Results 271 to 280 of about 366,637 (312)

Radial Velocity Monitoring and Analysis of Gaia Astrometry of Selected Intermediate Mass Stars to Constrain Their Multiplicity Status

open access: yesAstronomische Nachrichten, EarlyView.
ABSTRACT We present new radial velocity measurements of 13 selected intermediate mass stars (2–6 M⊙). The measurements were performed between 29 April and 6 September 2024 at the University Observatory Jena using the échelle spectrograph FLECHAS. The radial velocity of eight stars was found to be constant during our spectroscopic monitoring, namely: 17
J. Bätz   +7 more
wiley   +1 more source

Validation of phiC31-mediated expression and functional knockout of Opn3 in the Opn3-phiC31o knock-in mouse. [PDF]

open access: yesEye Vis (Lond)
Kwok RKY   +10 more
europepmc   +1 more source

Switching disease‐modifying therapies in patients with spinal muscular atrophy: A systematic review on effectiveness outcomes

open access: yesBritish Journal of Clinical Pharmacology, EarlyView.
With multiple disease‐modifying therapies now available, treatment switching has become an important clinical consideration in the management of spinal muscular atrophy (SMA). While some switches are prompted by suboptimal clinical response, more commonly they are driven by treatment burden, convenience, or adverse events.
Andrej Belančić   +4 more
wiley   +1 more source

The effect of chronic stress and chronic alcohol intake on behaviour, brain volume, and functional connectivity in a longitudinal rat model. [PDF]

open access: yesBrain Commun
Rasgado-Toledo J   +13 more
europepmc   +1 more source

Delivery strategies of messenger RNA therapeutics for brain disorders

open access: yesBulletin of the Korean Chemical Society, EarlyView.
Thus, mRNA therapeutics offer a powerful new avenue for the treatment of brain diseases. This review examines strategies to bypass biological barriers, particularly the blood–brain barrier, and explores emerging delivery systems, such as direct intracerebral injection, intracerebroventricular injection, systemic delivery (including intravenous ...
Kounghwa Youn   +5 more
wiley   +1 more source

Acute Otomastoiditis in Children: An Observational Study on the Role of Mastoid Morphology in the Development of Intracranial Complications. [PDF]

open access: yesJ Clin Med
Russo C   +14 more
europepmc   +1 more source

Nanostructured drug delivery systems for posterior segment eye diseases: Strategies to defy ocular barriers

open access: yesBMEMat, EarlyView.
Efficient drug delivery to the posterior segment of the eye has long been a challenging issue due to the complex ocular barriers. The review focuses on the promise held by nanoplatforms for barrier penetration and the key mechanisms involved, also highlighting their advantages in achieving efficient drug delivery and superior treatment of PSEDs ...
Yifan Shen   +7 more
wiley   +1 more source

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