, comfort, and technical performance while promoting an architectural language and an image.
Khaled Mansouri, Leila Sriti
doaj   +1 more source

Construction Aspects of Hybrid Water-Filled Building Envelopes

open access: yesJournal of Facade Design and Engineering, 2020
Water-filled building envelopes are hybrid constructions with a solid and a fluid component, typically a glass or steel shell filled with water.
Matyas Gutai   +5 more
doaj   +1 more source

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