Results 151 to 160 of about 7,736,972 (396)

Developing evidence‐based, cost‐effective P4 cancer medicine for driving innovation in prevention, therapeutics, patient care and reducing healthcare inequalities

Molecular Oncology, EarlyView.
The cancer problem is increasing globally with projections up to the year 2050 showing unfavourable outcomes in terms of incidence and cancer‐related deaths. The main challenges are prevention, improved therapeutics resulting in increased cure rates and enhanced health‐related quality of life.
Ulrik Ringborg, Joachim von Braun, Julio Celis, Anton Berns, Michael Baumann, Tit Albreht, Nancy Abou‐Zeid, Vanderlei Bagnato, Christian Brandts, Chien‐Jen Chen, Massimiliano di Pietro, Manjit Dosanjh, Thomas Dubois, Alexander Eggermont, Angelika Eggert, Ingemar Ernberg, Sara Faithfull, Johannes Förner, Stefan Fröhling, Manuel Heitor, Leroy Hood, Wei Jiang, Bengt Jönsson, Ravi Kannan, Maria Leptin, Su Li, Peter Lindgren, Douglas Lowy, Jun Ma, Alex Markham, Péter Nagy, Simon Oberst, M. Iqbal Parker, Danielle Rodin, Kevin Ryan, Joachim Schüz, Richard Sullivan, Josep Tabernero, Peter Turkson, Oliver Várhelyi, Harold Varmus, Chijie Wang, Elisabete Weiderpass, Nils Wilking   +43 more
wiley   +1 more source

A study of BIM collaboration requirements and available features in existing model collaboration systems [PDF]

, 2013
Established collaboration practices in the construction industry are document centric and are challenged by the introduction of Building Information Modelling (BIM). Document management collaboration systems (e.g.
Lockley, Steve, Matthews, Jane, Shafiq, Muhammad Tariq   +2 more
core  

A Systematic Review of the Digital Transformation of the Building Construction Industry

IEEE Access
Construction sector spending makes a significant contribution to the global economy, with approximately ${\$}$ 10 trillion being spent on building and construction activities annually.
Khalid K. Naji, Murat Gunduz, Fahid Alhenzab, Hamed Al-Hababi, Abdulla Al-Qahtani   +4 more
semanticscholar   +1 more source

Cell surface interactome analysis identifies TSPAN4 as a negative regulator of PD‐L1 in melanoma

Molecular Oncology, EarlyView.
Using cell surface proximity biotinylation, we identified tetraspanin TSPAN4 within the PD‐L1 interactome of melanoma cells. TSPAN4 negatively regulates PD‐L1 expression and lateral mobility by limiting its interaction with CMTM6 and promoting PD‐L1 degradation.
Guus A. Franken, Andrea Abel Gutierrez, Imke van Rossum, Cornelia G. Spruijt, Michiel Vermeulen, Guido van Mierlo, Blanca Scheijen, Annemiek B. van Spriel   +7 more
wiley   +1 more source

Solar energy use for energy savings in dairy processing plants [PDF]

, 2007
New Zealand is one of the world’s largest producers of dairy products and has a climate with high levels of solar radiation; however, the use of solar energy in the dairy processing industry has received limited attention.
Anderson, Timothy Nicholas, Duke, Mike
core  

Building Information Modelling: Challenges and Barriers in Implement of BIM for Interior Design Industry in Malaysia [PDF]

, 2018
A B Abd Hamid, Mohd Zafrullah Mohd Taib, A H N Abdul Razak, Mohamed Rashid Embi   +3 more
openalex   +1 more source

Plecstatin inhibits hepatocellular carcinoma tumorigenesis and invasion through cytolinker plectin

Molecular Oncology, EarlyView.
The ruthenium‐based metallodrug plecstatin exerts its anticancer effect in hepatocellular carcinoma (HCC) primarily through selective targeting of plectin. By disrupting plectin‐mediated cytoskeletal organization, plecstatin inhibits anchorage‐dependent growth, cell polarization, and tumor cell dissemination.
Zuzana Outla, Jan Kosla, Magdalena Prechova, Lukas Frick, Patricia Bortel, Yasmin Borutzki, Andrea Bileck, Christopher Gerner, Samuel M. Meier‐Menches, Selma Osmanagic‐Myers, Martin Gregor   +10 more
wiley   +1 more source

Large industrial building

, 2023
This is the final report of an EPS project about large industrial building. During a year abroad at Escola Politècnica Superior d'Enginyeria de Vilanova i la Geltrú, the team was faced with the real life problem of a Spanish company offering two services.
Salihu, Lorik, Jarkiewicz, Carola, Rolfes, Gino, Dressel, Pascal   +3 more
openaire   +1 more source

Recurrent cancer‐associated ERBB4 mutations are transforming and confer resistance to targeted therapies

Molecular Oncology, EarlyView.
We show that the majority of the 18 analyzed recurrent cancer‐associated ERBB4 mutations are transforming. The most potent mutations are activating, co‐operate with other ERBB receptors, and are sensitive to pan‐ERBB inhibitors. Activating ERBB4 mutations also promote therapy resistance in EGFR‐mutant lung cancer.
Veera K. Ojala, Sini Ahonen, Sara Peltola, Aura Tuohisto‐Kokko, Olaya Esparta, Peppi Suominen, Anne Jokilammi, Iman Farahani, Deepankar Chakroborty, Nikol Dibus, Steffen Boettcher, Tomi T. Airenne, Mark S. Johnson, Lisa D. Eli, Klaus Elenius, Kari J. Kurppa   +15 more
wiley   +1 more source

A Novel Approach for Predicting CO₂ Emissions in the Building Industry Using a Hybrid Multi-Strategy Improved Particle Swarm Optimization–Long Short-Term Memory Model

Energies
The accurate prediction of carbon dioxide (CO2) emissions in the building industry can provide data support and theoretical insights for sustainable development.
Yuyi Hu, Bojun Wang, Yanping Yang, Liwei Yang   +3 more
doaj   +1 more source