Results 101 to 110 of about 245,559 (259)

DLiteNet: A Dual-Branch Lightweight Framework for Efficient and Precise Building Extraction from Visible and SAR Imagery

open access: yesRemote Sensing
High-precision and efficient building extraction by fusing visible and synthetic aperture radar (SAR) imagery is critical for applications such as smart cities, disaster response, and UAV navigation.
Zhe Zhao   +5 more
doaj   +1 more source

Finding novel vulnerabilities of hypomorphic BRCA1 alleles

open access: yesMolecular Oncology, EarlyView.
Synthetic lethality screens performed to identify novel vulnerabilities often model complete gene loss, thereby overlooking patient‐derived hypomorphic mutations. In this study, we have performed genome‐wide CRISPR screens on BRCA1 hypomorphic mutations, showing BRCA1I26A behaves like wild‐type, while BRCA1R1699Q mimics deficiency. Furthermore, we have
Anne Schreuder   +10 more
wiley   +1 more source

MSA-UNet: Multiscale Feature Aggregation with Attentive Skip Connections for Precise Building Extraction

open access: yesISPRS International Journal of Geo-Information
An accurate and reliable extraction of building structures from high-resolution (HR) remote sensing images is an important research topic in 3D cartography and smart city construction.
Guobiao Yao   +5 more
doaj   +1 more source

Effect of shadow in building detection and building boundary extraction

open access: yes, 2020
Yüksek çözünürlüklü hava/uydu görüntülerinden dikdörtgen yapılı binalarınbulunması iki farklı yöntem için önerilmektedir. Gölge bilgisi her iki algoritmadaana rolü üstlenmektedir. Algoritmalardan birisi Hough dönüşümü üzerine diğeri isemean shift algoritması üzerine kurulmuştur.
openaire   +1 more source

Longitudinal genome‐wide aneuploidy measurements in circulating cell‐free DNA to predict lack of benefit from pembrolizumab in patients with metastatic urothelial cancer

open access: yesMolecular Oncology, EarlyView.
Many patients with urothelial cancer do not benefit from treatment with pembrolizumab, while at risk of severe side effects. Changes in the levels of circulating tumor DNA early during treatment, measured by a simple and affordable assay that can be easily implemented in the clinic, can be used as a prognostic tool to identify these patients.
Youssra Salhi   +14 more
wiley   +1 more source

RPAFormer: Building Extraction with Relative Position Aggregated Transformer

open access: yesRemote Sensing
Automatic building extraction plays an important role in various remote sensing applications, such as seismic disaster investigation, seismic hazard risk assessment, urban planning, and photogrammetry.
Juehui Xing   +3 more
doaj   +1 more source

MITF maintains genome stability in nonmelanocyte lineages

open access: yesMolecular Oncology, EarlyView.
MITF is essential for melanocyte survival and acts as an oncogene in 10%–20% of melanomas. We show that MITF depletion causes genome instability in nonmelanocytic cells, leading to LATS2‐mediated P53 activation, cell cycle arrest, and apoptosis. This study highlights the role of MITF as a genome maintenance factor beyond the melanocyte lineage. Created
Drifa H. Gudmundsdottir   +13 more
wiley   +1 more source

Oncogenic DMTF1β promotes cancer cell motility by regulating autophagy through ULK1 stabilization

open access: yesMolecular Oncology, EarlyView.
In the current study, we demonstrate that the oncogene DMTF1β regulates ULK1 stability by reducing its proteasomal degradation in cancer cells. This stabilization enables ULK1 to induce autophagy, which in turn facilitates cancer cell migration. Consequently, reduced DMTF1β levels lead to decreased autophagy and impaired cancer cell migration.
Jun Xu   +13 more
wiley   +1 more source

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