Results 91 to 100 of about 4,232,012 (302)

A Methodological Approach to Assessing Constructability in Building Maintenance and Its Impact on University Quality

open access: yesBuildings
This study introduces and evaluates an innovative methodology for assessing constructability in the maintenance of university buildings, aiming to improve the quality of academic infrastructure.
Mónica Escate, Doris Esenarro
doaj   +1 more source

Scenarios for Maintenance and Building Decommissioning in the Building’s Life Cycle

open access: yesIOP Conference Series: Earth and Environmental Science, 2019
The LCC analysis can be applied to assess effectiveness of construction variants or acquisition of new facilities as well as modernization of the existing ones. The authors of this paper intended to apply the LCCA method at analysing a building in the final stage of the building life cycle (grade phase).
E. Plebankiewicz, K. Zima, D. Wieczorek
openaire   +2 more sources

Structure‐forward targeting of claudins with synthetic binders

open access: yesFEBS Letters, EarlyView.
Claudins form the paracellular barriers between epithelial and endothelial tissues at tight junctions and are targets for molecular binders with the goal of modulating barrier permeability. Claudin‐binding molecules are relevant in drug delivery or in altering claudin interactions with disease‐causing proteins.
Alex J. Vecchio
wiley   +1 more source

Assessment of the Effects of Deferred Maintenance on the Current Technical Condition of a Building: Case Study—A Former Fire Station in Nowy Raduszec

open access: yesApplied Sciences
The degradation of building elements progresses with the age of a building as a result of natural ageing processes. The lack of regular maintenance, repair, and renovation works during the operational phase accelerates degradation processes, leading to ...
Aleksandra Kurowska-Rajchel   +1 more
doaj   +1 more source

Influence of Climate Conditions on Deficiencies of Building Roofs

open access: yesApplied Sciences, 2019
Climate conditions affect buildings’ performance and durability. The purpose of this paper is to examine the influence of climate conditions on roof deficiencies. 763 cases of such deficiencies were analyzed in this regard.
Manuel J. Carretero-Ayuso   +2 more
doaj   +1 more source

Study on the Construction Performance of Zeolite Asphalt Mixture Based on Macro-Micro Scale

open access: yesAdvances in Materials Science and Engineering, 2020
In order to explore the construction performance of zeolite asphalt mixture, the microproperties of zeolite and the macroproperties of zeolite asphalt mixture were studied.
Zhuolin Li   +5 more
doaj   +1 more source

Building Facade Maintenance

open access: yesVestnik Tomskogo gosudarstvennogo arkhitekturno-stroitel'nogo universiteta. JOURNAL of Construction and Architecture
The article is devoted to the problem of providing access to building facades in order to maintain their operational characteristics.Purpose: The purpose of the study is to identify general principles of building facade maintenance that contribute to typification and unification of solutions, and develop practical recommendations for their application ...
L. D. Morshakova   +2 more
openaire   +1 more source

Peripheral lysosomes recruit PLEKHG3 to focal adhesions and restrain protrusion dynamics

open access: yesFEBS Letters, EarlyView.
Proximity‐dependent labeling at the LAMTOR complex revealed the Rho GEF PLEKHG3 as a lysosome‐proximal protein directing the study toward the influence of lysosome positioning on actin dynamics and cell motility. We show that PLEKHG3 colocalizes with lysosomes at focal adhesion sites and observe that forced peripheral dispersion of lysosomes hinders ...
Rainer Ettelt   +8 more
wiley   +1 more source

Buildings Lean Maintenance Implementation Model

open access: yesOpen Engineering, 2016
Abstract Nowadays, companies in global markets have to achieve high levels of performance and competitiveness to stay “alive”.Within this assumption, the building maintenance cannot be done in a casual and improvised way due to the costs related.
Abreu, António   +2 more
openaire   +3 more sources

Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation

open access: yesFEBS Letters, EarlyView.
Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang   +2 more
wiley   +1 more source

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