Results 221 to 230 of about 7,009,009 (308)

Assessing the Generalizability of Machine Learning and Physics-Based Methods with DNA-Encoded Libraries. [PDF]

J Chem Inf Model
Dolorfino M, Santos Perez D, Fu Y, Lin SH, McCarty S, O'Meara MJ, Sztain T.   +6 more
europepmc   +1 more source

Recent insights into the molecular mechanism of ubiquinol oxidation by cytochrome bc1

FEBS Open Bio, EarlyView.
The review reflects on the mechanism of the catalytic reaction in cytochrome bc1: the electron bifurcation that involves the separation of two electrons derived from the quinol oxidation to opposite sides of the enzyme across the membrane. This review summarizes the long‐standing effort to understand the mechanism of quinol oxidation catalyzed by ...
Anna Wójcik‐Augustyn, Artur Osyczka, Marcin Sarewicz   +2 more
wiley   +1 more source

Data analysis of experimentally solved nucleosome arrays reveals heterogeneous features. [PDF]

Nucleic Acids Res
Portillo-Ledesma S, Li Z, Franowicz E, Schlick T.   +3 more
europepmc   +1 more source

Building Structured Theories [PDF]

, 2011
openaire   +1 more source

Identification and characterization of a gene conferring stress resistance in Escherichia coli and cyanobacteria

FEBS Open Bio, EarlyView.
Functional screening identified PcSyn14890, a cyanobacteria‐specific protein that enhances growth and stress resistance in E. coli and Synechocystis PCC6803. Although we expected it to function as a molecular chaperone, it was unable to protect against thermal aggregation of GAPDH.
Akiyo Yamada, Takaaki Tanaka, Manaka Uehara, Keigo Nakano, Ken Morishima, Rintaro Inoue, Masaaki Sugiyama, Masafumi Yohda   +7 more
wiley   +1 more source

Unbiased Structure Prediction of Sophisticated Cage Structures. [PDF]

Angew Chem Int Ed Engl
Tarzia A, Pavan GM.
europepmc   +1 more source

Using fluorescence fluctuation spectroscopy to quantify molecular dynamics within cells

FEBS Open Bio, EarlyView.
Microscopy techniques like fluorescence correlation spectroscopy (FCS) and number and brightness analysis (N&B) allow to quantify concentrations, diffusion rates, and oligomerization of fluorescently labeled molecules in the living cell. In this protocol the principles of how to set up these types of experiments are described including calibration ...
Mark A. Hink
wiley   +1 more source

Modular assembly and property profiling of an expansive, shape-defined library of pentacyclic saturated N-heterocycles. [PDF]

Chem Sci
Boschi E, Mazunin D, Mueller A, Zimmerli D, Wechsler D, Ebert MO, Bartelmus C, Binder M, Wagner B, Weinmann C, Kroll C, Haap W, Bode JW.   +12 more
europepmc   +1 more source

Characterization of the key membrane protein cytochrome Cyc2 from Ghiorsea bivora

FEBS Open Bio, EarlyView.
This study reports the first detailed biochemical analysis of Cyc2TAG1_1, a cytochrome protein involved in microbial iron oxidation. We produced and purified this enzyme in E. coli, then measured its iron‐oxidizing efficiency, and characterized its electrical and structural properties.
Josiane Azizi, Alain Dolla, Frauke Baymann, Celine Rommevaux, Latifa Elantak, Helene Gaussier, Matthieu Nouailler   +6 more
wiley   +1 more source

Automating Model Building for SPM Images of Biomolecules Using MISO. [PDF]

J Chem Inf Model
Gomez-Flores CL, Anggara K.
europepmc   +1 more source