Results 71 to 80 of about 4,471,776 (304)

Investigating transcription factor dynamics in health and disease using FRAP

FEBS Letters, EarlyView.
FRAP analysis of GFP‐tagged transcription factors reveals how molecular mobility and target engagement change in response to drug treatment. By combining live‐cell imaging, quantitative model fitting, and statistical analysis, this approach uncovers transcription factor dynamics linked to disease mechanisms, providing a powerful framework for ...
Kannan Govindaraj, Carolina Vazquez Garzon, Jose Joaquin Velasco, Janine N. Post   +3 more
wiley   +1 more source

Post-Occupancy Evaluation Data Support for Planning and Management of Building Maintenance Plans

Buildings, 2016
The purpose of this paper is to propose a post-occupancy evaluation (POE) method focused on building maintenance and then to test it on two different sets of residential buildings.
Nelson Bento Pereira, Rui Calejo Rodrigues, Patrícia Fernandes Rocha   +2 more
doaj   +1 more source

Conserved binding mode but diverse interfaces of MreC‐PBP2 interactions

FEBS Letters, EarlyView.
The crystal structure of abMreC reveals a conserved two β‐barrel architecture and provides structural insights into its role within the bacterial elongasome. The abMreC–abPBP2 complex model identifies the molecular basis of MreC‐mediated PBP2 recognition, contributing to the regulation of peptidoglycan synthesis.
Hyunseok Jang, Hyo Been Jin, Chang Min Kim, So Yeon Lee, Hyun Ho Park   +4 more
wiley   +1 more source

Analysis of building maintenance process solutions in the management of commercial real estate

Mokslas: Lietuvos Ateitis
Building maintenance is one of the key areas of real estate management, ensuring the technical reliability of buildings, user safety, and the preservation of long-term asset value.
Stanislavas Ženauskas
doaj   +1 more source

Structure‐forward targeting of claudins with synthetic binders

FEBS Letters, EarlyView.
Claudins form the paracellular barriers between epithelial and endothelial tissues at tight junctions and are targets for molecular binders with the goal of modulating barrier permeability. Claudin‐binding molecules are relevant in drug delivery or in altering claudin interactions with disease‐causing proteins.
Alex J. Vecchio
wiley   +1 more source

Adopting green building constructions in developing countries through capacity building strategy: survey of Enugu State, Nigeria

Sustainable Buildings, 2019
Green building (GB) constructions seeks to address housing demands of the growing populace with better qualities, energy efficiency, using recycled and recyclable materials, improve building lifespan and health of occupants.
Chukwu Daniel Uchenna, Anaele Edmund A., Omeje Hyginus O., Ohanu Ifeanyi B.   +3 more
doaj   +1 more source

Building Maintenance

, 2009
Maintaining a building is expensive: it costs many times more to run a building than to build it, yet maintenance is often accorded a low priority. Building Maintenance covers the technical aspects of maintenance for undergraduate students on built ...
Wood, Brian
core  

Strategies of Public University Building Maintenance—A Literature Survey

In this article, comprehensive insights into the field of building maintenance, emphasizing the importance of keywords, collaborative efforts among authors, and the evolving research landscape, are provided.
Edyta Plebankiewicz, Jakub Grącki
core   +1 more source

Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation

FEBS Letters, EarlyView.
Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang, Ruslana Romaniuk, Hristo L. Svilenov   +2 more
wiley   +1 more source

A service-life cycle approach to maintenance and energy retrofit planning for building portfolios [PDF]

, 2019
\ua9 2019 The Authors Residential buildings account for almost a quarter of the total energy use in Sweden and building owners are, therefore, under pressure from policy makers to improve the energy performance of their buildings.
Wallbaum, Holger,, Sousanabadi Farahani, Abolfazl, Wallbaum, Holger, Dalenb\ue4ck, Jan-Olof, 6sterbring, Magnus, Dalenbäck, Jan-Olof,, N\ue4geli, Claudio, Sousanabadi Farahani, Abolfazl,, Österbring, Magnus,, Nägeli, Claudio,   +9 more
core   +1 more source