Results 61 to 70 of about 8,855,802 (295)
FEBS Letters, EarlyView.CT10 regulator of kinase (CRK) and CRK‐Like (CRKL) are signaling adaptors driving cell adhesion, motility, differentiation, and proliferation. SH2‐domain containing (SH) proteins are enriched in YXXP motifs which when phosphorylated create preferred binding sites for CRK family SH2 domains.
Phoebe M. Cousens +8 more
wiley +1 more source
Building Materials and Construction: The Four Building Challenges
, 2018 The chapter analyses the radical changes in the supply chain of building materials and construction between 1850 and 1910. It investigates the consequences for the four building challenges in this period: public hygiene, public housing, the struggle against water and the development of road infrastructure.
openaire +2 more sources
Reconstructing enzyme evolution by protein engineering
FEBS Letters, EarlyView.Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler +2 more
wiley +1 more source
Framework to Model Building Carbon Emissions [PDF]
As part of the DynamicRenowave project on life cycle assessment and energy simulation of building renovation strategies activities, a new modeling framework has been created.
Bertini, Aurora +10 more
core +1 more source
Strengthening properties of glass-ceramics with near-zero thermal expansion
Materials & DesignThe hydrogen atomic clock microwave cavity serves as the interaction site between electromagnetic fields and hydrogen atoms, requiring materials with low coefficient of thermal expansion, high temperature variation resistance, and superior mechanical ...
Shengyun Yang +9 more
doaj +1 more source
Investigating transcription factor dynamics in health and disease using FRAP
FEBS Letters, EarlyView.FRAP analysis of GFP‐tagged transcription factors reveals how molecular mobility and target engagement change in response to drug treatment. By combining live‐cell imaging, quantitative model fitting, and statistical analysis, this approach uncovers transcription factor dynamics linked to disease mechanisms, providing a powerful framework for ...
Kannan Govindaraj +3 more
wiley +1 more source
Influence of additives on flexural strength of concrete
MATEC Web of Conferences, 2017 In earlier studies, the effect of chemical and mineral additives on the compressive strength of concretes was considered, but little attention was paid to the flexural strength of concrete.
Tolmachov Sergii +2 more
doaj +1 more source
Recent Advances in Phenylboronic Acid-Based Gels with Potential for Self-Regulated Drug Delivery
Molecules, 2019 Glucose-sensitive drug platforms are highly attractive in the field of self-regulated drug delivery. Drug carriers based on boronic acid (BA), especially phenylboronic acid (PBA), have been designed for glucose-sensitive self-regulated insulin delivery ...
Chenyu Wang +7 more
doaj +1 more source
Structure‐forward targeting of claudins with synthetic binders
FEBS Letters, EarlyView.Claudins form the paracellular barriers between epithelial and endothelial tissues at tight junctions and are targets for molecular binders with the goal of modulating barrier permeability. Claudin‐binding molecules are relevant in drug delivery or in altering claudin interactions with disease‐causing proteins.
Alex J. Vecchio
wiley +1 more source
High performance building envelopes with retro-reflective materials
, 2017 Highly reflective materials have been proposed as a strategy for energy consumption reduction in buildings and outdoor comfort improvement (i.e. urban heat island mitigation).
CASTELLANI, BEATRICE +4 more
core