Results 51 to 60 of about 245,559 (259)

Organoids in pediatric cancer research

open access: yesFEBS Letters, EarlyView.
Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley   +1 more source

Building Extraction Based on U-Net with an Attention Block and Multiple Losses

open access: yesRemote Sensing, 2020
Semantic segmentation of high-resolution remote sensing images plays an important role in applications for building extraction. However, the current algorithms have some semantic information extraction limitations, and these can lead to poor segmentation
Mingqiang Guo   +3 more
doaj   +1 more source

Making Low-Resolution Satellite Images Reborn: A Deep Learning Approach for Super-Resolution Building Extraction

open access: yesRemote Sensing, 2021
Existing methods for building extraction from remotely sensed images strongly rely on aerial or satellite-based images with very high resolution, which are usually limited by spatiotemporally accessibility and cost. In contrast, relatively low-resolution
Lixian Zhang   +5 more
doaj   +1 more source

Reciprocal control of viral infection and phosphoinositide dynamics

open access: yesFEBS Letters, EarlyView.
Phosphoinositides, although scarce, regulate key cellular processes, including membrane dynamics and signaling. Viruses exploit these lipids to support their entry, replication, assembly, and egress. The central role of phosphoinositides in infection highlights phosphoinositide metabolism as a promising antiviral target.
Marie Déborah Bancilhon, Bruno Mesmin
wiley   +1 more source

Super-Resolution-Based Snake Model—An Unsupervised Method for Large-Scale Building Extraction Using Airborne LiDAR Data and Optical Image

open access: yesRemote Sensing, 2020
Automatic extraction of buildings in urban and residential scenes has become a subject of growing interest in the domain of photogrammetry and remote sensing, particularly since the mid-1990s.
Thanh Huy Nguyen   +4 more
doaj   +1 more source

Spatiotemporal and quantitative analyses of phosphoinositides – fluorescent probe—and mass spectrometry‐based approaches

open access: yesFEBS Letters, EarlyView.
Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho   +3 more
wiley   +1 more source

GeoBoost: An Incremental Deep Learning Approach toward Global Mapping of Buildings from VHR Remote Sensing Images

open access: yesRemote Sensing, 2020
Modern convolutional neural networks (CNNs) are often trained on pre-set data sets with a fixed size. As for the large-scale applications of satellite images, for example, global or regional mappings, these images are collected incrementally by multiple ...
Naisen Yang, Hong Tang
doaj   +1 more source

The (Glg)ABCs of cyanobacteria: modelling of glycogen synthesis and functional divergence of glycogen synthases in Synechocystis sp. PCC 6803

open access: yesFEBS Letters, EarlyView.
We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee   +3 more
wiley   +1 more source

SDSNet: Building Extraction in High-Resolution Remote Sensing Images Using a Deep Convolutional Network with Cross-Layer Feature Information Interaction Filtering

open access: yesRemote Sensing, 2023
Building extraction refers to the automatic identification and separation of buildings from the background in remote sensing images. It plays a significant role in urban planning, land management, and disaster monitoring. Deep-learning methods have shown
Xudong Wang   +6 more
doaj   +1 more source

Calpain small subunit homodimerization is robust and calcium‐independent

open access: yesFEBS Letters, EarlyView.
Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy   +4 more
wiley   +1 more source

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