Results 11 to 20 of about 485 (123)

Microstructural plasticity in nociceptive pathways after spinal cord injury. [PDF]

, 2021
OBJECTIVE To track the interplay between (micro-) structural changes along the trajectories of nociceptive pathways and its relation to the presence and intensity of neuropathic pain (NP) after spinal cord injury (SCI).
Ashburner, John, Azzarito, Michela, Blaiotta, Claudia, Calhoun, Vince D, Freund, Patrick, Friston, Karl, Kyathanahally, Sreenath P, Rosner, Jan, Weiskopf, Nikolaus, Wiech, Katja, Ziegler, Gabriel   +10 more
core   +4 more sources

Impaired Nuclear Export of Polyglutamine-Expanded Androgen Receptor in Spinal and Bulbar Muscular Atrophy. [PDF]

, 2019
Spinal and bulbar muscular atrophy (SBMA) is a neuromuscular disease caused by polyglutamine (polyQ) expansion in the androgen receptor (AR). Prior studies have highlighted the importance of AR nuclear localization in SBMA pathogenesis; therefore, in ...
Arnold, Frederick J., Merry, Diane E., Pluciennik, Anna   +2 more
core   +3 more sources

Brown-Vialetto-Van Laere syndrome [PDF]

, 2008
The Brown-Vialetto-Van Laere syndrome (BVVL) is a rare neurological disorder characterized by progressive pontobulbar palsy associated with sensorineural deafness. Fifty-eight cases have been reported in just over 100 years.
Sivakumar Sathasivam
core   +1 more source

Early stages of building a rare disease registry, methods and 2010 data from the Belgian Neuromuscular Disease Registry (BNMDR) [PDF]

, 2015
The Belgian Neuromuscular Disease Registry, commissioned in 2008, aims to collect data to improve knowledge on neuromuscular diseases and enhance quality health services for neuromuscular disease patients.
BNMDR Scientific Committee, the, De Bleecker, Jan, Doggen, Kris, Roy, Anna J, Van Casteren, Viviane, Van Coster, Rudy, Van Damme, Philip, Van den Bergh, Peter   +7 more
core   +2 more sources

Strategies to augment volitional and reflex function may improve locomotor capacity following incomplete spinal cord injury [PDF]

, 2018
Many studies highlight the remarkable plasticity demonstrated by spinal circuits following an incomplete spinal cord injury (SCI). Such plasticity can contribute to improvements in volitional motor recovery, such as walking function, although similar ...
Hornby, T. George, Kim, Hyosub E., Leech, Kristan A.   +2 more
core   +2 more sources

Nuclear expression of PG-21, SRC-1, and pCREB in regions of the lumbosacral spinal cord involved in pelvic innervation in young adult and aged rats [PDF]

, 2012
In rats, ageing results in dysfunctional patterns of micturition and diminished sexual reflexes that may reflect degenerative changes within spinal circuitry.
Amandusson, Anderson, Balazs, Berkley, Blanchet, Blanco, Blok, Breedlove, Breedlove, Burke, Chambers, Chambers, Collins, Dail, Davidson, De Cesare, Dering, Dering, Eika, Ernfors, Fargo, Ferrini, Finkbeiner, Frankel, Fraser, Ghanadian, Giuliano, Goldstein, Goldstein, Gonzalez, Gray, Gréco, Hancock, Hodges, Holmes, Hsu, Johnson, Jordan, Jordan, Jordan, Kepper, Kurz, Labombarda, Leo, Leslie, Lubischer, Marson, Marson, Marson, Marson, Marson, Matsumoto, Matsumoto, Matsumoto, Matsumoto, Matsumoto, Matsumoto, Mattson, Mayr, McKenna, McKenna, McManus, Meisel, Monks, Monks, Montminy, Nadelhaft, Nadelhaft, Nadelhaft, Nicolopoulos-Stournaras, Nordeen, O'Bryant, Osborne, Papka, Papka, Papka, Papka, Papka, Purinton, Ranson, Ranson, Ranson, Ranson, Ranson, Ranson, Reichardt, Santer, Schrøder, Sengelaub, Shibata, Smith, Smith, Tan, Tang, Tobin, Ulfhake, VanderHorst, Vera, Watkins, Watson, Williams, Wu, Wu, Yaici, Yamamoto, Yan, Yang, Yang, Yaïci   +108 more
core   +1 more source

Pathophysiology of Spinal Cord Injury (SCI) [PDF]

, 2023
Spinal cord injury (SCI) leads to paralysis, sensory, and autonomic nervous system dysfunctions. However, the pathophysiology of SCI is complex, and not limited to the nervous system.

core   +1 more source

A Rare Case of X-Linked Bulbo-Spinal Muscular Atrophy with Sensory Neuropathy and Tremors [PDF]

, 2021
Kennedy disease (KD) is also known as spino bulbar muscular atrophy caused by a tandem C-A-G tri-nucleotide repeat. It is an adult-onset X-linked recessive inherited neurodegenerative disease involving lower motor neuron damage with predominance of ...
Badshah, Mazhar, Hassan, Muhammad, Inayat, Tehmina, Iqbal, Mansoor, Irshad, Muhammad, Jan, Zakir, Shahzad, Waleed   +6 more
core   +1 more source

Differentially disrupted spinal cord and muscle energy metabolism in spinal and bulbar muscular atrophy. [PDF]

JCI Insight
Prior studies showed that polyglutamine-expanded androgen receptor (AR) is aberrantly acetylated and that deacetylation of the mutant AR by overexpression of nicotinamide adenine dinucleotide-dependent (NAD+-dependent) sirtuin 1 is protective in cell ...
DeBartolo D, Arnold FJ, Liu Y, Molotsky E, Tang HY, Merry DE.   +5 more
europepmc   +3 more sources

Myoclonus and other jerky movement disorders [PDF]

, 2022
Myoclonus and other jerky movements form a large heterogeneous group of disorders. Clinical neurophysiology studies can have an important contribution to support diagnosis but also to gain insight in the pathophysiology of different kind of jerks.
Caviness, John N., Dreissen, Yasmine E.M., Ganos, Christos, Ibrahim, Abubaker, Koelman, Johannes H.T.M., Stefani, Ambra, Tijssen, Marina A.J., van der Veen, Sterre   +7 more
core   +1 more source