Results 61 to 70 of about 8,702,044 (298)

Reconstructing enzyme evolution by protein engineering

FEBS Letters, EarlyView.
Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler, Markus R. Busch, Reinhard Sterner   +2 more
wiley   +1 more source

The Energy Impact of Building Materials in Residential Buildings in Turkey

, 2021
In Turkey, heat loss from existing and new buildings constitutes a large part of energy waste, so usage of suitable construction material is quite important.
Pınar Usta, Başak Zengin
core   +1 more source

Nanoproducts in Building Materials

Abstract The second chapter is dedicated to an exhaustive elucidation and evaluation of the deployment of nanoproducts in materials integral to the construction sector. This includes a precise definition of the primary nanoproducts prevalent in this sector, accompanied by an in-depth analysis of their most prevalent characterization ...
Porras Pereira, Paula, Llorente-García, Juana Esperanza, Charitidis, Costas A.   +2 more
openaire   +1 more source

Investigating transcription factor dynamics in health and disease using FRAP

FEBS Letters, EarlyView.
FRAP analysis of GFP‐tagged transcription factors reveals how molecular mobility and target engagement change in response to drug treatment. By combining live‐cell imaging, quantitative model fitting, and statistical analysis, this approach uncovers transcription factor dynamics linked to disease mechanisms, providing a powerful framework for ...
Kannan Govindaraj, Carolina Vazquez Garzon, Jose Joaquin Velasco, Janine N. Post   +3 more
wiley   +1 more source

Extraction of Alkalis from Silicate Materials PART 2—Crystalline Silicate Materials

, 2022
A feature of silicate materials is that they can exist in two antagonistic states—amorphous and crystalline. In both cases, alkalis, which are always present in chemical compositions, play an important role.
Galyna Kotsay, Kotsay, Galyna, Szewczenko, Wiktor, Wiktor Szewczenko   +3 more
core   +1 more source

Influence of Propagation Distance on Characteristic Parameters of Acoustic Emission Signals in Concrete Materials Based on Low-Frequency Sensor

Advances in Civil Engineering, 2022
Acoustic emission is a nondestructive testing technology based on the propagation of transient elastic waves captured by acoustic emission sensors. The acoustic emission signal depends not only on the distance and quality of the propagation path of the ...
Fen Liu, Rui Guo, Xiujuan Lin, Xiaofang Zhang, Shifeng Huang, Feng Yang, Xin Cheng   +6 more
doaj   +1 more source

Structure‐forward targeting of claudins with synthetic binders

FEBS Letters, EarlyView.
Claudins form the paracellular barriers between epithelial and endothelial tissues at tight junctions and are targets for molecular binders with the goal of modulating barrier permeability. Claudin‐binding molecules are relevant in drug delivery or in altering claudin interactions with disease‐causing proteins.
Alex J. Vecchio
wiley   +1 more source

The Validation and Discussion of a Comparative Method Based on Experiment to Determine the Effective Thickness of Composite Glass

Buildings
This study introduces and validates a comparative experiment-based method for determining the effective thickness of composite glass, including polymeric laminated glass (with polyvinyl butyral (PVB) and SentryGlas® (SGP) interlayers) and vacuum glazing.
Dake Cao, Xiaogen Liu, Zhe Yang, Jiawei Huang, Ming Xu, Detian Wan   +5 more
doaj   +1 more source

Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation

FEBS Letters, EarlyView.
Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang, Ruslana Romaniuk, Hristo L. Svilenov   +2 more
wiley   +1 more source

Near-Infrared Absorption Enhancement of GaAs Photocathode Through “Sandwich” Micro-Nano Structure

Photonics
In this paper, a nano-layered transmission GaAs photocathode structure is proposed. The near-infrared absorption of the photocathode is enhanced by inserting a “sandwich” structure of nano-SiO2 layer + Si3N4 nanopillar array + nano-SiO2 layer between the
Ziyang Xiao, Miao Dong, Yonggang Huang, Jinhui Yang, Peng Jiao, Pan Shi, Yajie Du, Ying He, Jing Cheng, Yinsheng Xu   +9 more
doaj   +1 more source