Results 51 to 60 of about 267,276 (259)

Organoids in pediatric cancer research

open access: yesFEBS Letters, EarlyView.
Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley   +1 more source

Super-Resolution-Based Snake Model—An Unsupervised Method for Large-Scale Building Extraction Using Airborne LiDAR Data and Optical Image

open access: yesRemote Sensing, 2020
Automatic extraction of buildings in urban and residential scenes has become a subject of growing interest in the domain of photogrammetry and remote sensing, particularly since the mid-1990s.
Thanh Huy Nguyen   +4 more
doaj   +1 more source

Diversity and complexity in neural organoids

open access: yesFEBS Letters, EarlyView.
Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley   +1 more source

GeoBoost: An Incremental Deep Learning Approach toward Global Mapping of Buildings from VHR Remote Sensing Images

open access: yesRemote Sensing, 2020
Modern convolutional neural networks (CNNs) are often trained on pre-set data sets with a fixed size. As for the large-scale applications of satellite images, for example, global or regional mappings, these images are collected incrementally by multiple ...
Naisen Yang, Hong Tang
doaj   +1 more source

Residual tail twisting in ascidian larvae is stabilized by asymmetric myofibrils that resist bilateral symmetry restoration

open access: yesFEBS Letters, EarlyView.
Ascidian Ciona larvae initially show strong clockwise tail twisting, which is largely corrected during development. However, a small residual twist remains. This study shows that organized helical myofibrils in tail muscles mechanically stabilize this residual asymmetry, preventing complete restoration of bilateral symmetry and revealing how embryos ...
Yuki S. Kogure   +3 more
wiley   +1 more source

A Building Extraction Approach Based on the Fusion of LiDAR Point Cloud and Elevation Map Texture Features

open access: yesRemote Sensing, 2019
Building extraction is an important way to obtain information in urban planning, land management, and other fields. As remote sensing has various advantages such as large coverage and real-time capability, it becomes an essential approach for building ...
Xudong Lai   +3 more
doaj   +1 more source

Making Low-Resolution Satellite Images Reborn: A Deep Learning Approach for Super-Resolution Building Extraction

open access: yesRemote Sensing, 2021
Existing methods for building extraction from remotely sensed images strongly rely on aerial or satellite-based images with very high resolution, which are usually limited by spatiotemporally accessibility and cost. In contrast, relatively low-resolution
Lixian Zhang   +5 more
doaj   +1 more source

The human gut microbiome across the life course

open access: yesFEBS Letters, EarlyView.
Despite significant individual variation and continuous change throughout life, the human gut microbiome follows some life stage‐specific trends. This article provides a brief overview of how gut microbiome composition shifts across different phases of life. Created in BioRender. Özkurt, E. (2026) https://BioRender.com/8q4nrnc.
Alise J. Ponsero   +4 more
wiley   +1 more source

Degradation mechanism of the von Willebrand factor A2 domain by nattokinase

open access: yesFEBS Letters, EarlyView.
Nattokinase, a natto‐derived protease, exhibits potent antithrombotic effects. This study demonstrates that nattokinase directly cleaves the von Willebrand factor (vWF) A2 domain in vitro. Unlike the native regulator ADAMTS13, nattokinase degrades folded vWF independently of shear stress.
Ryuichi Hyakumoto   +3 more
wiley   +1 more source

From mice to humans—divergent strategies for intestinal homeostasis and regeneration

open access: yesFEBS Letters, EarlyView.
Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa   +2 more
wiley   +1 more source

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