Results 101 to 110 of about 483,067 (315)
Molecular Oncology, EarlyView.Drug resistance limits treatment success in a subset of lung cancers driven by ROS1 gene alterations. Using patient‐derived cells and computer simulations, we studied three key mutations and how they affect five targeted drugs. The mutations reduced drug effectiveness in different ways by altering protein structure and behavior.
Farhan Ul Haq +8 more
wiley +1 more source
Building technology and its use
, 1978 Technology transfer, the diffusion of new or existing technical knowledge into and throughout the building industry, is discussed with reference to the Canadian industry and the activities of the Division of Building Research of the National Research ...
Crawford, C. B.
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US-India Technology Co-operation and Capability Building: The Role of Inter-firm Alliances in Knowledge Based Industries [PDF]
The paper reviews some Indo-US technology cooperation initiatives and analyses data on inter-firm alliances in knowledge based industries, especially Information Technology (IT).
Basant, Rakesh
core +2 more sources
Raman‐based label‐free microscopic analysis of the pancreas in living zebrafish larvae
FEBS Open Bio, EarlyView.Forward stimulated Raman scattering (F‐SRS) and epi coherent anti‐Stokes Raman scattering (E‐CARS) allow label‐free discrimination of distinct subcellular structures in the pancreas of living zebrafish larvae. Given the straightforward applicability, we anticipate broad implementation of Raman microscopy in other organs and across various biomedical ...
Noura Faraj +3 more
wiley +1 more source
Publications on Canadian building technology
, 1978 This Digest is intended to serve as a short introduction to the main Canadian sources of printed information on building technology. The places to begin a search for published information or for directories and periodicals are libraries, either public ...
Williams, G. P., Carson, E. R.
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FEBS Open Bio, EarlyView.CRISPRI‐mediated gene silencing and phenotypic exploration in nontuberculous mycobacteria. In this Research Protocol, we describe approaches to control, monitor, and quantitatively assess CRISPRI‐mediated gene silencing in M. smegmatis and M. abscessus model organisms.
Vanessa Point +7 more
wiley +1 more source
, 2015 none - englishThe present special issue of the Journal Information Technology in Construction entails a selection of papers initially presented at the 10th ECPPM (European Conference on Product and Process Modelling) conference, held September 2014 and ...
core
FEBS Open Bio, EarlyView.Enzymes of the 2‐hydroxyacyl‐CoA lyase group catalyze the condensation of formyl‐CoA with aldehydes or ketones. Thus, by structural adaptation of active sites, practically any pharmaceutically and industrially important 2‐hydroxyacid could be biotechnologically synthesized. Combining crystal structure analysis, active site mutations and kinetic assays,
Michael Zahn +4 more
wiley +1 more source
Stochastic information technology modelling for business processes
, 2002 This thesis was submitted for the degree of Doctor of Philosophy and awarded by Brunel University.Business Processes (BP) and Information Technology (IT) are two areas that work very closely in helping organisations to keep or retain competitive ...
Serrano, Alan Edwin
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FEBS Open Bio, EarlyView.Time‐resolved X‐ray solution scattering captures how proteins change shape in real time under near‐native conditions. This article presents a practical workflow for light‐triggered TR‐XSS experiments, from data collection to structural refinement. Using a calcium‐transporting membrane protein as an example, the approach can be broadly applied to study ...
Fatemeh Sabzian‐Molaei +3 more
wiley +1 more source