Results 181 to 190 of about 2,125,522 (310)

Reframing involuntary treatment as a sentinel event: a model for improving rights-based mental health care. [PDF]

Front Psychiatry
Cossu G, Atzeni M, Zreik T, Tusconi M, Carta MG.   +4 more
europepmc   +1 more source

SmallTalk: a novel small‐sized fusion tag for peptide expression and purification

FEBS Open Bio, EarlyView.
The SmallTalk fusion tag allows for the efficient expression and purification of soluble recombinant proteins or peptides in Escherichia coli. Testing with SmallTalk‐GFP confirmed that the proteins were soluble and folded correctly, while SmallTalk‐Bin1b maintained its antimicrobial activity against various bacterial isolates. This streamlined workflow
Atika Tariq, Nestor G. Casillas‐Vega, Alma Gomez‐Loredo, Xristo Zarate   +3 more
wiley   +1 more source

New WHO guidance on mental health and well-being across government sectors. [PDF]

World Psychiatry
Funk M, Drew N, Cole C, Moro MF.
europepmc   +1 more source

Using measured equipment load profiles to "right-size" HVAC systems and reduce energy use in laboratory buildings (Pt. 2)

, 2008
There is a general paucity of measured equipment load data for laboratories and other complex buildings and designers often use estimates based on nameplate rated data or design assumptions from prior projects. Consequently, peak equipment loads are frequently overestimated, and load variation across laboratory spaces within a building is typically ...
Mathew, Paul, Greenberg, Steve, Frenze, David, Morehead, Michael, Sartor, Dale, Starr, William   +5 more
openaire   +1 more source

Autophagosome marker, LC3, is released extracellularly via several distinct pathways

FEBS Open Bio, EarlyView.
This study establishes a novel HiBiT‐tagging system for ultrasensitive detection of LC3, revealing multiple pathways for its extracellular secretion. It demonstrates that LC3 is released via both autophagy‐dependent and ‐independent mechanisms, including a novel route for nonlipidated LC3‐I.
Koki Saito, Masashi Arakawa, Koki Maeda, Eiji Morita   +3 more
wiley   +1 more source

Navigating new norms: a systematic review of factors for the development of effective digital tools in higher education

FEBS Open Bio, EarlyView.
What factors make for an effective digital learning tool in Higher Education? This systematic review identifies elements of a digital tool that published examples reveal to be features of an engaging and impactful digital tool. A systematic literature search yielded 25 research papers for analysis.
Akmal Arzeman, Jessica Haines, Connie Pritchard, Stephen Rutherford, Nigel Francis   +4 more
wiley   +1 more source

Enhancing healthcare access for persons with disabilities: lessons from partnerships between organisations of persons with disabilities and international non-governmental organisations. [PDF]

Int Health
Hall P, Walsh C, Elliott C, Trimmel J.
europepmc   +1 more source

Establishment of a coculture system for Porphyromonas gingivalis and head and neck squamous cell carcinoma using spheroid culture and LATS inhibition

FEBS Open Bio, EarlyView.
We established a spheroid coculture system enabling viable Porphyromonas gingivalis–HNSCC interactions under normoxic conditions. Inhibition of LATS1/2 maintains tumor cells in an undifferentiated state, which may promote spheroid growth and create a more permissive environment for bacterial persistence.
Yurika Nakajima, Shogo Okazaki, Muneaki Tamura, Shuichi Sato, Kenichi Imai   +4 more
wiley   +1 more source

The United Nations convention on rare diseases-A framework for research prioritization. [PDF]

Front Public Health
Junaid M, Downs J, Groza T, Lassmann T, Baker S, Stevens K, Keeffe J, Gration D, Newell A, Duckers J, Baynam G.   +10 more
europepmc   +1 more source

Antibiofilm activity of a chionodracine‐derived peptide by NMR‐based metabolomics of cell‐free supernatant of Acinetobacter baumannii clinical strains

FEBS Open Bio, EarlyView.
KHS‐Cnd peptide is able to impair biofilm formation and disaggregate mature biofilms in Acinetobacter baumannii clinical isolates. Differences in extracellular metabolites reflect changes in biofilm metabolism due to KHS‐Cnd treatment. Among the differentially represented extracellular metabolites upon KHS‐Cnd treatment, the significantly altered ...
Fernando Porcelli, Enrico Landi, Francesco Maiurano, Irene Paris, Rosanna Papa, Marco Artini, Laura Selan, Stefano Borocci, Francesco Buonocore, Esther Imperlini   +9 more
wiley   +1 more source