Results 51 to 60 of about 317,136 (266)
Calpain small subunit homodimerization is robust and calcium‐independent
Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy +4 more
wiley +1 more source
SURVEY OF HISTORICAL HOUSES IN THE ETHNOGRAPHIC MUSEUM OF TRANSYLVANIA "ROMULUS VUIA" CLUJ-NAPOCA
A measured drawing is a precise one, to scale, which accurately shows the real situation of the investigated building. Historical architecture of interest for cultural heritage deserves to be documented whenever we have this possibility, and the 1st ...
Dana Sorina OPINCARIU +2 more
doaj +2 more sources
Structural insights into an engineered feruloyl esterase with improved MHET degrading properties
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa +5 more
wiley +1 more source
Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura +2 more
wiley +1 more source
Foaling rates in feral horses treated with the immunocontraceptive porcine zona pellucida
Locally abundant feral horses (Equus caballus) can rapidly deplete available resources. Fertility control agents present promising nonlethal tools for reducing their population growth rates.
Jason I. Ransom +4 more
doaj +1 more source
ANCIENT MINING LANDSCAPES AND HABITATIVE SCENERIES IN THE URBAN AREA OF CENTOCELLE: GEOMATIC APPLICATIONS FOR THEIR IDENTIFICATION, MEASUREMENT, DOCUMENTATION AND MONITORING [PDF]
This study, focused on the Archaeological Park of Centocelle, was carried out to test the functionality of different geomatic products for the identification and monitoring of complex archaeological evidences in urban areas.
A. Celauro +8 more
doaj +1 more source
The Building Principal in the Surveys [PDF]
"As is the principal, so is the school," wrote Chancellor Elliott in the report of the New York school survey. The principal is near enough to the actual teaching to control detailed procedure, to adapt it to the special needs of his district, and to keep the work on a high plane of efficiency.
openaire +1 more source
Diversity and complexity in neural organoids
Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley +1 more source
Biodiversity is threatened due to land-use change, overexploitation, pollution, and anthropogenic climate change, altering ecosystem functioning around the globe.
Cameron L. Aldridge +5 more
doaj +1 more source
Plasma membranes contain dynamic nanoscale domains that organize lipids and receptors. Because viruses operate at similar scales, this architecture shapes early infection steps, including attachment, receptor engagement, and entry. Using influenza A virus and HIV‐1 as examples, we highlight how receptor nanoclusters, multivalent glycan interactions ...
Jan Schlegel, Christian Sieben
wiley +1 more source

