Results 171 to 180 of about 222,681 (219)

A New Model for Youth-Driven Community Change: Exploratory Testing of Artificial Intelligence-Supported Citizen Science. [PDF]

JMIR AI
De la Vega-Taboada E, Portillo SA, Gomez-Garcia LM, Banchoff A, Bermudez VM, Chavez DM, Sgaraglino TI, Flores Millender E, Sarmiento OL, King AC.   +9 more
europepmc   +1 more source

Dual native G‐quadruplex folding is associated with chromatin looping at the MYC locus

FEBS Open Bio, EarlyView.
BG4‐detectable G‐quadruplex (G4) in HaCaT and NHEK keratinocytes identified folded and unfolded G4s enriched at promoters/TSSs and active enhancers, whereas unfolded G4s also overlapped weak/poised enhancers. At MYC–PVT1, 3C‐qPCR detected enhancer–promoter looping only when G4s were simultaneously folded at both regulatory elements under native ...
Dieila Giomo de Lima, Gustavo Narvaes Guimarães, Emilyane de Oliveira Santana Amaral, Bianca Caroline Figueiredo Bianco, Manuel Jara‐Espejo, Sérgio Roberto Peres Line, Ana Paula de Souza, Aline Cristiane Planello   +7 more
wiley   +1 more source

The use of implementation science frameworks to promote maternal and child health delivery programs in Nigeria. [PDF]

Front Health Serv
Onuorah UM, Nwuzoh MI, Onukansi FO, Anokwuru CC, Ikhuoria OV, Obi CG, Eneh SC.   +6 more
europepmc   +1 more source

Avidin is evolutionarily conserved in fish but dispensable for development and resistance against Streptococcus agalactiae in zebrafish

FEBS Open Bio, EarlyView.
The presence of biotin‐binding avidin proteins in fish and their biological significance are poorly characterized. We cataloged fish avidins and demonstrate that they are widely present and evolutionarily conserved. We created avd knockout zebrafish and show that zebavidin is dispensable for development and that resistance of avd knockout embryos in ...
Anni K. Saralahti, Markus J. T. Ojanen, Mataleena Parikka, Otto Kauko, Mika Rämet, Vesa P. Hytönen   +5 more
wiley   +1 more source

Community-based HyPertension Control (CHPC) in Nepal: Cluster randomized implementation trial protocol. [PDF]

Public Health Pract (Oxf)
Shrestha A, Sapkota S, Timalsena D, Sharma P, Porter AK, Cameron DB, Hagaman A, Neupane D, Dhimal M, Mali S, Poudel L, Sagtani RA, Paneru B, Paudel P, Joshi A, Chaulagain DR, Karmacharya RM, Spiegelman D.   +17 more
europepmc   +1 more source

GelMA‐based 3D spheroids recapitulate transcriptomic and functional hallmarks of myeloid sarcoma

FEBS Open Bio, EarlyView.
GelMA 5% hydrogels support the formation of myeloid leukemia spheroids that recapitulate MS‐specific features, including G1 arrest, apoptosis, and ECM‐driven transcriptomic reprogramming. The 3D model mimicked soft‐tissue‐like stiffness and oxygen conditions, and transcriptomic convergence with primary MS samples confirmed its utility as a preclinical ...
Nicolas Germain, Elise Buret, Le Hoang Thanh Nguyen, Marion Cocheteux, Nicolas Touya, Mélanie Dhayer, Romain Dubois, Frank Lafont, Sebastien Janel, Patrice Maboudou, Steve Lancel, Philippe Marchetti   +11 more
wiley   +1 more source

Reply: Cost-utility Analysis of Ligament Reconstruction Tendon Interposition versus Suture Suspension Arthroplasty for Thumb Osteoarthritis. [PDF]

Plast Reconstr Surg Glob Open
Wong CR, Baltzer HL.
europepmc   +1 more source