Results 101 to 110 of about 4,215,244 (301)

Structures of mycobacterial 3‐methylcrotonyl‐CoA carboxylase reveal carrier‐domain translocation between catalytic sites

FEBS Letters, EarlyView.
Mycobacterial 3‐methylcrotonyl‐CoA carboxylase uses a mobile biotin‐carrying domain to shuttle a carboxyl group between two catalytic sites, enabling carboxylation of 3‐methylcrotonyl‐CoA during leucine breakdown. Cryo‐electron microscopy captures the carrier at both sites and reveals an inward loop movement that may prevent futile rebinding to the ...
Ajit Yadav, Bogdan I. Florea, Sebastian Geibel   +2 more
wiley   +1 more source

Building Maintenance Management

, 2021
Buildings are some of the most valuable assets of any nation, in the sense that they provide people shelter, places to work and leisure, and so many others functions. With the rising costs of new buildings, the need for Building Maintenance (BM), has become even more relevant, since it allows the qualification of the built portfolio, helps boosting the
openaire   +1 more source

From junk to function — How weak selection in eukaryotes builds new parts and drives genomic complexity

FEBS Letters, EarlyView.
How do genomes gain new functional parts? In eukaryotes, which tend to evolve under weak selection, much of the genome is junk. Palazzo and Qiu borrow the logic of Markov chains to show how non‐functional DNA becomes functional through the appearance of intermediate states, which arise due to epistasis, buffering, and biochemical messiness, allowing ...
Alexander F. Palazzo, Yi Qiu
wiley   +1 more source

Enhancing Cost Prediction and Estimation Techniques for Sustainable Building Maintenance and Future Development

Encyclopedia
Building maintenance is crucial, yet predicting financial resources for it remains challenging, particularly during the design and construction phases. This research aims to analyze and synthesize existing studies on maintenance cost estimation, with a ...
Dino Obradović, Hana Begić Juričić, Hrvoje Krstić   +2 more
doaj   +1 more source

L‐aspartate oxidase provides new insights into fumarate reduction in anaerobic darkness in Synechocystis sp. PCC6803

FEBS Letters, EarlyView.
Synechocystis strains deficient in succinate dehydrogenase (SDH) secrete more succinate than the WT under dark anaerobic conditions, supporting that SDH then primarily acts as SDH, not as a fumarate reductase. L‐aspartate oxidase (Laspo) from Synechocystis is functional under anaerobic conditions, reducing fumarate to succinate.
Kateryna Kukil, Jeffrey A. Hawkes, Cecilia Blikstad, Pia Lindberg   +3 more
wiley   +1 more source

Synthesis of Multi-Criteria Decision-Making Applications in Facilities Management and Building Maintenance: Trends, Methods, and Future Research Directions

Buildings
Building maintenance decisions are complex and often influenced by various factors. Multi-criteria decision-making (MCDM) methods have been widely applied to address this complexity, yet guidance on selecting the most appropriate method for specific ...
Mahdi Anbari Moghadam, Deniz Besiktepe
doaj   +1 more source

Artificial molecular machines and motors—Design and control of nanoscale motion

FEBS Letters, EarlyView.
Molecules are constantly moving because of thermal fluctuations, but random motion alone cannot be exploited to perform directional tasks. Artificial molecular machines use chemical, electrical, or light energy to bias this motion. Molecular shuttles, rotary motors, and supramolecular pumps illustrate how nanoscale movement can be controlled and ...
Leonardo Andreoni, Alberto Credi
wiley   +1 more source

The efficiency and effectiveness of building maintenance for College Tun Hussein Onn (KTHO), Universiti Teknologi Malaysia [PDF]

, 2010
Buildings are the most valuable assets in a nation, which providing people with shelter and facilities for work and leisure. A correspondingly strong building conservation movement has also directed attention towards the older built stock such as the ...
Wong, Chin Liang
core  

Maintenance Building: Frame construction

, 2020
The black and white photographs document the early development of the ...
Commonwealth News and Information Bureau, Photographer: not known   +1 more
core   +1 more source

Advantages of using insulation with lower thermal conductivity versus WT 2021 – comparison of the costs of materials, buying and operating a heating device, and a carbon footprint generated

Budownictwo i Architektura
This article presents a comparative analysis of the use of standard insulation material compliant with the current Technical Conditions WT 2021, compared to insulation material with improved thermal conductivity parameters on building partitions.
Patrycja Zawiska
doaj   +1 more source