Results 71 to 80 of about 4,215,244 (301)

Modelling stem cell differentiation related processes—A practical overview for biologists

open access: yesFEBS Letters, EarlyView.
Stem cell differentiation is complex and difficult to control experimentally. This review introduces suitable computational modelling approaches that can support stem cell research, from mechanistic ODE and abstract models to multiscale and deep learning methods.
Ricco Zeegelaar   +4 more
wiley   +1 more source

Building appraisal, maintenance and preservation

open access: yes, 1985
Incl. Technology and Conservation 1978 (4/78) 8 ppSIGLEAvailable from British Library Document Supply Centre- DSC:86/14497(Building) / BLDSC - British Library Document Supply CentreGBUnited ...
Bath Univ. (United Kingdom). Dept. of Architecture and Building Engineering   +2 more
core  

Maintenance Building

open access: yes, 2020
The black and white photographs document the early development of the ...
Commonwealth News and Information Bureau   +1 more
core   +1 more source

Reconstructing enzyme evolution by protein engineering

open access: yesFEBS Letters, EarlyView.
Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler   +2 more
wiley   +1 more source

A Methodological Approach to Assessing Constructability in Building Maintenance and Its Impact on University Quality

open access: yesBuildings
This study introduces and evaluates an innovative methodology for assessing constructability in the maintenance of university buildings, aiming to improve the quality of academic infrastructure.
Mónica Escate, Doris Esenarro
doaj   +1 more source

Investigating transcription factor dynamics in health and disease using FRAP

open access: yesFEBS Letters, EarlyView.
FRAP analysis of GFP‐tagged transcription factors reveals how molecular mobility and target engagement change in response to drug treatment. By combining live‐cell imaging, quantitative model fitting, and statistical analysis, this approach uncovers transcription factor dynamics linked to disease mechanisms, providing a powerful framework for ...
Kannan Govindaraj   +3 more
wiley   +1 more source

Some basilar questions about building maintenance

open access: yes, 1994
The paper presents some considerations on the usage of several maintenance strategies in relation to building typologies with particular reference to "simple" buildings used as dwellings, and "complex" buildings of the services sector.
CECCHINI, Cecilia
core  

Assessment of the Effects of Deferred Maintenance on the Current Technical Condition of a Building: Case Study—A Former Fire Station in Nowy Raduszec

open access: yesApplied Sciences
The degradation of building elements progresses with the age of a building as a result of natural ageing processes. The lack of regular maintenance, repair, and renovation works during the operational phase accelerates degradation processes, leading to ...
Aleksandra Kurowska-Rajchel   +1 more
doaj   +1 more source

Conserved binding mode but diverse interfaces of MreC‐PBP2 interactions

open access: yesFEBS Letters, EarlyView.
The crystal structure of abMreC reveals a conserved two β‐barrel architecture and provides structural insights into its role within the bacterial elongasome. The abMreC–abPBP2 complex model identifies the molecular basis of MreC‐mediated PBP2 recognition, contributing to the regulation of peptidoglycan synthesis.
Hyunseok Jang   +4 more
wiley   +1 more source

Strategies of Public University Building Maintenance—A Literature Survey

open access: yes
In this article, comprehensive insights into the field of building maintenance, emphasizing the importance of keywords, collaborative efforts among authors, and the evolving research landscape, are provided.
Edyta Plebankiewicz, Jakub Grącki
core   +1 more source

Home - About - Disclaimer - Privacy