Results 161 to 170 of about 100,537 (296)

Building Information Modelling and Intellectual Propertization: A Revolutionary Nirvana or a Disillusionment?

open access: yes, 2014
Building information modelling (BIM) epitomizes the capacity of a construction project team to deliver satisfactory project outcomes through process integration and multi-disciplinary collaboration by using virtual modeling platforms.
Olatunji, Oluwole
core  

Identifying gene expression signatures for risk stratification of postoperative adjuvant chemotherapy in colorectal cancer

open access: yesFEBS Open Bio, EarlyView.
A novel signature integrating genome‐wide analysis with clinical factors predicts recurrence in stage II colorectal cancer and enables a new risk stratification to guide postoperative adjuvant chemotherapy. Clinical risk stratification for postoperative recurrence in patients with pathological stage II (pStage II) colorectal cancer (CRC) is essential ...
Mayuko Otomo   +7 more
wiley   +1 more source

Analysis Framework for the Interaction Between Lean Construction and Building Information Modelling

open access: yes
Building with Building Information Modelling (BIM) changes design and production processes. But can BIM be used to support process changes designed according to lean production and lean construction principles? To begin to answer this question we provide
Owen, Robert   +3 more
core  

Modelling information flow for organisations delivering microsystems technology [PDF]

open access: yes, 2011
Motivated by recent growth and applications of microsystems technology (MST), companies within the MST domain are beginning to explore avenues for understanding, maintaining and improving information flow, within their organisations and to/from customers,
Durugbo, Christopher
core  

YIPFα1A expression is regulated by multilayered molecular mechanisms

open access: yesFEBS Open Bio, EarlyView.
YIPFα1A, a five‐pass Golgi protein, is regulated at multiple layers. (1) Rare‐codon enrichment drives translation‐coupled mRNA decay. (2) A proximal 3′‐UTR element stabilizes mRNA. (3) A distal 3′‐UTR element included by alternate poly(A) site usage represses translation, which can be overridden by the proximal 3′‐UTR element.
Tokio Takaji   +2 more
wiley   +1 more source

Derivation and characterization of retinal pigment epithelium from urine‐derived iPSCs

open access: yesFEBS Open Bio, EarlyView.
Age‐related macular degeneration causes vision loss via RPE dysfunction and loss. Traditional iPSC therapies rely on invasive biopsies, limiting scalability. Here, we utilize urine‐derived stem cells as an accessible source to generate u‐iPSCs, successfully differentiated into pigmented RPE. This “Urine‐to‐Retina” platform provides a promising path for
Daniella Beiner   +7 more
wiley   +1 more source

Molecular dynamics simulations of positively selected codons in FcγRI reveal novel biochemical binding properties

open access: yesFEBS Open Bio, EarlyView.
Evolutionary analysis across 32 placental mammals identified positive selection at residues H148 and W149 in the immune receptor FcγR1. Ancestral reconstruction combined with molecular dynamics simulations reveals how these mutations may influence receptor structure and dynamics, providing insight into the evolution of antibody recognition and immune ...
David A. Young   +7 more
wiley   +1 more source

Delivering building simulation information via new communication media

open access: yes, 2007
Often, the goal of understanding how the building works and the impact of design decisions is hampered by limitations in the presentation of performance data.
Clarke, Joseph Andrew   +3 more
core   +1 more source

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