Results 101 to 110 of about 193,176 (271)

Clinical Efficacy and Safety of Topical Roflumilast in Psoriasis: An Updated Systematic Review and Meta‐Analysis of Randomized Controlled Trials

open access: yesJEADV Clinical Practice, EarlyView.
ABSTRACT Background Traditional first‐line topical treatments for plaque psoriasis, particularly corticosteroids and vitamin D analogs, frequently have only limited efficacy for long‐term use, and present difficulties with safety and adherence. Objectives In this systematic review and meta‐analysis of randomized controlled trials (RCTs), we assessed ...
Aimal A. Khattak   +11 more
wiley   +1 more source

Enrichment of Hyaluronic Acid Binding Tumor Cells by Modulation of Selective Adhesion on Microgel Surfaces

open access: yesMacromolecular Rapid Communications, EarlyView.
We have developed a thermoresponsive microgel system for the selective enrichment of hyaluronic acid‐binding tumor cells. By modulating the adhesion on the microgel surface via temperature changes from 37°C to 30°C, we demonstrate a novel proof‐of‐principle for separating these tumor cell from white blood cells, which has potential applications in ...
Melanie Schmidt   +8 more
wiley   +1 more source

Loss‐of‐Function Variants in CPT1C: No Support for a Causal Role in Hereditary Spastic Paraplegia

open access: yesMovement Disorders, EarlyView.
Abstract Background Hereditary spastic paraplegias (HSPs) are neurodegenerative disorders characterized by lower‐limb spasticity. Pathogenic variants in CPT1C have been implicated in HSP. Objective The objective of this study was to assess whether CPT1C loss‐of‐function (LOF) variants are causally associated with HSP.
Rui Zhu   +17 more
wiley   +1 more source

Fostering Women's Political Leadership Through Government Accountability: Evidence From OECD Countries

open access: yesPublic Administration and Development, EarlyView.
ABSTRACT Women remain significantly underrepresented in political leadership worldwide. This study examines how different combinations of government accountability mechanisms enhance women's political representation (WPR) as a pathway to leadership in 30 OECD countries.
Samira Nazar, Seyed Ashkan Zarghami
wiley   +1 more source

Who is local and what do they know? Braiding knowledges within carnivore management in Europe

open access: yesPeople and Nature, EarlyView.
Abstract Growing recognition of Indigenous Peoples and traditional local communities as stewards of biodiversity has brought to the fore the issues of knowledge and value pluralism in conservation policy and practice. Given their basis in practical and multi‐generational experience, Indigenous and local knowledges are highly relevant to managing human ...
Hanna Pettersson   +6 more
wiley   +1 more source

The role of trust in wildlife damage response systems: One step towards coexistence between livestock farming and large carnivores?

open access: yesPeople and Nature, EarlyView.
Abstract Wildlife damage to livestock and crops is the primary cause of conflict and a major barrier to human–wildlife coexistence across Europe and beyond. Data on such damages play a key role in understanding and shaping these conflicts. Policy responses have emphasised prevention and compensation to support extensive husbandry practices; however ...
Katrina Marsden   +9 more
wiley   +1 more source

Engaging the public in plant science: Communication facilitators and barriers of scaling up a citizen science campaign

open access: yesPeople and Nature, EarlyView.
Abstract Volunteers have been involved in nature observations for decades through citizen science initiatives, providing large data sets as well as problem identification that allow a more complete understanding of many natural phenomena. Although communication is a core component in citizen science, the key factors that determine its effectiveness in ...
Kristiina Gibson   +18 more
wiley   +1 more source

Digitizing collections to unlock the full potential of palynology: A case study with the Smithsonian palynology collection

open access: yesPLANTS, PEOPLE, PLANET, EarlyView.
Large palynological collections have been built over decades and contain vital information. However, they are often difficult to access and use effectively. What is the point of having such collections if they are not fully utilizable? To solve this problem, we digitized the Smithsonian palynological collection using both light and confocal microscopy.
Carlos Jaramillo   +37 more
wiley   +1 more source

Ethnobotanical insights into the medicinal and food uses of Lamiaceae in the Mediterranean region: A systematic review and meta‐analysis

open access: yesPLANTS, PEOPLE, PLANET, EarlyView.
For generations, Mediterranean communities have used Lamiaceae or Labiatae plants like rosemary, thyme or mint to care for their health and to enrich their food. By bringing together dispersed knowledge from across the Mediterranean region, our review revealed the continuing relevance of Lamiaceae while also compiling past uses that may hold future ...
Fuencisla Cáceres   +3 more
wiley   +1 more source

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