Results 141 to 150 of about 67,161 (299)

Tumor‐Intrinsic ARHGEF3 Enhances Antitumor Immunity by Promoting T‐Cell Infiltration and Limiting Myeloid Cell‐Mediated Immunosuppression

open access: yesAdvanced Science, EarlyView.
ARHGEF3 is broadly downregulated across human cancers and correlates with patient prognosis. Tumor‐intrinsic ARHGEF3 activates the RHOA–ROCK–PTEN cascade to inhibit AKT signaling, thereby promoting chemokine‐driven T‐cell infiltration and relieving lipid‐mediated myeloid immunosuppression.
Yue Li   +8 more
wiley   +1 more source

[Stone building adjacent to ruins]

open access: yes, 1966
This photograph is from a Texas Boys Choir trip. Photograph of a well maintained stone building with a grassy lawn in front of it.

core   +1 more source

Dynamic Etching‐Induced Cl‐Terminated Ti3C2Clx/Ti3ZnC2 Heterostructure for Ammonia Electrosynthesis and Zinc‐Nitrogen Batteries

open access: yesAdvanced Science, EarlyView.
A stable Ti3C2Clx/Ti3ZnC2 heterostructure, fabricated by dynamic etching, exhibits outstanding electrocatalytic NRR activity (NH3 yield: 20.1 µg h−1 mg−1, FE: 38.1%) in alkaline media. The corresponding Zn‐N2 battery achieves a peak power density of 36.5 µW cm−2 and an NH3 yield of 13.1 µg h−1 mg−1, providing an advanced strategy for NH3 and ...
Yu Wang   +9 more
wiley   +1 more source

Natural stone deposits in an assemblage of subhorizontal intrusions - The Kuru granite batholith [PDF]

open access: yesBulletin of the Geological Society of Finland, 2012
O. Selonen   +3 more
doaj   +1 more source

Quantifying sorptivity using the contact sponge method: an improved calculation method validated by classical capillary rise experiments and neutron radiography. [PDF]

open access: yesMater Struct
Derluyn H   +8 more
europepmc   +1 more source

Engineering an Optogenetic pH‐Modulator in Bacteria

open access: yesAdvanced Science, EarlyView.
ABSTRACT Cells in many naturally occurring organisms routinely cooperate to control their extracellular pH in a dynamic and reversible manner, but this capability has been underexplored in synthetic biology. Here, we sought to engineer a microbial system that switches between two states —high and low extracellular pH— with minimal human intervention ...
Jenevieve Kuang   +7 more
wiley   +1 more source

Secreted Nonstructural Protein 3 is a Pathogenic Determinant of Orbivirus

open access: yesAdvanced Science, EarlyView.
This study uncovers a conserved PIP2‐dependent secretory pathway of orbivirus NS3 that induces vascular leakage. Pharmacological disruption of PIP2‐NS3 interaction significantly reduces viral pathogenicity and provides protective efficacy in murine models, establishing PIP2‐mediated NS3 secretion as both a key virulence determinant and a promising ...
Junyong Guan   +11 more
wiley   +1 more source

Faster and Durable: A Cell‐to‐System Validation of a Low‐Degradation Fast‐Charge Protocol for Li‐Ion Batteries

open access: yesAdvanced Science, EarlyView.
A physics‐based framework resolving graphite phase‐separation dynamics establishes a predictive, degradation‐aware fast‐charging methodology for commercial Li‐ion batteries. The resulting model‐informed protocol achieves 20%–80% state‐of‐charge in 14 min while matching the long‐term degradation of a commercial 25‐minute EV strategy.
Marco Lagnoni   +10 more
wiley   +1 more source

Home - About - Disclaimer - Privacy