Results 41 to 50 of about 19,174,203 (199)

Selective Modulation of OTUB1 Noncanonical Function via a bioPhosTAC Strategy

open access: yesAdvanced Science, EarlyView.
This work positions the versatile performance of the peptide‐based bioPhosTAC platform for dissecting phosphorylation‐dependent biology and expanding the scope of induced‐proximity technologies. We demonstrated that selective manipulation of a tyrosine phosphorylation site is sufficient to propagate coordinated cellular consequences.
Seung Un Seo   +7 more
wiley   +1 more source

A Scan-to-BIM Methodology Applied to Stone Pavements in Archaeological Sites

open access: yesHeritage, 2021
The transition from Building Information Modelling (BIM) to Heritage Building Information Modelling (H-BIM) is intended to pursue an adequate knowledge of the artefact that is to be preserved, progressively replacing the traditional methods of ...
Mattia Intignano   +7 more
doaj   +1 more source

Understanding and Regulating C–N Coupling Pathways for Electrocatalytic Urea Synthesis From CO2 and NO3−/NO2−

open access: yesAdvanced Science, EarlyView.
Understanding and regulating C–N coupling is central to electrocatalytic urea synthesis from CO2 and NO3−/NO2−. This review outlines representative coupling pathways, summarizes carbon‐ and nitrogen‐side intermediate regulation strategies, and highlights in situ/operando tools for mechanistic clarification and catalyst design. ABSTRACT Electrocatalytic
Xingbao Chen   +5 more
wiley   +1 more source

Lean construction, building information modelling and sustainability [PDF]

open access: yes
This paper investigates the mutual relations of three current drivers of construction: lean construction, building information modelling and sustainability.
Owen, Bob, Koskela, Lauri, Dave, Bhargav
core   +3 more sources

From BIM to BEM—Modern Thermal Simulations Using a Building Information Management Model: A Case Study

open access: yesApplied Sciences
This article raises awareness of Building Information Management (BIM) and its significance for Construction 4.0. BIM is often mistakenly understood only as a 3D model of a building object, but its true potential lies in the information associated with ...
David Průša   +6 more
doaj   +1 more source

SPRED2 Negatively Regulates CD8+ T Cell‐Mediated Antitumor Immunity in Breast Cancer

open access: yesAdvanced Science, EarlyView.
Sprouty‑related EVH1 domain containing 2 (SPRED2) restrains Ras/Raf/ERK signaling in CD8+ T cells. Host SPRED2 deficiency enhances T‐cell survival, cytotoxicity, and memory‐like phenotypes, reducing primary tumor growth and endpoint lung metastatic burden in breast cancer models.
Miao Tian   +8 more
wiley   +1 more source

Structural Analysis Ready Building Information Modelling: A Requirement Analysis [PDF]

open access: yesThe International Archives of the Photogrammetry, Remote Sensing and Spatial Information Sciences
Structural analysis is utilised to evaluate the behaviour of structures under applied loads to ensure their safety and stability. It is crucial in designing, assessing, and retrofitting buildings and structures.
M. Akhoundi Khezrabad   +2 more
doaj   +1 more source

Directions for the formation of «City Intelligent models» using artificial intelligence for the post-war reconstruction of historical buildings

open access: yesBudownictwo i Architektura
Addressing the limitations of current digital simulations for historical buildings, this paper suggests a specific technical task for the development of a simulation analysis platform based on City Intelligent Modelling (CIM).
Dmytro Chashyn   +2 more
doaj   +1 more source

Optimizing Energy Efficiency in Operating Built Environment Assets through Building Information Modeling: A Case Study

open access: yesEnergies, 2017
Reducing carbon emissions and addressing environmental policies in the construction domain has been intensively explored with solutions ranging from energy efficiency techniques with building informatics to user behavior modelling and monitoring.
Ioan Petri   +4 more
doaj   +1 more source

Building Information Modelling and Energy Simulation for Architecture Design

open access: yesApplied Sciences, 2021
Over the years, building information modelling (BIM) has undergone a significant increase, both in terms of functions and use. This tool can almost completely manage the entire process of design, construction, and management of a building internally ...
Marina Bonomolo   +2 more
doaj   +1 more source

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