Results 61 to 70 of about 140,147 (244)
Advanced Science, EarlyView.This non‑enzymatic function of DHODH drives sunitinib resistance by competing with TRIM37 to block TRIM28 ubiquitination, thereby stabilizing TRIM28 and activating VEGFA transcription. Disrupting the DHODH–TRIM28 interaction with lisaftoclax restores drug sensitivity.
Shijie Qian +10 more
wiley +1 more source
Journal of Civil Engineering and Management, 2021 The emerging Building Information Modeling (BIM) can better promote the development of building industrialization, with data integration between information-rich building models and business processes.
Ping Wu +5 more
doaj +1 more source
, 2021 Construction is a complex industry. A system like Building Information Modeling (BIM) has benefited many construction players in order to expedite their works effectively and efficiently in terms of design, implementation, and management of a project. As
Z. Sriyolja, N. Harwin, K. Yahya
semanticscholar +1 more source
Cancer‐Associated BCL‐2 Mutants Reveal Mechanisms Towards Venetoclax Resistance
Advanced Science, EarlyView.Venetoclax (VEN) resistance in chronic lymphocytic leukemia arises from diverse BCL2 mutations. We map mechanisms contributing to VEN resistance across common BCL‐2 variants. G101V and D103Y reduce drug binding and increase sequestration of pro‐apoptotic proteins. V156D blocks VEN allosterically.
Jonas Aufdermauer +9 more
wiley +1 more source
IEEE Access, 2020 Computer Aided Design (CAD) systems play an important role in the production of building designs that are used to assist building constructions. Thus, CAD building drawings contain a large amount of building data important for indoor navigation and other
Chi Zhang +4 more
doaj +1 more source
Surface and Interfacial Engineering toward Durable Mechanically Coupled Flexible Electronics
Advanced Science, EarlyView.This Review highlights how surface and interfacial engineering governs the reliability, durability, and functional stability of mechanically coupled flexible electronics. By integrating fundamental interfacial theory, failure mechanisms, multiscale engineering strategies, and representative applications, it provides a design‐oriented framework for ...
Qian Wang, Fangfang Dai, Wei Wu
wiley +1 more source
Thermal Performance Visualization Using Object−Oriented Physical and Building Information Modeling
Applied Sciences, 2020 This study demonstrates the research and development of a visualization method called thermal performance simulation. The objective of this study is providing the results of thermal performance simulation results into building information modeling (BIM ...
WoonSeong Jeong, Wei Yan, Chang Joon Lee
doaj +1 more source
Advances in Civil Engineering, 2018 Rigorous research and practical experience have allowed building information modeling (BIM) to be successfully adopted in the traditional design process without being severely cumbersome.
Yongwook Jeong
doaj +1 more source
Kajian Implementasi Building Information Modeling (BIM) di Dunia Konstruksi Indonesia
Rekayasa Sipil, 2021 One of the most common obstacles encountered in the construction industry is the fragmented delivery process and relies on paper-based documentation and communication. To overcome these problems a good integration system is needed.
Januar Pantiga, Anton Soekiman
semanticscholar +1 more source
A method for transferring BIM data into domain ontologies: A case study based on airport services
Egyptian Informatics Journal, 2022 Building Information Modeling (BIM) has revolutionized the construction industry as a platform for core integrated design, modeling, asset planning, and collaboration. Although BIM simplifies the retrieval and use of information in construction projects,
J.J. Herrera-Martín +3 more
doaj +1 more source