Results 91 to 100 of about 407,912 (312)

An unexpected alternative viologen electron mediator site in tungsten‐containing formate dehydrogenase

open access: yesFEBS Letters, EarlyView.
An unexpected alternative interaction site for ethyl viologen was identified in formate dehydrogenase 1 from Methylorubrum extorquens. Combined mutagenesis, kinetic analysis, and docking revealed that aromatic residues near an iron–sulfur cluster enable flavin mononucleotide‐independent electron transfer, offering a framework for engineering improved ...
Eleni G. Poloniataki, Yong Hwan Kim
wiley   +1 more source

A Comparison of Capacitive Soil Moisture Sensors in Different Substrates for Use in Irrigation Systems

open access: yesSensors
Smart irrigation systems play a crucial role in water management, particularly in urban greening applications aimed at mitigating urban heat islands and enhancing environmental sustainability. These systems rely on soil moisture sensors to optimize water
Mehmet Akif Gümüser   +2 more
doaj   +1 more source

Building a Dictionary using XML Technology.

open access: yes, 2016
In this article we describe the workflow implemented to convert a dictionary saved as a PDF file into an XML document and posterior importation into an XML aware database, and the process to edit, add and delete new entries. The conversion process was challenging given the format of the PDF file, and the fine grained detail of the XML schema that was ...
Alberto Simões 0001   +2 more
openaire   +4 more sources

Ubiquitination of secretory granules promotes their crinophagic degradation in Drosophila

open access: yesFEBS Letters, EarlyView.
Ubiquitination of secretory granules in Drosophila larval salivary glands is a critical molecular trigger for crinophagy, the lysosomal degradation of unreleased, or low‐quality granules. The E3 ubiquitin ligase Cnot4 is recruited to the surface of secretory granules to induce crinophagy.
Tamás Csizmadia   +6 more
wiley   +1 more source

Building America Technical Highlight Fact Sheets

open access: yes, 2011
This technical highlight describes NREL research to develop a set of diagnostic test cases for building energy simulations in order to achieve more accurate energy use and savings predictions.

core   +1 more source

Network divergence analysis identifies adaptive gene modules and two orthogonal vulnerability axes in pancreatic cancer

open access: yesMolecular Oncology, EarlyView.
Tumors contain diverse cellular states whose behavior is shaped by context‐dependent gene coordination. By comparing gene–gene relationships across biological contexts, we identify adaptive transcriptional modules that reorganize into distinct vulnerability axes.
Brian Nelson   +9 more
wiley   +1 more source

Ambient Games, Revealing a Route to a World Where Work is Play?

open access: yesInternational Journal of Computer Games Technology, 2008
A novel way of playing games called ambient gaming is defined and described. Growing out of ideas in ambient music, ambient gaming is defined as “ignorable as it is interesting” after Brian Eno's description of ambient music. Ambient gaming is set in the
Mark Eyles, Roger Eglin
doaj   +1 more source

Outdoor Airflow Into HVAC Systems: An Evaluation of Measurement Technologies [PDF]

open access: yes, 2003
During the last few years, new technologies have been introduced for measuring the flow rates of outdoor air (OA) into HVAC systems; however, an evaluation of these measurement technologies has not previously been published.
Fisk, William J.   +3 more
core   +1 more source

COMP–PMEPA1 axis promotes epithelial‐to‐mesenchymal transition in breast cancer cells

open access: yesMolecular Oncology, EarlyView.
This study reveals that cartilage oligomeric matrix protein (COMP) promotes epithelial‐to‐mesenchymal transition (EMT) in breast cancer. We identify PMEPA1 (protein TMEPAI) as a novel COMP‐binding partner that mediates EMT via binding to the TSP domains of COMP, establishing the COMP–PMEPA1 axis as a key EMT driver in breast cancer.
Konstantinos S. Papadakos   +6 more
wiley   +1 more source

Engineered extracellular vesicles enriched with the miR‐214/199a cluster enhance the efficacy of chemotherapy in ovarian cancer

open access: yesMolecular Oncology, EarlyView.
Loss of the miR‐214/199a cluster is associated with recurrence in ovarian cancer. Engineered small extracellular vesicles (m214‐sEVs) elevate miR‐214‐3p/miR‐199a‐5p in tumor cells, suppress β‐catenin, TLR4, and YKT6 signaling, reprogram tumor‐derived sEV cargo, reduce chemoresistance and migration, and enhance carboplatin efficacy and survival in ...
Weida Wang   +12 more
wiley   +1 more source

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